Publications by authors named "Gaoxin Lei"

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Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy.
Menglong Xu, Gaoxin Lei, Manman Chen, Ke Wang, Wenxiu Lv

EBioMedicine· March 2021

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Lunasin Improves the LDL-C Lowering Efficacy of Simvastatin via Inhibiting PCSK9 Expression in Hepatocytes and ApoE Mice.
Lili Gu, Yaqin Gong, Cheng Zhao, Yue Wang, Qinghua Tian, Gaoxin Lei

Molecules· November 2019

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Lunasin attenuates oxidant-induced endothelial injury and inhibits atherosclerotic plaque progression in ApoE mice by up-regulating heme oxygenase-1 via PI3K/Akt/Nrf2/ARE pathway.
Lili Gu, Pei Ye, Hengli Li, Yue Wang, Yaqiong Xu, Gaoxin Lei

FASEB J· April 2019

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Combination of novel DR5 targeting agonistic scFv antibody TR2-3 with cisplatin shows enhanced synergistic antitumor activity in vitro and in vivo.
Gaoxin Lei, Menglong Xu, Zhipan Xu, Chenchen Lu, Shuhua Tan

Biomed Pharmacother· February 2018

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Lunasin functionally enhances LDL uptake via inhibiting PCSK9 and enhancing LDLR expression and .
Lili Gu, Yue Wang, Yaqiong Xu, Qinghua Tian, Gaoxin Lei

Oncotarget· October 2017

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A Novel Fully Human Agonistic Single Chain Fragment Variable Antibody Targeting Death Receptor 5 with Potent Antitumor Activity In Vitro and In Vivo.
Gaoxin Lei, Menglong Xu, Zhipan Xu, Lili Gu, Chenchen Lu

Int J Mol Sci· September 2017

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