Publications by authors named "Gareth S D Purvis"

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Retraction Note: Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes.
Gareth S D Purvis, Fausto Chiazza, Jianmin Chen, Rodrigo Azevedo-Loiola, Lukas Martin

Diabetologia· July 2025

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Correction: RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance.
Jianmin Chen, Gareth S D Purvis, Debora Collotta, Sura Ai Zoubi, Michelle A Sugimoto

Front Immunol· July 2025

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Ly6C Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation.
Gareth S D Purvis, Eileen McNeill, Benjamin Wright, Keith M Channon, David R Greaves

Cells· May 2024

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OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity.
Gareth S D Purvis, Massimo Collino, Andrea D van Dam, Giacomo Einaudi, Yujung Ng

Diabetes· January 2024

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A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages.
Agata N Rumianek, Ben Davies, Keith M Channon, David R Greaves, Gareth S D Purvis

Front Immunol· July 2022

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Bruton's TK regulates myeloid cell recruitment during acute inflammation.
Gareth S D Purvis, Haidee Aranda-Tavio, Keith M Channon, David R Greaves

Br J Pharmacol· June 2022

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Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood-brain barrier: Therapeutic avenues.
Madeeha H Sheikh, Mariella Errede, Antonio d'Amati, Noorafza Q Khan, Silvia Fanti, Gareth S D Purvis

FASEB J· January 2022

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A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice.
Shireen Mohammad, Sura Al Zoubi, Debora Collotta, Nadine Krieg, Bianka Wissuwa, Gareth S D Purvis

Front Immunol· December 2021

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X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure.
Caroline E O'Riordan, Gareth S D Purvis, Debora Collotta, Nadine Krieg, Bianka Wissuwa

Front Immunol· June 2021

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RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance.
Jianmin Chen, Gareth S D Purvis, Debora Collotta, Sura Al Zoubi, Michelle A Sugimoto

Front Immunol· April 2021

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Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.
Caroline E O'Riordan, Gareth S D Purvis, Debora Collotta, Fausto Chiazza, Bianka Wissuwa

Front Immunol· October 2020

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Inhibition of Bruton's TK regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation.
Gareth S D Purvis, Massimo Collino, Haidee Aranda-Tavio, Fausto Chiazza, Caroline E O'Riordan

Br J Pharmacol· October 2020

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Annexin-A1: Therapeutic Potential in Microvascular Disease.
Gareth S D Purvis, Egle Solito, Christoph Thiemermann

Front Immunol· September 2020

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Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes.
Gareth S D Purvis, Massimo Collino, Rodrigo A Loiola, Andrea Baragetti, Fausto Chiazza

Front Immunol· July 2020

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A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages.
Daniel Lucy, Gareth S D Purvis, Lynda Zeboudj, Maria Chatzopoulou, Carlota Recio

ACS Chem Biol· September 2019

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Efferocytosis perpetuates substance accumulation inside macrophage populations.
Hugh Z Ford, Lynda Zeboudj, Gareth S D Purvis, Annemieke Ten Bokum, Alexander E Zarebski

Proc Biol Sci· June 2019

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Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock.
Noriaki Yamada, Lukas B Martin, Elisabeth Zechendorf, Gareth S D Purvis, Fausto Chiazza

Ann Surg· August 2018

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Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages.
Carlota Recio, Daniel Lucy, Gareth S D Purvis, Poppy Iveson, Lynda Zeboudj

Front Immunol· June 2018

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Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes.
Gareth S D Purvis, Fausto Chiazza, Jianmin Chen, Rodrigo Azevedo-Loiola, Lukas Martin

Diabetologia· February 2018

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Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis.
Florence L Johnson, Nimesh S A Patel, Gareth S D Purvis, Fausto Chiazza, Jianmin Chen

J Am Heart Assoc· July 2017

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IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD.
Jianmin Chen, Julius E Kieswich, Fausto Chiazza, Amie J Moyes, Thomas Gobbetti, Gareth S D Purvis

J Am Soc Nephrol· January 2017

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