Publications by authors named "Garret Hampton"

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Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).
Marcin Kowanetz, Wei Zou, Scott N Gettinger, Hartmut Koeppen, Mark Kockx, Garret Hampton

Proc Natl Acad Sci U S A· October 2018

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A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types.
Marie-Claire Wagle, Daniel Kirouac, Christiaan Klijn, Bonnie Liu, Shilpi Mahajan, Garret Hampton

NPJ Precis Oncol· March 2018

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Development and Application of a Microfluidics-Based Panel in the Basal/Luminal Transcriptional Characterization of Archival Bladder Cancers.
Doris Kim, YounJeong Choi, James Ireland, Oded Foreman, Rachel N Tam, Garret M Hampton

PLoS One· June 2017

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The molecular landscape of high-risk early breast cancer: comprehensive biomarker analysis of a phase III adjuvant population.
Timothy R Wilson, Jianjun Yu, Xuyang Lu, Jill M Spoerke, Yuanyuan Xiao, Garret M Hampton

NPJ Breast Cancer· July 2016

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Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant.
Jill M Spoerke, Steven Gendreau, Kimberly Walter, Jiaheng Qiu, Timothy R Wilson, Garret M Hampton

Nat Commun· May 2016

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Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110β.
Yoshito Nakanishi, Kimberly Walter, Jill M Spoerke, Carol O'Brien, Ling Y Huw, Garret M Hampton

Cancer Res· March 2016

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Development of a robust RNA-based classifier to accurately determine ER, PR, and HER2 status in breast cancer clinical samples.
Timothy R Wilson, Yuanyuan Xiao, Jill M Spoerke, Jane Fridlyand, Hartmut Koeppen, Garret M Hampton

Breast Cancer Res Treat· November 2014

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Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers.
Erica B Schleifman, Rupal Desai, Jill M Spoerke, Yuanyuan Xiao, Cheryl Wong, Garret M Hampton

PLoS One· October 2014

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High-throughput detection of clinically relevant mutations in archived tumor samples by multiplexed PCR and next-generation sequencing.
Richard Bourgon, Shan Lu, Yibing Yan, Mark R Lackner, Weiru Wang, Garret M Hampton

Clin Cancer Res· April 2014

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Profiling cancer gene mutations in clinical formalin-fixed, paraffin-embedded colorectal tumor specimens using targeted next-generation sequencing.
Liangxuan Zhang, Liangjing Chen, Sachin Sah, Gary J Latham, Rajesh Patel, Garret M Hampton

Oncologist· April 2014

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Discovery and development of DNA methylation-based biomarkers for lung cancer.
Kimberly Walter, Thomas Holcomb, Tom Januario, Robert L Yauch, Pan Du, Garret M Hampton

Epigenomics· February 2014

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Evaluation and clinical analyses of downstream targets of the Akt inhibitor GDC-0068.
Yibing Yan, Violeta Serra, Ludmila Prudkin, Maurizio Scaltriti, Sumati Murli, Garret Hampton

Clin Cancer Res· December 2013

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High heregulin expression is associated with activated HER3 and may define an actionable biomarker in patients with squamous cell carcinomas of the head and neck.
David S Shames, Juliet Carbon, Kim Walter, Adrian M Jubb, Cleopatra Kozlowski, Garret M Hampton

PLoS One· August 2013

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HGF as a circulating biomarker of onartuzumab treatment in patients with advanced solid tumors.
Elicia Penuel, Congfen Li, Vaishali Parab, Luciana Burton, Kyra J Cowan, Garret M Hampton

Mol Cancer Ther· June 2013

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Development of a robust flow cytometry-based pharmacodynamic assay to detect phospho-protein signals for phosphatidylinositol 3-kinase inhibitors in multiple myeloma.
Congfen Li, Chikara Takahashi, Liangxuan Zhang, Mahrukh Huseni, Basha Stankovich, Garret Hampton

J Transl Med· March 2013

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Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary.
Dirk Bauerschlag, Karen Bräutigam, Roland Moll, Jalid Sehouli, Alexander Mustea, Garret M Hampton

J Cancer Res Clin Oncol· February 2013

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Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models.
Jill M Spoerke, Carol O'Brien, Ling Huw, Hartmut Koeppen, Jane Fridlyand, Garret M Hampton

Clin Cancer Res· December 2012

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Prostate cancer - a biomarker perspective.
Yanqiu Liu, Priti Hegde, Fengmin Zhang, Garret Hampton, Shidong Jia

Front Endocrinol (Lausanne)· July 2012

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ERK inhibition overcomes acquired resistance to MEK inhibitors.
Georgia Hatzivassiliou, Bonnie Liu, Carol O'Brien, Jill M Spoerke, Klaus P Hoeflich, Garret M Hampton

Mol Cancer Ther· May 2012

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DNA methylation profiling defines clinically relevant biological subsets of non-small cell lung cancer.
Kim Walter, Thomas Holcomb, Tom Januario, Pan Du, Marie Evangelista, Garret M Hampton

Clin Cancer Res· April 2012

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Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib.
Elizabeth A Punnoose, Siminder Atwal, Weiqun Liu, Rajiv Raja, Bernard M Fine, Garret M Hampton

Clin Cancer Res· April 2012

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Profiling bladder cancer organ site-specific metastasis identifies LAMC2 as a novel biomarker of hematogenous dissemination.
Steven Christopher Smith, Brian Nicholson, Matthew Nitz, Henry F Frierson, Mark Smolkin, Garret Hampton

Am J Pathol· February 2009

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Cdc6 and cyclin E2 are PTEN-regulated genes associated with human prostate cancer metastasis.
Zhong Wu, HyungJun Cho, Garret M Hampton, Dan Theodorescu

Neoplasia· January 2009

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Aromatase inhibitors--gene discovery.
William R Miller, Alexey Larionov, Lorna Renshaw, Thomas J Anderson, Sharon White, Garret Hampton

J Steroid Biochem Mol Biol· November 2007

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Changes in breast cancer transcriptional profiles after treatment with the aromatase inhibitor, letrozole.
William R Miller, Alexey A Larionov, Lorna Renshaw, Thomas J Anderson, Sharon White, Garret Hampton

Pharmacogenet Genomics· October 2007

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