Publications by authors named "Fredrik Wermeling"

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Autoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility.
Tilen Tršelič, Nathalie Pelo, Gregoire Martin de Fremont, Vaishnavi S Iyer, Elina Richardsdotter Andersson, Fredrik Wermeling

Proc Natl Acad Sci U S A· October 2025

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Green Listed v2.0: A Web Application for Streamlined Design of Custom CRISPR Screens.
Esbjörn Henkel, Zhaojun Li, Daniel Uvehag, Bernhard Schmierer, Martin Henkel, Fredrik Wermeling

CRISPR J· June 2025

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CRISPR/Cas9-mediated gene disruption determines the roles of MITF and CITED2 in human mast cell differentiation.
Jiezhen Mo, Fredrik Wermeling, Gunnar Nilsson, Joakim S Dahlin

Blood Adv· August 2024

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A genetic-epigenetic interplay at 1q21.1 locus underlies CHD1L-mediated vulnerability to primary progressive multiple sclerosis.
Majid Pahlevan Kakhki, Antonino Giordano, Chiara Starvaggi Cucuzza, Tejaswi Venkata S Badam, Samudyata Samudyata, Fredrik Wermeling

Nat Commun· July 2024

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MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors.
Katrine Ingelshed, Marit M Melssen, Pavitra Kannan, Arun Chandramohan, Anthony W Partridge, Fredrik Wermeling

iScience· June 2024

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High-content screening of drug combinations of an mPGES-1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance.
Ahlem Zaghmi, Erdem Aybay, Long Jiang, Mingmei Shang, Julia Steinmetz-Späh, Fredrik Wermeling

Mol Oncol· February 2024

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Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis.
Emmi Puuvuori, Yunbing Shen, Gry Hulsart-Billström, Bogdan Mitran, Bo Zhang, Fredrik Wermeling

J Nucl Med· February 2024

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Divergent and dominant anti-inflammatory effects of patient-derived anticitrullinated protein antibodies (ACPA) in arthritis development.
Bruno Raposo, Marcelo Afonso, Lena Israelsson, Heidi Wähämaa, Ragnhild Stålesen, Fredrik Wermeling

Ann Rheum Dis· May 2023

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MDM2 inhibitors, nutlin-3a and navtemadelin, retain efficacy in human and mouse cancer cells cultured in hypoxia.
Ada Lerma Clavero, Paula Lafqvist Boqvist, Katrine Ingelshed, Cecilia Bosdotter, Saikiran Sedimbi, Fredrik Wermeling

Sci Rep· March 2023

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Autoantibodies targeting malondialdehyde-modifications in rheumatoid arthritis regulate osteoclasts via inducing glycolysis and lipid biosynthesis.
Koji Sakuraba, Akilan Krishnamurthy, Jitong Sun, Xiaowei Zheng, Cheng Xu, Fredrik Wermeling

J Autoimmun· December 2022

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Biosynthesis of prostaglandin 15dPGJ -glutathione and 15dPGJ-cysteine conjugates in macrophages and mast cells via MGST3.
Julia Steinmetz-Späh, Jianyang Liu, Rajkumar Singh, Maria Ekoff, Sanjaykumar Boddul, Fredrik Wermeling

J Lipid Res· December 2022

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The MDM2 Inhibitor Navtemadlin Arrests Mouse Melanoma Growth and Potentiates Radiotherapy.
Katrine Ingelshed, Diana Spiegelberg, Pavitra Kannan, Linnéa Påvénius, Jessica Hacheney, Fredrik Wermeling

Cancer Res Commun· September 2022

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Modulating T-cell activation with antisense oligonucleotides targeting lymphocyte cytosolic protein 2.
Vaishnavi Srinivasan Iyer, Sanjaykumar V Boddul, Anna-Karin Johnsson, Bruno Raposo, Ravi K Sharma, Fredrik Wermeling

J Autoimmun· July 2022

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A CRISPR-p53 interactome with potential implications for clinical CRISPR/Cas9 use.
Long Jiang, Fredrik Wermeling

Oncoscience· May 2022

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CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based Therapies.
Long Jiang, Katrine Ingelshed, Yunbing Shen, Sanjaykumar V Boddul, Vaishnavi Srinivasan Iyer, Fredrik Wermeling

Cancer Res· January 2022

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Biased TCR gene usage in citrullinated Tenascin C specific T-cells in rheumatoid arthritis.
Ravi K Sharma, Sanjay V Boddul, Niyaz Yoosuf, Sara Turcinov, Anatoly Dubnovitsky, Fredrik Wermeling

Sci Rep· December 2021

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A rapid CRISPR competitive assay for and discovery of potential drug targets affecting the hematopoietic system.
Yunbing Shen, Long Jiang, Vaishnavi Srinivasan Iyer, Bruno Raposo, Anatoly Dubnovitsky, Fredrik Wermeling

Comput Struct Biotechnol J· September 2021

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In Vivo Lentiviral Gene Delivery of HLA-DR and Vaccination of Humanized Mice for Improving the Human T and B Cell Immune Reconstitution.
Suresh Kumar, Johannes Koenig, Andreas Schneider, Fredrik Wermeling, Sanjaykumar Boddul

Biomedicines· August 2021

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Identifying novel B-cell targets for chronic inflammatory autoimmune disease by screening of chemical probes in a patient-derived cell assay.
Yvonne Sundström, Ming-Mei Shang, Sudeepta Kumar Panda, Caroline Grönwall, Fredrik Wermeling

Transl Res· March 2021

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and functional characterization of human HLA-DRB1∗04 restricted T cell receptors.
Sanjaykumar V Boddul, Ravi Kumar Sharma, Anatoly Dubnovitsky, Bruno Raposo, Christina Gerstner, Fredrik Wermeling

J Transl Autoimmun· March 2021

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Designing custom CRISPR libraries for hypothesis-driven drug target discovery.
Vaishnavi Srinivasan Iyer, Long Jiang, Yunbing Shen, Sanjaykumar V Boddul, Sudeepta Kumar Panda, Fredrik Wermeling

Comput Struct Biotechnol J· August 2020

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An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma.
Julien Record, Anton Sendel, Joanna S Kritikou, Nikolai V Kuznetsov, Hanna Brauner, Fredrik Wermeling

Haematologica· May 2020

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IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints.
Sudeepta Kumar Panda, Gustaf Wigerblad, Long Jiang, Yanek Jiménez-Andrade, Vaishnavi Srinivasan Iyer, Fredrik Wermeling

Proc Natl Acad Sci U S A· February 2020

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Estimating Detection Limits of Potentiometric DNA Sensors Using Surface Plasmon Resonance Analyses.
Xingxing Xu, Asta Makaraviciute, Eldar Abdurakhmanov, Fredrik Wermeling, Shiyu Li

ACS Sens· January 2020

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Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization.
Anette Schulz, Long Jiang, Lisanne de Vor, Marcus Ehrström, Fredrik Wermeling

Cell Rep· October 2019

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