Publications by authors named "Frida Holm"

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Widespread remodeling of the RNA editome underlies transcriptional and clinical heterogeneity in pediatric acute lymphoblastic leukemia.
Sara Brin Rosenthal, Thomas Whisenant, Roman Sasik, Maria Rivera, Geena Il Defonso, Frida Holm

bioRxiv· December 2025

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Uncovering a role for METTL13 in malignant transformation of human hematopoietic stem cells and in the progression of pediatric leukemia.
Sabina Enlund, Chae-Eun Lim, Isabella Hoang, Sonali Joshi, Amanda Ramilo Amor, Frida Holm

Res Sq· October 2025

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METTL13 Promotes Pre-Leukemic Transformation and the Development of Pediatric Leukemia.
Sabina Enlund, Chae-Eun Lim, Isabella Hoang, Sonali Joshi, Amanda Ramilo Amor, Frida Holm

bioRxiv· August 2025

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A distinct alternative mRNA splicing profile identifies the oncogenic CD44 transcript variant 3 in KMT2A-rearranged pediatric T-cell acute lymphoblastic leukemia cells.
Amanda Ramilo Amor, Sabina Enlund, Indranil Sinha, Qingfei Jiang, Ola Hermanson, Frida Holm

Exp Hematol· May 2025

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The CNS microenvironment promotes leukemia cell survival by disrupting tumor suppression and cell cycle regulation in pediatric T-cell acute lymphoblastic leukemia.
Sabina Enlund, Indranil Sinha, Christina Neofytou, Amanda Ramilo Amor, Konstantinos Papadakis, Frida Holm

Exp Cell Res· April 2024

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Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing.
Maria Rivera, Haoran Zhang, Jessica Pham, Jane Isquith, Qingchen Jenny Zhou, Frida Holm

Cell Rep· February 2024

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Malignant A-to-I RNA editing by ADAR1 drives T-cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing.
Maria Rivera, Haoran Zhang, Jessica Pham, Jane Isquith, Qingchen Jenny Zhou, Frida Holm

Res Sq· June 2023

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Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T-cell acute lymphoblastic leukemia.
Sabina Enlund, Indranil Sinha, Amanda Ramilo Amor, Shahrzad Shirazi Fard, Ekaterina Pokrovskaja Tamm, Frida Holm

EJHaem· February 2023

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Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution.
Qingfei Jiang, Jane Isquith, Luisa Ladel, Adam Mark, Frida Holm

Cell Rep· January 2021

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Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation.
Qingfei Jiang, Jane Isquith, Maria Anna Zipeto, Raymond H Diep, Jessica Pham, Frida Holm

Cancer Cell· January 2019

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RNA editing-dependent epitranscriptome diversity in cancer stem cells.
Qingfei Jiang, Leslie A Crews, Frida Holm, Catriona H M Jamieson

Nat Rev Cancer· June 2017

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Selective microRNA-Offset RNA expression in human embryonic stem cells.
Suvi Asikainen, Liisa Heikkinen, Juuso Juhila, Frida Holm, Jere Weltner

PLoS One· February 2016

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Reversion to an embryonic alternative splicing program enhances leukemia stem cell self-renewal.
Frida Holm, Eva Hellqvist, Cayla N Mason, Shawn A Ali, Nathaniel Delos-Santos

Proc Natl Acad Sci U S A· December 2015

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Passaging techniques and ROCK inhibitor exert reversible effects on morphology and pluripotency marker gene expression of human embryonic stem cell lines.
Frida Holm, Hero Nikdin, Kristín Rós Kjartansdóttir, Giulia Gaudenzi, Kaj Fried

Stem Cells Dev· July 2013

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In vivo differentiated human embryonic stem cells can acquire chromosomal aberrations more frequently than in vitro during the same period.
Marco Zucchelli, Susanne Ström, Frida Holm, Helena Malmgren, Sigrid Sahlén

Stem Cells Dev· December 2012

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Improved cryopreservation of human hepatocytes using a new xeno free cryoprotectant solution.
Mohammed Saliem, Frida Holm, Rosita Bergström Tengzelius, Carl Jorns, Lisa-Mari Nilsson

World J Hepatol· May 2012

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Xeno-free culture of human pluripotent stem cells.
Rosita Bergström, Susanne Ström, Frida Holm, Anis Feki, Outi Hovatta

Methods Mol Biol· November 2011

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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.

Nat Biotechnol· November 2011

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No relationship between embryo morphology and successful derivation of human embryonic stem cell lines.
Susanne Ström, Kenny Rodriguez-Wallberg, Frida Holm, Rosita Bergström, Linda Eklund

PLoS One· December 2010

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An effective serum- and xeno-free chemically defined freezing procedure for human embryonic and induced pluripotent stem cells.
Frida Holm, Susanne Ström, José Inzunza, Duncan Baker, Anne-Marie Strömberg

Hum Reprod· May 2010

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Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells.

In Vitro Cell Dev Biol Anim· April 2010

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Derivation of 30 human embryonic stem cell lines--improving the quality.
Susanne Ström, Frida Holm, Rosita Bergström, Anne-Marie Strömberg, Outi Hovatta

In Vitro Cell Dev Biol Anim· April 2010

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A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes.
Outi Hovatta, Marisa Jaconi, Virpi Töhönen, Frédérique Béna, Stefania Gimelli, Frida Holm

PLoS One· April 2010

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Immortalized human skin fibroblast feeder cells support growth and maintenance of both human embryonic and induced pluripotent stem cells.
Christian Unger, Shuping Gao, Marie Cohen, Marisa Jaconi, Rosita Bergstrom, Frida Holm

Hum Reprod· October 2009

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