Publications by authors named "Fuyan Xu"

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Discovery of a Novel G9a-Selective Inhibitor for Hepatocellular Carcinoma Treatment.
Xiaoyu Mu, Jiao Li, Rong Wei, Jian-Kang Zhou, Yue Ming, Fuyan Xu, Xiaomin Xu

ACS Med Chem Lett· November 2025

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A Circular RNA Promotes Tumor Metastasis through Stabilizing MSI2 Protein in Pancreatic Ductal Adenocarcinoma.
Zhang Li, Lanyang Gao, Yang Yang, Yue Ming, Wenrong Liu, Fuyan Xu

Research (Wash D C)· October 2025

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Repurposing chlorpromazine for the treatment of triple-negative breast cancer growth and metastasis based on modulation of mitochondria-mediated apoptosis and autophagy/mitophagy.
Yamin Pu, Fuyan Xu, Anqi He, Ru Li, Xiangxiu Wang

Br J Cancer· June 2025

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Targeting oncogenic transcriptional factor c-myc by oligonucleotide PROTAC for the treatment of hepatocellular carcinoma.
Min Ai, Hulin Ma, Jianhua He, Fuyan Xu, Yue Ming

Eur J Med Chem· December 2024

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Penfluridol inhibits melanoma growth and metastasis through enhancing von Hippel‒Lindau tumor suppressor-mediated cancerous inhibitor of protein phosphatase 2A (CIP2A) degradation.
Fuyan Xu, Jiao Li, Min Ai, Tingting Zhang, Yue Ming, Xiaomin Xu

MedComm (2020)· October 2024

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circNEIL3 inhibits tumor metastasis through recruiting the E3 ubiquitin ligase Nedd4L to degrade YBX1.
Shuang Chen, Ke Li, Jiawei Guo, Hai-Ning Chen, Yue Ming, Fuyan Xu, Heng Xu

Proc Natl Acad Sci U S A· March 2023

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Targeting Ferroptosis Pathway to Combat Therapy Resistance and Metastasis of Cancer.
Xuan Liu, Yiqian Zhang, Xuyi Wu, Fuyan Xu, Hongbo Ma

Front Pharmacol· June 2022

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Repurposed antipsychotic chlorpromazine inhibits colorectal cancer and pulmonary metastasis by inducing G2/M cell cycle arrest, apoptosis, and autophagy.
Fuyan Xu, Huizhi Xi, Mengya Liao, Yiqian Zhang, Hongbo Ma, Qiang Xue

Cancer Chemother Pharmacol· March 2022

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Repurposing of antipsychotic trifluoperazine for treating brain metastasis, lung metastasis and bone metastasis of melanoma by disrupting autophagy flux.
Yong Xia, Fuyan Xu, Meiping Xiong, Hao Yang, Wentao Lin, Qiang Xue

Pharmacol Res· January 2021

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Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis.
Yong Xia, Chengsen Jia, Qiang Xue, Jinrui Jiang, Yao Xie, Fuyan Xu

Front Pharmacol· September 2019

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Structural basis for efonidipine block of a voltage-gated Ca channel.
Fuyan Xu, Weixi Xiong, Yiman Huang, Jianghua Shen, Dong Zhou

Biochem Biophys Res Commun· June 2019

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Repositioning antipsychotic fluphenazine hydrochloride for treating triple negative breast cancer with brain metastases and lung metastases.
Fuyan Xu, Yong Xia, Zhanzhan Feng, Wentao Lin, Qiang Xue

Am J Cancer Res· March 2019

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The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis.
Zhanzhan Feng, Yong Xia, Tiantao Gao, Fuyan Xu, Qian Lei, Qiang Xue

Cell Death Dis· September 2018

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