Publications by authors named "Futoshi Okada"

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AMIGO2 accelerates tumor progression by inducing a cancer stem cell-like phenotype.
Hee Kyung Seong, Mitsuhiko Osaki, Runa Izutsu, Jumond P Jehung, Reo Sato, Futoshi Okada

Sci Rep· September 2025

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AMIGO2 expression at the invasive front of bladder cancer predicts recurrence-free and overall survival after radical cystectomy.
Atsushi Yamamoto, Runa Izutsu, Heekyung Seong, Ryutaro Shimizu, Ryoma Nishikawa, Futoshi Okada

Oncol Lett· July 2025

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Hepatic Stellate Cells Activated by Cancer Cell-derived AMIGO2-containing Small Extracellular Vesicles Promote Cancer Cell Migration by Producing IL-8.
Runa Izutsu, Mitsuhiko Osaki, Heekyung Seong, Reo Sato, Futoshi Okada

Anticancer Res· April 2025

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Cancer prevention: past challenges and future directions.
HeeKyung Seong, Runa Izutsu, Mitsuhiko Osaki, Futoshi Okada

Genes Environ· February 2025

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AMIGO2 enhances the invasive potential of colorectal cancer by inducing EMT.
Runa Izutsu, Mitsuhiko Osaki, HeeKyung Seong, Sanami Ogata, Reo Sato, Futoshi Okada

Cancer Gene Ther· December 2024

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Prevention of liver metastasis via the pharmacological suppression of AMIGO2 expression in tumor cells.
HeeKyung Seong, Yusuke Kanda, Runa Izutsu, Jumond P Jehung, Junichi Hamada, Futoshi Okada

Sci Rep· November 2024

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AMIGO2 is involved in the spread of peritoneal metastasis in serous ovarian cancer via promoting adhesion to the peritoneal mesothelial cells.
Yuki Iida, Mitsuhiko Osaki, Shinya Sato, Runa Izutsu, HeeKyung Seong, Futoshi Okada

Int J Clin Oncol· September 2024

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Exosomal miR-493 suppresses MAD2L1 and induces chemoresistance to intraperitoneal paclitaxel therapy in gastric cancer patients with peritoneal metastasis.
Masahiro Makinoya, Kozo Miyatani, Yoshiaki Matsumi, Yu Sakano, Shota Shimizu, Futoshi Okada

Sci Rep· May 2024

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Corrigendum to "Increased chemokine ligand 26 expression and its involvement in epithelial-mesenchymal transition in the endometrium with adenomyosis" [Volume 52, Issue 9 (2023) 102645].
Ai Ikebuchi, Mitsuhiko Osaki, Ikumi Wada, Hiroki Nagata, Kei Nagira, Futoshi Okada

J Gynecol Obstet Hum Reprod· March 2024

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Increased chemokine ligand 26 expression and its involvement in epithelial-mesenchymal transition in the endometrium with adenomyosis.
Ai Ikebuchi, Mitsuhiko Osaki, Ikumi Wada, Hiroki Nagata, Kei Nagira, Futoshi Okada

J Gynecol Obstet Hum Reprod· November 2023

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AMIGO2 expression as a predictor of recurrence in cervical cancer with intermediate risk.
Yuki Iida, Mitsuhiko Osaki, Shinya Sato, Runa Izutsu, Heekyung Seong, Futoshi Okada

Mol Clin Oncol· July 2023

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A Standardized Extract of Cultured Up-regulates COX-2 in Inflammation-related Malignant Progressive Fibrosarcoma Cell Clone QRsP-11.
Takao Kitagawa, Shajedul Islam, Byron Baron, Kazuhiro Tokuda, Durga Paudel, Futoshi Okada

Anticancer Res· March 2023

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Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis.
Kosaku Okuda, Kengo Nakahara, Akihiro Ito, Yuta Iijima, Ryosuke Nomura, Futoshi Okada

Nat Commun· February 2023

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Kidney organoid derived from renal tissue stem cells is a useful tool for histopathological assessment of nephrotoxicity in a cisplatin-induced acute renal tubular injury model.
Shota Ueno, Kenji Kokura, Yasushi Kuromi, Mitsuhiko Osaki, Futoshi Okada

J Toxicol Pathol· October 2022

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Liver Metastasis Formation Is Defined by AMIGO2 Expression via Adhesion to Hepatic Endothelial Cells in Human Gastric and Colorectal Cancer Cells.
Runa Izutsu, Mitsuhiko Osaki, Jumond P Jehung, Hee Kyung Seong, Futoshi Okada

Pathol Res Pract· September 2022

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The impact of AMIGO2 on prognosis and hepatic metastasis in gastric cancer patients.
Keisuke Goto, Masaki Morimoto, Mitsuhiko Osaki, Akimitsu Tanio, Runa Izutsu, Futoshi Okada

BMC Cancer· March 2022

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MTA1, a metastasis‑associated protein, in endothelial cells is an essential molecule for angiogenesis.
Mizuho Ishikawa, Mitsuhiko Osaki, Narumi Uno, Takahito Ohira, Hiroyuki Kugoh, Futoshi Okada

Mol Med Rep· January 2022

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Newly Invented Micellized Vitamin K2 Recovered Prolonged Prothrombin Time under Obstructive Jaundice in Rats with Bile Duct Ligation.
Yoshiki Hoshino, Takaaki Sugihara, Suguru Ikeda, Ryohei Tarumoto, Yukako Matsuki, Futoshi Okada

J Nutr Sci Vitaminol (Tokyo)· January 2022

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AMIGO2 contained in cancer cell-derived extracellular vesicles enhances the adhesion of liver endothelial cells to cancer cells.
Runa Izutsu, Mitsuhiko Osaki, Hideyuki Nemoto, Maho Jingu, Ryo Sasaki, Futoshi Okada

Sci Rep· January 2022

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Establishment of an antibody specific for AMIGO2 improves immunohistochemical evaluation of liver metastases and clinical outcomes in patients with colorectal cancer.
Keisuke Goto, Mitsuhiko Osaki, Runa Izutsu, Hiroshi Tanaka, Ryo Sasaki, Futoshi Okada

Diagn Pathol· January 2022

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AMIGO2 as a novel indicator of liver metastasis in patients with colorectal cancer.
Akimitsu Tanio, Hiroaki Saito, Masataka Amisaki, Kazushi Hara, Ken Sugezawa, Futoshi Okada

Oncol Lett· April 2021

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Inflammation-Related Carcinogenesis: Lessons from Animal Models to Clinical Aspects.
Futoshi Okada, Runa Izutsu, Keisuke Goto, Mitsuhiko Osaki

Cancers (Basel)· February 2021

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Loss of the cystine/glutamate antiporter in melanoma abrogates tumor metastasis and markedly increases survival rates of mice.
Mami Sato, Kunishige Onuma, Mio Domon, Shun Hasegawa, Ami Suzuki, Futoshi Okada

Int J Cancer· December 2020

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Splice variants of lysosome‑associated membrane proteins 2A and 2B are involved in sunitinib resistance in human renal cell carcinoma cells.
Ryoma Nishikawa, Mitsuhiko Osaki, Ryo Sasaki, Mizuho Ishikawa, Tetsuya Yumioka, Futoshi Okada

Oncol Rep· November 2020

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Pretreatment with cilnidipine attenuates hypoxia/reoxygenation injury in HL-1 cardiomyocytes through enhanced NO production and action potential shortening.
Hiroyuki Minato, Ichiro Hisatome, Yasutaka Kurata, Tomomi Notsu, Naoe Nakasone, Futoshi Okada

Hypertens Res· May 2020

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