Publications by authors named "Frederik O Bagger"

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Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome.
Hugues-Étienne Châtel-Soulet, Sabine Juge, Ana Luisa Pereira, Jonathan Seguin, Athimed El Taher, Frederik Otzen Bagger

Nat Commun· December 2025

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Recommendations for bioinformatics in clinical practice.
Ksenia Lavrichenko, Emilie Sofie Engdal, Rasmus L Marvig, Anders Jemt, Jone Marius Vignes, Frederik Otzen Bagger

Genome Med· October 2025

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Fever in Children with Cancer: Pathophysiological Insights Using Blood Transcriptomics.
Lotte Møller Smedegaard, Kia Hee Schultz Dungu, Yuliu Guo, Lisa Lyngsie Hjalgrim, Victoria Probst, Frederik Otzen Bagger

Int J Mol Sci· July 2025

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Glioblastoma cells increase expression of notch signaling and synaptic genes within infiltrated brain tissue.
Dylan Scott Lykke Harwood, Vilde Pedersen, Nicolai Schou Bager, Ane Yde Schmidt, Tobias Overlund Stannius, Frederik Otzen Bagger

Nat Commun· September 2024

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Similar genetic profile in early and late stage urothelial tract cancer.
Dag Rune Stormoen, Kristoffer Staal Rohrberg, Kent William Mouw, Katrine Ørum, Zoltan Szallasi, Frederik Otzen Bagger

J Cancer Res Clin Oncol· July 2024

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IMPROVE: a feature model to predict neoepitope immunogenicity through broad-scale validation of T-cell recognition.
Annie Borch, Ibel Carri, Birkir Reynisson, Heli M Garcia Alvarez, Kamilla K Munk, Frederik Otzen Bagger

Front Immunol· April 2024

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Host RNA Expression Signatures in Young Infants with Urinary Tract Infection: A Prospective Study.
Kia Hee Schultz Dungu, Emma Louise Malchau Carlsen, Jonathan Peter Glenthøj, Lisbeth Samsø Schmidt, Inger Merete Jørgensen, Frederik Otzen Bagger

Int J Mol Sci· April 2024

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Building flexible and robust analysis frameworks for molecular subtyping of cancers.
Christina Bligaard Pedersen, Benito Campos, Lasse Rene, Helene Scheel Wegener, Neeraja M Krishnan, Frederik Otzen Bagger

Mol Oncol· March 2024

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uPAR (PLAUR) Marks Two Intra-Tumoral Subtypes of Glioblastoma: Insights from Single-Cell RNA Sequencing.
Yue He, Kristina B V Døssing, Maria Rossing, Frederik Otzen Bagger, Andreas Kjaer

Int J Mol Sci· February 2024

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Combining Homologous Recombination-Deficient Testing and Functional RAD51 Analysis Enhances the Prediction of Poly(ADP-Ribose) Polymerase Inhibitor Sensitivity.
Lea M Korsholm, Maj Kjeldsen, Lorenzo Perino, Luca Mariani, Gitte-Bettina Nyvang, Frederik O Bagger

JCO Precis Oncol· February 2024

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BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis.
Magnús H Gíslason, Gül Sude Demircan, Marek Prachar, Benjamin Furtwängler, Juerg Schwaller, Frederik Otzen Bagger

Nucleic Acids Res· January 2024

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Whole genome sequencing in clinical practice.
Frederik Otzen Bagger, Line Borgwardt, Andreas Sand Jespersen, Anna Reimer Hansen, Birgitte Bertelsen

BMC Med Genomics· January 2024

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Clinical implication of genetic intratumor heterogeneity for targeted therapy in head and neck cancer.
Signe Buhl Gram, Daniela Alosi, Frederik Otzen Bagger, Olga Østrup, Christian von Buchwald

Acta Oncol· December 2023

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A Protocol for Low-Input RNA-Sequencing of Patients with Febrile Neutropenia Captures Relevant Immunological Information.
Victoria Probst, Lotte Møller Smedegaard, Arman Simonyan, Yuliu Guo, Olga Østrup, Frederik Otzen Bagger

Int J Mol Sci· June 2023

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The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53.
Maria-Riera Piqué-Borràs, Zivojin Jevtic, Frederik Otzen Bagger, Jonathan Seguin, Rathick Sivalingam

Blood· May 2023

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The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes.
Mette Louise Trempenau, Mikkel Bruhn Schuster, Sachin Pundhir, Mafalda Araujo Pereira, Adrija Kalvisa, Frederik Otzen Bagger

Leukemia· March 2023

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Benchmarking full-length transcript single cell mRNA sequencing protocols.
Victoria Probst, Arman Simonyan, Felix Pacheco, Yuliu Guo, Finn Cilius Nielsen, Frederik Otzen Bagger

BMC Genomics· December 2022

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H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway.
Anne Meldgaard Hansen, Ying Ge, Mikkel Bruhn Schuster, Sachin Pundhir, Janus Schou Jakobsen, Frederik Otzen Bagger

Sci Adv· March 2022

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A Comparison of Tools for Copy-Number Variation Detection in Germline Whole Exome and Whole Genome Sequencing Data.
Migle Gabrielaite, Mathias Husted Torp, Malthe Sebro Rasmussen, Sergio Andreu-Sánchez, Filipe Garrett Vieira, Frederik Otzen Bagger

Cancers (Basel)· December 2021

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Interpretable Autoencoders Trained on Single Cell Sequencing Data Can Transfer Directly to Data from Unseen Tissues.
Julie Sparholt Walbech, Savvas Kinalis, Ole Winther, Finn Cilius Nielsen, Frederik Otzen Bagger

Cells· December 2021

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Unveiling mRNP composition by fluorescence correlation and cross-correlation spectroscopy using cell lysates.
Àngels Mateu-Regué, Jan Christiansen, Frederik Otzen Bagger, Christian Hellriegel, Finn Cilius Nielsen

Nucleic Acids Res· November 2021

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Transcriptional characterization of human megakaryocyte polyploidization and lineage commitment.
Fizzah A Choudry, Frederik O Bagger, Iain C Macaulay, Samantha Farrow, Frances Burden

J Thromb Haemost· May 2021

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Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools.
Marek Prachar, Sune Justesen, Daniel Bisgaard Steen-Jensen, Stephan Thorgrimsen, Erik Jurgons, Frederik Otzen Bagger

Sci Rep· November 2020

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Single Cell Sequencing in Cancer Diagnostics.
Frederik Otzen Bagger, Victoria Probst

Adv Exp Med Biol· September 2020

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Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia.
Katharina Leonards, Marwa Almosailleakh, Samantha Tauchmann, Frederik Otzen Bagger, Cécile Thirant

Nat Commun· June 2020

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