Publications by authors named "Gaia Faustini"

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Experimental Ischemic Stroke-Induced Alpha-Synuclein Pathology Enhances Endothelial Inflammatory Response and Impairs Angiogenesis.
Tizibt Ashine Bogale, Domenico Mercurio, Alessia Valente, Serena Seminara, Gaia Faustini

Stroke· December 2025

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A novel stable transgenic zebrafish line expressing mCherry-tagged human alpha-synuclein in the nervous system and exhibiting all the key features of Lewy body disorders at larval stage.
Silvia Zini, Alessia Muscò, Francesca Longhena, Gaia Faustini, Chiara Tobia

Neurobiol Dis· September 2025

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Lewy pathology formation in patient-derived GBA1 Parkinson's disease midbrain organoids.
Emanuele Frattini, Gaia Faustini, Gianluca Lopez, Emma Veronica Carsana, Mattia Tosi

Brain· April 2025

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Early α-synuclein/synapsin III co-accumulation, nigrostriatal dopaminergic synaptopathy and denervation in the MPTPp mouse model of Parkinson's Disease.
Marcello Serra, Gaia Faustini, Viviana Brembati, Maria Antonietta Casu, Marina Pizzi

Exp Neurol· January 2025

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Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson's Disease.
Viviana Brembati, Gaia Faustini, Francesca Longhena, Tiago Fleming Outeiro, Arianna Bellucci

Int J Mol Sci· August 2023

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Alpha synuclein post translational modifications: potential targets for Parkinson's disease therapy?
Viviana Brembati, Gaia Faustini, Francesca Longhena, Arianna Bellucci

Front Mol Neurosci· May 2023

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DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease.
Anna Masato, Nicoletta Plotegher, Francesca Terrin, Michele Sandre, Gaia Faustini

NPJ Parkinsons Dis· March 2023

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Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates.
Gaia Faustini, Francesca Longhena, Alessia Muscò, Federica Bono, Edoardo Parrella

Cells· December 2022

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Corrigendum: Design and Synthesis of Fluorescent Methylphenidate Analogues for a FRET-Based Assay of Synapsin III Binding.
Andrea Casiraghi, Francesca Longhena, Valentina Straniero, Gaia Faustini, Amy H Newman

ChemMedChem· July 2022

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Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson's Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice.
Andrea Casiraghi, Francesca Longhena, Gaia Faustini, Giovanni Ribaudo, Lorenzo Suigo

Pharmaceutics· July 2022

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Alpha-Synuclein is Involved in DYT1 Dystonia Striatal Synaptic Dysfunction.
Giulia Ponterio, Gaia Faustini, Ilham El Atiallah, Giuseppe Sciamanna, Maria Meringolo

Mov Disord· May 2022

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Synapsin III gene silencing redeems alpha-synuclein transgenic mice from Parkinson's disease-like phenotype.
Gaia Faustini, Francesca Longhena, Anna Masato, Valentina Bassareo, Roberto Frau

Mol Ther· April 2022

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Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson's disease.
Adrianne F Pike, Francesca Longhena, Gaia Faustini, Jean-Marc van Eik, Iris Gombert

J Neuroinflammation· February 2022

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An updated reappraisal of synapsins: structure, function and role in neurological and psychiatric disorders.
Francesca Longhena, Gaia Faustini, Viviana Brembati, Marina Pizzi, Fabio Benfenati

Neurosci Biobehav Rev· November 2021

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The Association between α-Synuclein and α-Tubulin in Brain Synapses.
Alida Amadeo, Sara Pizzi, Alessandro Comincini, Debora Modena, Alessandra Maria Calogero, Gaia Faustini

Int J Mol Sci· August 2021

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Alpha-Synuclein in the Regulation of Brain Endothelial and Perivascular Cells: Gaps and Future Perspectives.
Tizibt Ashine Bogale, Gaia Faustini, Francesca Longhena, Stefania Mitola, Marina Pizzi

Front Immunol· June 2021

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Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes.
Alice Filippini, Veronica Mutti, Gaia Faustini, Francesca Longhena, Ileana Ramazzina

Glia· March 2021

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Design and Synthesis of Fluorescent Methylphenidate Analogues for a FRET-Based Assay of Synapsin III Binding.
Andrea Casiraghi, Francesca Longhena, Valentina Straniero, Gaia Faustini, Amy H Newman

ChemMedChem· July 2020

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Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal Cells.
Gaia Faustini, Elena Marchesan, Laura Zonta, Federica Bono, Emanuela Bottani

Oxid Med Cell Longev· May 2020

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Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate.
Gaia Faustini, Francesca Longhena, Agostino Bruno, Federica Bono, Jessica Grigoletto

Neurobiol Dis· May 2020

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The good and bad of therapeutic strategies that directly target α-synuclein.
Francesca Longhena, Gaia Faustini, Viviana Brembati, Marina Pizzi, Arianna Bellucci

IUBMB Life· April 2020

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Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson's Disease.
Arianna Bellucci, Luigi Bubacco, Francesca Longhena, Edoardo Parrella, Gaia Faustini

Front Aging Neurosci· March 2020

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Study of alpha-synuclein fibrillation: state of the art and expectations.
Francesca Longhena, Gaia Faustini, Arianna Bellucci

Neural Regen Res· January 2020

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NF-κB/c-Rel deficiency causes Parkinson's disease-like prodromal symptoms and progressive pathology in mice.
Edoardo Parrella, Arianna Bellucci, Vanessa Porrini, Marina Benarese, Annamaria Lanzillotta, Gaia Faustini

Transl Neurodegener· May 2019

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Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology.
Francesca Longhena, Gaia Faustini, Maria Grazia Spillantini, Arianna Bellucci

Int J Mol Sci· January 2019

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