Publications by authors named "Gajanan D Katkar"

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Distinct colitis-associated macrophages drive NOD2-dependent bacterial sensing and gut homeostasis.
Gajanan D Katkar, Mahitha Shree Anandachar, Stella-Rita C Ibeawuchi, Ella G McLaren, Megan L Estanol

J Clin Invest· December 2025

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Distinct Colitis-Associated Macrophages Drive NOD2-Dependent Bacterial Sensing and Gut Homeostasis.
Gajanan D Katkar, Mahitha Shree Anandachar, Stella-Rita Ibeawuchi, Ella McLaren, Megan Estanol

bioRxiv· July 2025

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A living organoid biobank of patients with Crohn's disease reveals molecular subtypes for personalized therapeutics.
Courtney Tindle, Ayden G Fonseca, Sahar Taheri, Gajanan D Katkar, Jasper Lee

Cell Rep Med· October 2024

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Diverse gut pathogens exploit the host engulfment pathway via a conserved mechanism.
Mahitha Shree Anandachar, Suchismita Roy, Saptarshi Sinha, Agyekum Boadi, Gajanan D Katkar

J Biol Chem· December 2023

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Diverse Gut Pathogens Exploit the Host Engulfment Pathway via a Conserved Mechanism.
Mahitha Shree Anandachar, Suchismita Roy, Saptarshi Sinha, Boadi Agyekum, Stella-Rita Ibeawuchi, Gajanan Dattatray Katkar

bioRxiv· August 2023

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Machine learning identifies signatures of macrophage reactivity and tolerance that predict disease outcomes.
Pradipta Ghosh, Saptarshi Sinha, Gajanan D Katkar, Daniella Vo, Sahar Taheri

EBioMedicine· August 2023

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A Living Organoid Biobank of Crohn's Disease Patients Reveals Molecular Subtypes for Personalized Therapeutics.
Courtney Tindle, Gajanan D Katkar, Ayden G Fonseca, Sahar Taheri, Jasper Lee

bioRxiv· March 2023

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COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.
Saptarshi Sinha, Vanessa Castillo, Celia R Espinoza, Courtney Tindle, Ayden G Fonseca, Gajanan D Katkar

EBioMedicine· August 2022

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Publisher Correction: An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease.
Pradipta Ghosh, Gajanan D Katkar, Chisato Shimizu, Jihoon Kim, Soni Khandelwal

Nat Commun· August 2022

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COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.
Saptarshi Sinha, Vanessa Castillo, Celia R Espinoza, Courtney Tindle, Ayden G Fonseca, Gajanan D Katkar

bioRxiv· July 2022

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An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease.
Pradipta Ghosh, Gajanan D Katkar, Chisato Shimizu, Jihoon Kim, Soni Khandelwal

Nat Commun· May 2022

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Artificial intelligence-rationalized balanced PPARα/γ dual agonism resets dysregulated macrophage processes in inflammatory bowel disease.
Gajanan D Katkar, Ibrahim M Sayed, Mahitha Shree Anandachar, Vanessa Castillo, Eleadah Vidales

Commun Biol· March 2022

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Parsing the Role of PPARs in Macrophage Processes.
Daniel Toobian, Pradipta Ghosh, Gajanan D Katkar

Front Immunol· February 2022

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A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1,2,4-triazoles.
Muhamad Mustafa, Amer Ali Abd El-Hafeez, Dalia Abdelhamid, Gajanan D Katkar, Yaser A Mostafa

Eur J Med Chem· October 2021

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An AI-guided signature reveals the nature of the shared proximal pathways of host immune response in MIS-C and Kawasaki disease.
Debashis Sahoo, Gajanan D Katkar, Chisato Shimizu, Jihoon Kim, Soni Khandelwal

bioRxiv· August 2021

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GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility.
Sequoyah Reynoso, Vanessa Castillo, Gajanan Dattatray Katkar, Inmaculada Lopez-Sanchez, Sahar Taheri

Elife· August 2021

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Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19.
Courtney Tindle, MacKenzie Fuller, Ayden Fonseca, Sahar Taheri, Stella-Rita Ibeawuchi, Gajanan Dattatray Katkar

Elife· August 2021

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Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease.
Debashis Sahoo, Lee Swanson, Ibrahim M Sayed, Gajanan D Katkar, Stella-Rita Ibeawuchi

Nat Commun· July 2021

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Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides.
Elke M Muntjewerff, Kechun Tang, Lisanne Lutter, Gustaf Christoffersson, Mara J T Nicolasen, Gajanan D Katkar

Acta Physiol (Oxf)· June 2021

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AI-guided discovery of the invariant host response to viral pandemics.
Debashis Sahoo, Gajanan D Katkar, Soni Khandelwal, Mahdi Behroozikhah, Amanraj Claire

EBioMedicine· June 2021

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AI-guided discovery of the invariant host response to viral pandemics.
Debashis Sahoo, Gajanan D Katkar, Soni Khandelwal, Mahdi Behroozikhah, Amanraj Claire

bioRxiv· April 2021

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TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin.
Lee Swanson, Gajanan D Katkar, Julian Tam, Rama F Pranadinata, Yogitha Chareddy

Proc Natl Acad Sci U S A· October 2020

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Research into the Causes of Venom-Induced Mortality and Morbidity Identifies New Therapeutic Opportunities.
Kesturu S Girish, Gajanan D Katkar, Robert A Harrison, Kempaiah Kemparaju

Am J Trop Med Hyg· May 2019

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Reply to 'Evidence that neutrophils do not promote Echis carinatus venom-induced tissue destruction'.
Kempaiah Kemparaju, Kesturu S Girish, Gajanan D Katkar

Nat Commun· June 2018

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Inhibition of Echis carinatus venom by DNA, a promising therapeutic molecule for snakebite management.
Basavarajaiah Swethakumar, Somanathapura K NaveenKumar, Gajanan D Katkar, Kesturu S Girish, Kempaiah Kemparaju

Biochim Biophys Acta Gen Subj· May 2018

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