Publications by authors named "Ganesh Raj"

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CDK4/6 inhibitors promote PARP1 degradation and synergize with PARP inhibitors in non-small cell lung cancer.
Carlos M Roggero, Anwesha B Ghosh, Anvita Devineni, Shihong Ma, Eliot Blatt, Ganesh V Raj

Transl Oncol· February 2025

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ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer.
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjöström, Yuyin Jiang, Ganesh V Raj

Cancer Discov· August 2024

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CDK4/6 inhibitors promote PARP1 degradation and act synergistically with PARP inhibitors in non-small cell lung cancer.
Carlos M Roggero, Anwesha B Ghosh, Anvita Devineni, Shihong Ma, Eliot Blatt, Ganesh V Raj

bioRxiv· July 2024

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Author Correction: Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress.
Xihui Liu, Suryavathi Viswanadhapalli, Shourya Kumar, Tae-Kyung Lee, Andrew Moore, Rajeshwar R Tekmal, Ganesh V Raj

Nat Cancer· June 2024

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Oligo-benzamide-based peptide mimicking tools for modulating biology.
Chia-Yuan Chen, Scott Elmore, Ismail Lalami, Henry Neal, Ratna K Vadlamudi, Ganesh V Raj

Methods Enzymol· June 2024

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Evaluating physiochemical properties of FDA-approved orally administered drugs.
Tanner C Reese, Anvita Devineni, Tristan Smith, Ismail Lalami, Jung-Mo Ahn, Ganesh V Raj

Expert Opin Drug Discov· February 2024

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UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistance.
Carla Rodriguez Tirado, Choushi Wang, Xiaoling Li, Su Deng, Julisa Gonzalez, Medha Sundar Rajan, Ganesh V Raj

Oncogene· January 2024

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Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.
Giacomo Grillo, Tina Keshavarzian, Simon Linder, Christopher Arlidge, Lisanne Mout, Ganesh V Raj

Cancer Discov· November 2023

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ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers.
Yaru Xu, Zhaoning Wang, Martin Sjöström, Su Deng, Choushi Wang, Ganesh Raj

bioRxiv· October 2023

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Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer.
Xiaoling Li, Yunguan Wang, Su Deng, Guanghui Zhu, Choushi Wang, Ganesh Raj

Cancer Cell· August 2023

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Riluzole Suppresses Growth and Enhances Response to Endocrine Therapy in ER+ Breast Cancer.
Ayodeji O Olukoya, Hillary Stires, Shaymaa Bahnassy, Sonali Persaud, Yanira Guerra, Ganesh V Raj

J Endocr Soc· August 2023

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Critical role of antioxidant programs in enzalutamide-resistant prostate cancer.
Eliot B Blatt, Karla Parra, Antje Neeb, Lorenzo Buroni, Denisa Bogdan, Ganesh V Raj

Oncogene· July 2023

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Testosterone and the Androgen Receptor.
Thomas Gerald, Ganesh Raj

Urol Clin North Am· November 2022

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Enrichment of "Cribriform" morphologies (intraductal and cribriform adenocarcinoma) and genomic alterations in radiorecurrent prostate cancer.
Rajal B Shah, Doreen N Palsgrove, Neil B Desai, Jeffrey Gagan, Amanda Mennie, Ganesh Raj

Mod Pathol· October 2022

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A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer.
Kristin A Altwegg, Suryavathi Viswanadhapalli, Monica Mann, Dimple Chakravarty, Samaya Krishnan, Ganesh V Raj, Rajeshwar R Tekmal

Cancer Res· October 2022

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Author Correction: Ectopic JAK-STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance.
Su Deng, Choushi Wang, Yunguan Wang, Yaru Xu, Xiaoling Li, Ganesh Raj

Nat Cancer· October 2022

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Targeting ESR1 mutation-induced transcriptional addiction in breast cancer with BET inhibition.
Sm N Udden, Qian Wang, Sunil Kumar, Venkat S Malladi, Shwu-Yuan Wu, Ganesh V Raj

JCI Insight· September 2022

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Emerging hormonal agents for the treatment of prostate cancer.
Emily Bochner, Sam Gold, Ganesh V Raj

Expert Opin Emerg Drugs· September 2022

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Ectopic JAK-STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance.
Su Deng, Choushi Wang, Yunguan Wang, Yaru Xu, Xiaoling Li, Ganesh Raj

Nat Cancer· September 2022

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Alterations in BRCA2 as Determinants of Therapy Response in Prostate Cancer.
Mia Hofstad, Emily Y Huang, Andrea Woods, Yi Yin, Neil B Desai, Ganesh V Raj

Crit Rev Oncog· August 2022

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Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress.
Xihui Liu, Suryavathi Viswanadhapalli, Shourya Kumar, Tae-Kyung Lee, Andrew Moore, Rajeshwar R Tekmal, Ganesh V Raj

Nat Cancer· July 2022

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Targeting radioresistance and replication fork stability in prostate cancer.
Xiangyi Li, GuemHee Baek, Suzanne Carreira, Wei Yuan, Shihong Ma, Ganesh V Raj

JCI Insight· May 2022

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Poly-glutamine-dependent self-association as a potential mechanism for regulation of androgen receptor activity.
Carlos M Roggero, Victoria Esser, Lingling Duan, Allyson M Rice, Shihong Ma, Ganesh V Raj

PLoS One· February 2022

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The central role of Sphingosine kinase 1 in the development of neuroendocrine prostate cancer (NEPC): A new targeted therapy of NEPC.
Cheng-Fan Lee, Yu-An Chen, Elizabeth Hernandez, Rey-Chen Pong, Shihong Ma, Ganesh V Raj

Clin Transl Med· February 2022

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Dose-Intensified Stereotactic Ablative Radiation for Localized Prostate Cancer.
Lily Chen, Bhavani S Gannavarapu, Neil B Desai, Michael R Folkert, Michael Dohopolski, Ganesh V Raj

Front Oncol· February 2022

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