Publications by authors named "Gaopeng Song"

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Discovery and optimization of OA amide derivatives containing a trisubstituted l-hydroxyproline fragment as novel Omicron fusion inhibitors.
Chongjun Hong, Hao Su, Long Lu, Xiaoxuan Cui, Xin Wan, Gaopeng Song

Eur J Med Chem· December 2025

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A novel C-3-substituted oleanolic acid benzyl amide derivative exhibits therapeutic potential against influenza A by targeting PA-PB1 interactions and modulating host macrophage inflammation.
Kunyu Lu, Jianfu He, Chongjun Hong, Haowei Li, Jiaai Ruan, Gaopeng Song

Acta Pharm Sin B· August 2025

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Design and Synthesis of Aryl Amide Derivatives Containing Thiazole as Type III Secretion System Inhibitors against .
Mingming Guan, Di Zhu, Junjie Wei, Zhe He, Lan-Tu Xiong, Gaopeng Song

J Agric Food Chem· August 2024

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Optimization and biological evaluation of l-DOPA derivatives as potent influenza PA endonuclease inhibitors with multi-site binding characteristics.
Jiaai Ruan, Kunyu Lu, Jianfu He, Yihao Chen, Baixi Li, Gaopeng Song

Bioorg Chem· March 2024

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Derivative of cinnamic acid inhibits T3SS of Xanthomonas oryzae pv. oryzae through the HrpG-HrpX regulatory cascade.
Yu Shi, Lan-Tu Xiong, Hui Li, Wen-Long Li, Dylan O'Neill Rothenberg, Gao-Peng Song

Bioorg Chem· December 2023

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Optimization, and biological evaluation of 3-O-β-chacotriosyl betulinic acid amide derivatives as novel small-molecule Omicron.
Mingjian Liu, Jinshen Wang, Shanshan Shi, Yongfeng Gao, Yixiao Zhang, Gaopeng Song

Eur J Med Chem· August 2023

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Kunxian capsule alleviates renal damage by inhibiting the JAK1/STAT1 pathway in lupus nephritis.
Chen Cheng, Rongrong Zhu, Mingjian Liu, Hao Yang, Fangfang Guo, Gaopeng Song

J Ethnopharmacol· June 2023

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Novel Ethyl-3-Aryl-2-Nitroacrylate Derivatives as Potential T3SS Inhibitors against pv. on Rice.
Dongni Gao, Hui Li, Jiang Shao, Lulu He, Chen Fu, Gaopeng Song

J Agric Food Chem· June 2023

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Discovery and structural optimization of 3-O-β-Chacotriosyl betulonic acid saponins as potent fusion inhibitors of Omicron virus infections.
Mingjian Liu, Jinshen Wang, Xin Wan, Baixi Li, Mingming Guan, Gaopeng Song

Bioorg Chem· February 2023

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Identification of N- and C-3-Modified Laudanosoline Derivatives as Novel Influenza PA Endonuclease Inhibitors.
Yixian Liao, Yilu Ye, Mingjian Liu, Zhihao Liu, Jinshen Wang, Gaopeng Song

J Med Chem· January 2023

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Identification, optimization, and biological evaluation of 3-O-β-chacotriosyl ursolic acid derivatives as novel SARS-CoV-2 entry inhibitors by targeting the prefusion state of spike protein.
Hui Li, Chen Cheng, Shanshan Shi, Yan Wu, Yongfeng Gao, Gaopeng Song

Eur J Med Chem· August 2022

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Toosendanin activates caspase-1 and induces maturation of IL-1β to inhibit type 2 porcine reproductive and respiratory syndrome virus replication via an IFI16-dependent pathway.
Mingxin Zhang, Chunni Lu, Lizhan Su, Feixiang Long, Xia Yang, Gaopeng Song

Vet Res· July 2022

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Phosphodiesterase‑4 inhibitors: a review of current developments (2013-2021).
Zhihao Liu, Mingjian Liu, Zhenqing Cao, Pengsen Qiu, Gaopeng Song

Expert Opin Ther Pat· March 2022

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Diversity-Oriented Synthesis of Fluoromethylated Arenes via Palladium-Catalyzed C-H Fluoromethylation of Aryl Iodides.
Yiming Du, Shuxin Chen, Ao Huang, Yihan Chen, Yun-Lin Liu, Gaopeng Song

Org Lett· February 2022

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The Potential Binding Interaction and Hydrolytic Mechanism of Carbaryl with the Novel Esterase PchA in sp. PS21.
Zhiyan Jiang, Liwen Qu, Gaopeng Song, Jie Liu, Guohua Zhong

J Agric Food Chem· February 2022

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Discovery and optimization of new 6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline derivatives as potent influenza virus PA inhibitors.
Zhihao Liu, Shuyin Gu, Xiang Zhu, Mingjian Liu, Zhenqing Cao, Gaopeng Song

Eur J Med Chem· January 2022

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Discovery and structural optimization of 3-O-β-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections.
Hui Li, Chen Cheng, Sumei Li, Yan Wu, Zhihao Liu, Gaopeng Song

Eur J Med Chem· April 2021

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Structure-aided optimization of 3-O-β-chacotriosyl epiursolic acid derivatives as novel H5N1 virus entry inhibitors.
Sumei Li, Xiuhua Jia, Hui Li, Yilu Ye, Xuesha Zhang, Gaopeng Song

Bioorg Med Chem Lett· November 2020

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Ursolic acid derivatives are potent inhibitors against porcine reproductive and respiratory syndrome virus.
Yang Chen, Hui Li, Li Wu, Mingxin Zhang, Yarou Gao, Gaopeng Song

RSC Adv· June 2020

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Synthesis and SARs of dopamine derivatives as potential inhibitors of influenza virus PA endonuclease.
Yixian Liao, Yilu Ye, Sumei Li, Yilian Zhuang, Liye Chen, Gaopeng Song

Eur J Med Chem· March 2020

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Study on the Antiviral Activities and Hemagglutinin-Based Molecular Mechanism of Novel Chlorogenin 3--β-Chacotrioside Derivatives Against H5N1 Subtype Viruses.
Wan-Zhen Shi, Ling-Zhi Jiang, Gao-Peng Song, Sheng Wang, Ping Xiong

Viruses· March 2020

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An Oleanolic Acid Derivative Inhibits Hemagglutinin-Mediated Entry of Influenza A Virus.
Mengdie Ye, Yixian Liao, Li Wu, Wenbao Qi, Namrta Choudhry, Gaopeng Song

Viruses· February 2020

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Discovery of novel inhibitors of phosphodiesterase 4 with 1-phenyl-3,4-dihydroisoquinoline scaffold: Structure-based drug design and fragment identification.
Yixian Liao, Xiuhua Jia, Yongmei Tang, Sumei Li, Yipeng Zang, Gaopeng Song

Bioorg Med Chem Lett· November 2019

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Incorporation of privileged structures into 3-O-β-chacotriosyl ursolic acid can enhance inhibiting the entry of the H5N1 virus.
Hui Li, Lizhu Chen, Sumei Li, Yixian Liao, Lei Wang, Gaopeng Song

Bioorg Med Chem Lett· September 2019

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Discovery of Ethyl 2-Nitro-3-Arylacrylates Molecules as T3SS Inhibitor Reducing the Virulence of Plant Pathogenic Bacteria .
Shan Jiang, Hui Li, Wasim Ahmed, Xuwen Xiang, Gaopeng Song

Front Microbiol· August 2019

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