Publications by authors named "Funian Lu"

Claim this Profile
T
The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy.
Yu Fu, Xiaoyan Kang, Wenting Li, Zanhong Wang, Wanwan Luo, Funian Lu

Cell Rep· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Heterogeneous cellular responses to hyperthermia support combined intraperitoneal hyperthermic immunotherapy for ovarian cancer mouse models.
Xingyuan Hu, Xiaoyan Kang, Faming Zhao, Yaoyuan Cui, Yu Fu, Funian Lu

Sci Transl Med· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genomic profiling of a multi-lineage and multi-passage patient-derived xenograft biobank reflects heterogeneity of ovarian cancer.
Tianyu Qin, Zhe Hu, Li Zhang, Funian Lu, Rourou Xiao

Cell Rep Med· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Proteogenomic insights into early-onset endometrioid endometrial carcinoma: predictors for fertility-sparing therapy response.
Zhe Hu, Zimeng Wu, Wei Liu, Yan Ning, Jingbo Liu, Funian Lu

Nat Genet· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comprehensive multi-omics analysis reveals WEE1 as a synergistic lethal target with hyperthermia through CDK1 super-activation.
Xiaohang Yang, Xingyuan Hu, Jingjing Yin, Wenting Li, Yu Fu, Funian Lu

Nat Commun· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multiomic analysis of cervical squamous cell carcinoma identifies cellular ecosystems with biological and clinical relevance.
Junpeng Fan, Funian Lu, Tianyu Qin, Wenju Peng, Xucui Zhuang

Nat Genet· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MRE11:p.K464R mutation mediates olaparib resistance by enhancing DNA damage repair in HGSOC.
Xucui Zhuang, Rourou Xiao, Yu Fu, Bin Yang, Junpeng Fan, Funian Lu

Cell Biosci· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
,
, a potential predictor of prognosis, promotes CD8 T‑cell infiltration in ovarian serous carcinoma by inducing CCL5 secretion.
Wei Wang, Si Liu, Funian Lu, Bin Yang, Xucui Zhuang

Oncol Rep· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.
Yu Fu, Bin Yang, Yaoyuan Cui, Xingyuan Hu, Xi Li, Funian Lu

J Immunother Cancer· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Codelivery of adavosertib and olaparib by tumor-targeting nanoparticles for augmented efficacy and reduced toxicity.
Wei Wang, Yuxuan Xiong, Xingyuan Hu, Funian Lu, Tianyu Qin

Acta Biomater· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multi-omics characterization of silent and productive HPV integration in cervical cancer.
Junpeng Fan, Yu Fu, Wenju Peng, Xiong Li, Yuanming Shen, Funian Lu

Cell Genom· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Spatial heterogeneity of infiltrating T cells in high-grade serous ovarian cancer revealed by multi-omics analysis.
Bin Yang, Xiong Li, Wei Zhang, Junpeng Fan, Yong Zhou, Funian Lu

Cell Rep Med· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Harnessing preclinical models for the interrogation of ovarian cancer.
Tianyu Qin, Junpeng Fan, Funian Lu, Li Zhang, Chen Liu

J Exp Clin Cancer Res· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutation profiles in circulating cell-free DNA predict acquired resistance to olaparib in high-grade serous ovarian carcinoma.
Dianxing Hu, Ensong Guo, Bin Yang, Xu Qin, Yu Fu, Funian Lu

Cancer Sci· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Diversity of Vaginal Microbiota Predicts Neoadjuvant Chemotherapy Responsiveness in Locally Advanced Cervical Cancer.
Zizhuo Wang, Rourou Xiao, Jia Huang, Xu Qin, Dianxing Hu, Funian Lu

Microb Ecol· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibiting the IRE1α Axis of the Unfolded Protein Response Enhances the Antitumor Effect of AZD1775 in TP53 Mutant Ovarian Cancer.
Rourou Xiao, Lixin You, Li Zhang, Xichen Guo, Ensong Guo, Funian Lu

Adv Sci (Weinh)· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AZD5153 reverses palbociclib resistance in ovarian cancer by inhibiting cell cycle-related proteins and the MAPK/PI3K-AKT pathway.
Chen Liu, Yuhan Huang, Tianyu Qin, Lixin You, Funian Lu

Cancer Lett· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Immunological Role of CDK4/6 and Potential Mechanism Exploration in Ovarian Cancer.
Chen Liu, Yuhan Huang, Yaoyuan Cui, Jun Zhou, Xu Qin, Funian Lu

Front Immunol· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
WEE1 inhibition induces anti-tumor immunity by activating ERV and the dsRNA pathway.
Ensong Guo, Rourou Xiao, Yifan Wu, Funian Lu, Chen Liu, Yiling Lu

J Exp Med· January 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Impact of chemotherapy and immunotherapy on the composition and function of immune cells in COVID-19 convalescent with gynecological tumors.
Tianyu Qin, Ensong Guo, Funian Lu, Yu Fu, Si Liu

Aging (Albany NY)· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Trends and age-period-cohort effects on mortality of the three major gynecologic cancers in China from 1990 to 2019: Cervical, ovarian and uterine cancer.
Zhenkun Wang, Ensong Guo, Bin Yang, Rourou Xiao, Funian Lu

Gynecol Oncol· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Clinical and molecular characteristics of COVID-19 patients with persistent SARS-CoV-2 infection.
Bin Yang, Junpeng Fan, Jia Huang, Ensong Guo, Yu Fu, Funian Lu

Nat Commun· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MEK Inhibition Remodels the Immune Landscape of Mutant Tumors to Overcome Resistance to PARP and Immune Checkpoint Inhibitors.
Bin Yang, Xi Li, Yu Fu, Ensong Guo, Youqiong Ye, Funian Lu

Cancer Res· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dynamics and Correlation Among Viral Positivity, Seroconversion, and Disease Severity in COVID-19 : A Retrospective Study.
Yu Fu, Yongsheng Li, Ensong Guo, Liang He, Jia Liu, Funian Lu

Ann Intern Med· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fecal microbiota transplantation mitigates vaginal atrophy in ovariectomized mice.
Jia Huang, Wanying Shan, Fuxia Li, Zizhuo Wang, Jing Cheng, Funian Lu, Rajluxmee Beejadhursing

Aging (Albany NY)· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis