Publications by authors named "GQ Gong"

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A KCNQ4 Gene Variant (c.701A > G; p.His234Arg) in a Chinese Family With Nonsyndromic Deafness 2A.
Guo-Qing Gong, Cheng-Cheng Huang, Hui-Yu Jin, Zhao Zhang, Chang-Liang Yang

Mol Genet Genomic Med· March 2025

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Making PI3K superfamily enzymes run faster.
Grace Q Gong, Madhangopal Anandapadamanaban, Md Saiful Islam, Iain M Hay, Maxime Bourguet

Adv Biol Regul· January 2025

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ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding.
Grace Q Gong, Glenn R Masson, Woo-Jeong Lee, James M J Dickson, Jackie D Kendall

Biochem J· December 2024

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Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function.
Manojit M Swamynathan, Shan Kuang, Kaitlin E Watrud, Mary R Doherty, Charlotte Gineste, Grace Q Gong

Science· October 2024

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Precision Targeting of Mutant PI3Kα.
Grace Q Gong, Bart Vanhaesebroeck

Cancer Discov· February 2024

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A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Grace Q Gong, Benoit Bilanges, Ben Allsop, Glenn R Masson, Victoria Roberton

Nature· June 2023

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Dropouts From Sublingual Immunotherapy and the Transition to Subcutaneous Immunotherapy in House Dust Mite-Sensitized Allergic Rhinitis Patients.
Huan Chen, Guo-Qing Gong, Mei Ding, Xiang Dong, Yuan-Li Sun

Front Allergy· January 2022

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Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists.
Lin Lin, Guangyao Lin, Qingtong Zhou, Ross A D Bathgate, Grace Qun Gong

Bioorg Chem· May 2021

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Characterization of coal-based fulvic acid and the construction of a fulvic acid molecular model.
Guan-Qun Gong, Xin Yuan, Ying-Jie Zhang, Ya-Jun Li, Wei-Xin Liu

RSC Adv· January 2020

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A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion.
Samantha D Heitz, David J Hamelin, Reece M Hoffmann, Nili Greenberg, Gilbert Salloum, Grace Q Gong

J Biol Chem· March 2019

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Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds.
Grace Qun Gong, Ke Wang, Xin-Chuan Dai, Yan Zhou, Rajesh Basnet

Acta Pharmacol Sin· December 2018

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High-throughput screening campaigns against a PI3Kα isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds.
Jia Wang, Grace Qun Gong, Yan Zhou, Woo-Jeong Lee, Christina Maree Buchanan

Acta Pharmacol Sin· November 2018

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Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention.
Rajesh Basnet, Grace Qun Gong, Chenyao Li, Ming-Wei Wang

Acta Pharm Sin B· September 2018

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Dual inhibition of HY023016 based on binding properties of platelet membrane receptor subunit glycoprotein Ibα and thrombin exosites.
Qiu-Fang Chen, Shuang Cui, Hui-Liang Shen, Xiang Chen, Yun-Zhan Li, Guo-Qing Gong

Eur J Pharmacol· March 2018

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Discovery of novel limonin derivatives as potent anti-inflammatory and analgesic agents.
Shao-Chi Wang, Yun Yang, Jing Liu, Ai-Dou Jiang, Zhao-Xing Chu, Guo-Qing Gong

Chin J Nat Med· March 2018

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Combining properties of different classes of PI3Kα inhibitors to understand the molecular features that confer selectivity.
Grace Q Gong, Jackie D Kendall, James M J Dickson, Gordon W Rewcastle, Christina M Buchanan

Biochem J· June 2017

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Expression of IL-17 and syndecan-1 in nasal polyps and their correlation with nasal polyps.
Guo-Qing Gong, Fang-Fang Ren, Yan-Jun Wang, Lang Wan, Shan Chen

J Huazhong Univ Sci Technolog Med Sci· June 2017

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Evaluating antithrombotic activity of HY023016 on rat hypercoagulable model.
Qiu-Fang Chen, Yun-Zhan Li, Xin-Hui Wang, You-Rui Su, Shuang Cui, Guo-Qing Gong

Eur J Pharmacol· June 2016

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Antidepressant-like effect of evodiamine on chronic unpredictable mild stress rats.
Mei-Ling Jiang, Zhi-Xian Zhang, Yun-Zhan Li, Xin-Hui Wang, Wei Yan, Guo-Qing Gong

Neurosci Lett· February 2015

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Transarterial infusion with gemcitabine and oxaliplatin for the treatment of unresectable pancreatic cancer.
Yi Chen, Xiao-Lin Wang, Jian-Hua Wang, Zhi-Ping Yan, Jie-Min Cheng, Gao-Quan Gong

Anticancer Drugs· September 2014

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NLRP3 inflammasome sequential changes in Staphylococcus aureus-induced mouse model of acute rhinosinusitis.
Yan-Jun Wang, Guo-Qing Gong, Shan Chen, Li-Yan Xiong, Xing-Xing Zhou

Int J Mol Sci· September 2014

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Effects of IL-17 on expression of GRO-α and IL-8 in fibroblasts from nasal polyps.
Yong-Zhi Niu, Guo-Qing Gong, Shan Chen, Jian-Jun Chen, Wei-Jia Kong

J Huazhong Univ Sci Technolog Med Sci· August 2014

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Fine needle aspirating and cutting is superior to Tru-cut core needle in liver biopsy.
Guo-Ping Li, Gao-Quan Gong, Xiao-Lin Wang, Yi Chen, Jie-Min Cheng

Hepatobiliary Pancreat Dis Int· October 2013

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Antithrombotic activity of HY023016, a novel Dabigatran prodrug evaluated in animal thrombosis models.
Yun-Zhan Li, Guo-Qing Gong, Wen-Hui Yang, Xin-Hui Wang, Mei-Ling Jiang

Thromb Res· May 2013

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Design, synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing methyl ferulate.
Xiao-Zhi Yang, Xiao-Juan Diao, Wen-Hui Yang, Feng Li, Guang-Wei He, Guo-Qing Gong

Bioorg Med Chem Lett· April 2013

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