Publications by authors named "GJ Gerfen"

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Lactoperoxidase catalytically oxidize hydrogen sulfide via intermediate formation of sulfheme derivatives.
Bessie B Ríos-González, Andrea Domán, Tamás Ditrói, Dorottya Garai, Leishka D Crespo, Gary J Gerfen

Redox Biochem Chem· June 2024

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Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis.
Ayala G Carl, Lawrence D Harris, Mu Feng, Lars U Nordstrøm, Gary J Gerfen

Biochemistry· July 2020

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The active site of the branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.
Ghader Bashiri, Tyler L Grove, Subray S Hegde, Thomas Lagautriere, Gary J Gerfen

J Biol Chem· August 2019

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Oxidative decarboxylation of pyruvate by 1-deoxy-d-xyulose 5-phosphate synthase, a central metabolic enzyme in bacteria.
Alicia A DeColli, Natalia S Nemeria, Ananya Majumdar, Gary J Gerfen, Frank Jordan

J Biol Chem· July 2018

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L-tyrosine induces the production of a pyomelanin-like pigment by the parasitic yeast-form of Histoplasma capsulatum.
Rodrigo Almeida-Paes, Fernando Almeida-Silva, Gabriela Costa Maia Pinto, Marcos de Abreu Almeida, Mauro de Medeiros Muniz, Gary J Gerfen

Med Mycol· June 2018

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Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine.
Kimberly J Briggs, Peppi Koivunen, Shugeng Cao, Keriann M Backus, Benjamin A Olenchock, Gary J Gerfen

Cell· June 2016

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Distinct Interaction Modes of the Kinesin-13 Motor Domain with the Microtubule.
Chandrima Chatterjee, Matthieu P M H Benoit, Vania DePaoli, Juan D Diaz-Valencia, Ana B Asenjo, Gary J Gerfen

Biophys J· April 2016

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GLP-1 Cleavage Product Reverses Persistent ROS Generation After Transient Hyperglycemia by Disrupting an ROS-Generating Feedback Loop.
Ferdinando Giacco, Xueliang Du, Anna Carratú, Gary J Gerfen, Maria D'Apolito

Diabetes· September 2015

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Catalytic intermediates of inducible nitric-oxide synthase stabilized by the W188H mutation.
Joseph Sabat, Tsuyoshi Egawa, Changyuan Lu, Dennis J Stuehr, Gary J Gerfen

J Biol Chem· March 2013

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Biosynthesis and functions of a melanoid pigment produced by species of the sporothrix complex in the presence of L-tyrosine.
Rodrigo Almeida-Paes, Susana Frases, Glauber de Sousa Araújo, Manoel Marques Evangelista de Oliveira, Gary J Gerfen

Appl Environ Microbiol· December 2012

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Two tyrosyl radicals stabilize high oxidation states in cytochrome C oxidase for efficient energy conservation and proton translocation.
Michelle A Yu, Tsuyoshi Egawa, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, Victor Guallar, Gary J Gerfen

J Am Chem Soc· March 2012

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Investigating the intermediates in the reaction of ribonucleoside triphosphate reductase from Lactobacillus leichmannii: An application of HF EPR-RFQ technology.
Julia Manzerova, Vladimir Krymov, Gary J Gerfen

J Magn Reson· December 2011

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Radical formation in cytochrome c oxidase.
Michelle A Yu, Tsuyoshi Egawa, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, Syun-Ru Yeh, Gary J Gerfen

Biochim Biophys Acta· October 2011

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Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2.
Ah-lim Tsai, Gang Wu, Corina E Rogge, Jian-Ming Lü, Sheng Peng, Gary J Gerfen

J Inorg Biochem· March 2011

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EPR characterization of ascorbyl and sulfur dioxide anion radicals trapped during the reaction of bovine Cytochrome c Oxidase with molecular oxygen.
Michelle A Yu, Tsuyoshi Egawa, Syun-Ru Yeh, Denis L Rousseau, Gary J Gerfen

J Magn Reson· April 2010

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The structure of p85ni in class IA phosphoinositide 3-kinase exhibits interdomain disorder.
K Ilker Sen, Haiyan Wu, Jonathan M Backer, Gary J Gerfen

Biochemistry· March 2010

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Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical.
Gregory J S Lohman, Gary J Gerfen, Joanne Stubbe

Biochemistry· February 2010

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Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutants.
Haiyan Wu, S Chandra Shekar, Rory J Flinn, Mirvat El-Sibai, Bijay S Jaiswal, Gary J Gerfen

Proc Natl Acad Sci U S A· December 2009

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An oxyferrous heme/protein-based radical intermediate is catalytically competent in the catalase reaction of Mycobacterium tuberculosis catalase-peroxidase (KatG).
Javier Suarez, Kalina Ranguelova, Andrzej A Jarzecki, Julia Manzerova, Vladimir Krymov, Gary J Gerfen

J Biol Chem· March 2009

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Characterization of the peroxidase mechanism upon reaction of prostacyclin synthase with peracetic acid. Identification of a tyrosyl radical intermediate.
Hui-Chun Yeh, Gary J Gerfen, Jinn-Shyan Wang, Ah-Lim Tsai, Lee-Ho Wang

Biochemistry· February 2009

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High frequency EPR on dilute solutions of the single molecule magnet Ni(4).
G de Loubens, A D Kent, V Krymov, G J Gerfen, C C Beedle

J Appl Phys· April 2008

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Radical sites in Mycobacterium tuberculosis KatG identified using electron paramagnetic resonance spectroscopy, the three-dimensional crystal structure, and electron transfer couplings.
Kalina Ranguelova, Stefania Girotto, Gary J Gerfen, Shengwei Yu, Javier Suarez

J Biol Chem· March 2007

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EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase.
Steven O Mansoorabadi, Javier Seravalli, Cristina Furdui, Vladimir Krymov, Gary J Gerfen

Biochemistry· June 2006

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The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4.
Madhuri Chattopadhyay, Eric D Walter, Dustin J Newell, Pilgrim J Jackson, Eliah Aronoff-Spencer, Gary J Gerfen

J Am Chem Soc· September 2005

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Determination of the structural environment of the tyrosyl radical in prostaglandin H2 synthase-1: a high frequency ENDOR/EPR study.
John C Wilson, Gang Wu, Ah-lim Tsai, Gary J Gerfen

J Am Chem Soc· February 2005

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