Publications by authors named "Gabriel Boyle"

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Evidence for variant classification from multiplexed functional assays.
Renee C Geck, Melinda K Wheelock, Rachel L Powell, Ziyu R Wang, Daniel L Holmes, Gabriel E Boyle

bioRxiv· November 2025

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The length of the G1 phase is an essential determinant of H3K27me3 landscapes across diverse cell types.
Abby Trouth, Kameswaran Ravichandran, Philip R Gafken, Sara Martire, Gabriel E Boyle

PLoS Biol· April 2025

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Deep mutational scanning of CYP2C19 in human cells reveals a substrate specificity-abundance tradeoff.
Gabriel E Boyle, Katherine A Sitko, Jared G Galloway, Hugh K Haddox, Aisha Haley Bianchi

Genetics· November 2024

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G1 length dictates H3K27me3 landscapes.
Abby Trouth, Kamesh Ravichandran, Philip R Gafken, Sara Martire, Gabriel E Boyle

bioRxiv· August 2024

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Correction: SNCA genetic lowering reveals differential cognitive function of alpha-synuclein dependent on sex.
Jennifer L Brown, Damyan W Hart, Gabriel E Boyle, Taylor G Brown, Michael LaCroix

Acta Neuropathol Commun· June 2024

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Pacybara: accurate long-read sequencing for barcoded mutagenized allelic libraries.
Jochen Weile, Gabrielle Ferra, Gabriel Boyle, Sriram Pendyala, Clara Amorosi

Bioinformatics· March 2024

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Pacybara: Accurate long-read sequencing for barcoded mutagenized allelic libraries.
Jochen Weile, Gabrielle Ferra, Gabriel Boyle, Sriram Pendyala, Clara Amorosi

bioRxiv· December 2023

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SNCA genetic lowering reveals differential cognitive function of alpha-synuclein dependent on sex.
Jennifer L Brown, Damyan W Hart, Gabriel E Boyle, Taylor G Brown, Michael LaCroix

Acta Neuropathol Commun· December 2022

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Measuring Pharmacogene Variant Function at Scale Using Multiplexed Assays.
Renee C Geck, Gabriel Boyle, Clara J Amorosi, Douglas M Fowler, Maitreya J Dunham

Annu Rev Pharmacol Toxicol· January 2022

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Massively parallel characterization of CYP2C9 variant enzyme activity and abundance.
Clara J Amorosi, Melissa A Chiasson, Matthew G McDonald, Lai Hong Wong, Katherine A Sitko, Gabriel Boyle

Am J Hum Genet· September 2021

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Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons.
Shahzad S Khan, Michael LaCroix, Gabriel Boyle, Mathew A Sherman, Jennifer L Brown

Acta Neuropathol· October 2018

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Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.
Megan E Larson, Susan J Greimel, Fatou Amar, Michael LaCroix, Gabriel Boyle

Proc Natl Acad Sci U S A· June 2017

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The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation.
Fatou Amar, Mathew A Sherman, Travis Rush, Megan Larson, Gabriel Boyle

Sci Signal· May 2017

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