Publications by authors named "GL Greene"

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Progesterone receptors drive advanced breast cancer phenotypes including circulating tumor- and stem-like cell expansion in the context of mutation.
Thu H Truong, Noelle E Gillis, Amy R Dwyer, Rosemary J Huggins, Kyla M Hagen, Geoffrey L Greene

bioRxiv· November 2025

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Ceramide-induced Endoplasmic Reticulum Stress as a Targetable Vulnerability in Endocrine Therapy-Resistant Breast Cancer.
Purab Pal, Shweta Chitkara, Godwin K Sarpey, Fatimah Alani, Huiping Zhao, Geoffrey L Greene

bioRxiv· August 2025

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PARP-1 as a novel target in endocrine-resistant breast cancer.
Azzurra Zicarelli, Marianna Talia, Muriel Lainé, Rosamaria Lappano, Marcello Maggiolini, Geoffrey L Greene

J Exp Clin Cancer Res· June 2025

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Lasofoxifene as a potential treatment for aromatase inhibitor-resistant ER-positive breast cancer.
Muriel Lainé, Marianne E Greene, Justyna D Kurleto, Grazyna Bozek, Tiffany Leng, Geoffrey L Greene

Breast Cancer Res· June 2024

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ERα/PR crosstalk is altered in the context of the ERα Y537S mutation and contributes to endocrine therapy-resistant tumor proliferation.
Rosemary J Huggins, Geoffrey L Greene

NPJ Breast Cancer· November 2023

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Reinvestigating the Synthesis and Characterization of Ethyl 3-[5-(2-Ethoxycarbonyl-1-methylvinyloxy)-1-methyl-1-indol-3-yl]-but-2-enoate.
Nan-Sheng Li, Joseph A Piccirilli, Geoffrey L Greene

ACS Omega· September 2023

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Glucocorticoid Receptor Activation in Lobular Breast Cancer Is Associated with Reduced Cell Proliferation and Promotion of Metastases.
Baylee A Porter, Candace Frerich, Muriel Lainé, Abigail B Clark, Ishrat Durdana, Geoffrey L Greene

Cancers (Basel)· September 2023

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Evaluating steroid hormone receptor interactions using the live-cell NanoBRET proximity assay.
Rosemary J Huggins, David Hosfield, Amira Ishag-Osman, Keemin Lee, Elia Ton-That, Geoffrey L Greene

bioRxiv· July 2023

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Demethylation of dimethyl phosphonate esters with sodium ethanethiolate: Improved synthesis of 5'-methylene substituted 2',5'-deoxyribonucleotides.
Nan-Sheng Li, Joseph A Piccirilli, Geoffrey L Greene

Nucleosides Nucleotides Nucleic Acids· May 2023

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Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains.
Thomas E Speltz, Zeyu Qiao, Colin S Swenson, Xianghang Shangguan, John S Coukos, Geoffrey L Greene

Nat Biotechnol· April 2023

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Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells.
G R Hancock, K S Young, D J Hosfield, C Joiner, E A Sullivan, G L Greene

NPJ Breast Cancer· December 2022

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Labeling of a mutant estrogen receptor with an Affimer in a breast cancer cell line.
Pin Ren, Christian Tiede, Sean W Fanning, Thomas Adams, Valerie Speirs, Geoffrey L Greene

Biophys J· October 2022

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Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in mutant breast cancer cells.
David J Hosfield, Sandra Weber, Nan-Sheng Li, Madline Sauvage, Carstyn F Joiner, Geoffrey L Greene

Elife· May 2022

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Endocrine Therapy-Resistant Breast Cancer Cells Are More Sensitive to Ceramide Kinase Inhibition and Elevated Ceramide Levels Than Therapy-Sensitive Breast Cancer Cells.
Purab Pal, Alec Millner, Svetlana E Semina, Rosemary J Huggins, Logan Running, Geoffrey L Greene

Cancers (Basel)· May 2022

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Selective pressure of endocrine therapy activates the integrated stress response through NFκB signaling in a subpopulation of ER positive breast cancer cells.
Svetlana E Semina, Purab Pal, Nidhi S Kansara, Rosemary J Huggins, Elaine T Alarid, Geoffrey L Greene

Breast Cancer Res· March 2022

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Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer.
Christopher G Mayne, Weiyi Toy, Kathryn E Carlson, Trusha Bhatt, Sean W Fanning, Geoffrey L Greene

Mol Cancer Res· September 2021

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A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice.
Matthew W Boudreau, Darjan Duraki, Lawrence Wang, Chengjian Mao, Ji Eun Kim, Geoffrey L Greene

Sci Transl Med· July 2021

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Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer.
Muriel Lainé, Sean W Fanning, Ya-Fang Chang, Bradley Green, Marianne E Greene, Geoffrey L Greene

Breast Cancer Res· May 2021

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Facilitating Drug Discovery in Breast Cancer by Virtually Screening Patients Using In Vitro Drug Response Modeling.
Robert F Gruener, Alexander Ling, Ya-Fang Chang, Gladys Morrison, Paul Geeleher, Geoffrey L Greene

Cancers (Basel)· February 2021

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Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer.
Balkees Abderrahman, Philipp Y Maximov, Ramona F Curpan, Sean W Fanning, Jay S Hanspal, Geoffrey L Greene

Mol Cancer Ther· January 2021

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First Precision Measurement of the Parity Violating Asymmetry in Cold Neutron Capture on ^{3}He.
M T Gericke, S Baeßler, L Barrón-Palos, N Birge, J D Bowman, G L Greene

Phys Rev Lett· September 2020

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The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast Cancers.
Irida Kastrati, Stacey E P Joosten, Svetlana E Semina, Luis H Alejo, Svitlana D Brovkovych, Geoffrey L Greene

Mol Cancer Res· July 2020

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The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells.
Philipp Y Maximov, Balkees Abderrahman, Yousef M Hawsawi, Yue Chen, Charles E Foulds, Geoffrey L Greene

Mol Pharmacol· July 2020

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Imaging Fluorescence of He_{2}^{*} Excimers Created by Neutron Capture in Liquid Helium II.
X Wen, S R Bao, L McDonald, J Pierce, G L Greene

Phys Rev Lett· April 2020

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The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer.
Kimberly J Cocce, Jeff S Jasper, Taylor K Desautels, Logan Everett, Suzanne Wardell, Geoffrey L Greene

Cell Rep· October 2019

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