Publications by authors named "Gary H Posner"

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Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition.
Sujayita Roy, Arun Kapoor, Fei Zhu, Rupkatha Mukhopadhyay, Ayan Kumar Ghosh, Gary H Posner

J Biol Chem· October 2020

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Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs.
Jennifer M Fox, James R Moynihan, Bryan T Mott, Jennifer R Mazzone, Nicole M Anders, Gary H Posner

Oncotarget· February 2016

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Inhibition of human cytomegalovirus replication by artemisinins: effects mediated through cell cycle modulation.
Sujayita Roy, Ran He, Arun Kapoor, Michael Forman, Jennifer R Mazzone, Gary H Posner

Antimicrob Agents Chemother· July 2015

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Antimalarial chemotherapy: orally curative artemisinin-derived trioxane dimer esters.
Ryan C Conyers, Jennifer R Mazzone, Abhai K Tripathi, David J Sullivan, Gary H Posner

Bioorg Med Chem Lett· January 2015

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In vitro combination of anti-cytomegalovirus compounds acting through different targets: role of the slope parameter and insights into mechanisms of Action.
Hongyi Cai, Arun Kapoor, Ran He, Rajkumar Venkatadri, Michael Forman, Gary H Posner

Antimicrob Agents Chemother· September 2014

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A thiazole derivative of artemisinin moderately reduces Toxoplasma gondii cyst burden in infected mice.
Tracey L Schultz, Christopher P Hencken, Lauren E Woodard, Gary H Posner, Robert H Yolken

J Parasitol· August 2014

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Antimalarial chemotherapy: artemisinin-derived dimer carbonates and thiocarbonates.
Jennifer R Mazzone, Ryan C Conyers, Abhai K Tripathi, David J Sullivan, Gary H Posner

Bioorg Med Chem Lett· June 2014

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Age- and sex-dependent hormonal modulation of the expression of vitamin D receptor and 25-hydroxyvitamin D 1α hydroxylase in human bone cells.
Dalia Somjen, Sara Katzburg, David Hendel, Orli Sharon, Gary H Posner

Expert Rev Endocrinol Metab· May 2014

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The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether.
Ryan C Conyers, Jennifer R Mazzone, Maxime A Siegler, Abhai K Tripathi, David J Sullivan, Gary H Posner

Bioorg Med Chem Lett· March 2014

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Unique and highly selective anticytomegalovirus activities of artemisinin-derived dimer diphenyl phosphate stem from combination of dimer unit and a diphenyl phosphate moiety.
Ran He, Michael Forman, Bryan T Mott, Rajkumar Venkatadri, Gary H Posner

Antimicrob Agents Chemother· September 2013

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Artemisinin-derived dimer phosphate esters as potent anti-cytomegalovirus (anti-CMV) and anti-cancer agents: a structure-activity study.
Bryan T Mott, Ran He, Xiaochun Chen, Jennifer M Fox, Curt I Civin, Gary H Posner

Bioorg Med Chem· July 2013

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Synthesis and antimalarial efficacy of two-carbon-linked, artemisinin-derived trioxane dimers in combination with known antimalarial drugs.
Bryan T Mott, Abhai Tripathi, Maxime A Siegler, Cathy D Moore, David J Sullivan, Gary H Posner

J Med Chem· March 2013

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Differential photoprotective effects of 1,25-dihydroxyvitamin D3 and a low calcaemic deltanoid.
Katie M Dixon, Vanessa B Sequeira, Shivashni S Deo, Ritu Mohan, Gary H Posner

Photochem Photobiol Sci· December 2012

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A furoxan-amodiaquine hybrid as a potential therapeutic for three parasitic diseases().
Bryan T Mott, Ken Chih-Chien Cheng, Rajarshi Guha, Valerie P Kommer, David L Williams, Gary H Posner

Medchemcomm· December 2012

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Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose.
Alexander M Jacobine, Jennifer R Mazzone, Rachel D Slack, Abhai K Tripathi, David J Sullivan, Gary H Posner

J Med Chem· September 2012

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Artemisinin-derived dimer diphenyl phosphate is an irreversible inhibitor of human cytomegalovirus replication.
Ran He, Kyoungsook Park, Hongyi Cai, Arun Kapoor, Michael Forman, Gary H Posner

Antimicrob Agents Chemother· July 2012

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An artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activities.
Ran He, Bryan T Mott, Andrew S Rosenthal, Douglas T Genna, Gary H Posner

PLoS One· April 2012

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Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine.
Rachel D Slack, Bryan T Mott, Lauren E Woodard, Abhai Tripathi, David Sullivan, Gary H Posner

J Med Chem· January 2012

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Three-component, one-flask synthesis of rhodanines (thiazolidinones).
Alexander M Jacobine, Gary H Posner

J Org Chem· October 2011

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Cyanocuprates convert carboxylic acids directly into ketones.
Douglas T Genna, Gary H Posner

Org Lett· October 2011

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Highly stereocontrolled and regiocontrolled syntheses of 2,3,4-trisubstituted alkanoates and lactones.
Christopher P Hencken, Douglas T Genna, Maxime A Siegler, Gary H Posner

J Org Chem· June 2011

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A single, low, oral dose of a 5-carbon-linked trioxane dimer orthoester plus mefloquine cures malaria-infected mice.
Deuk Kyu Moon, Abhai Tripathi, David Sullivan, Maxime A Siegler, Sean Parkin, Gary H Posner

Bioorg Med Chem Lett· May 2011

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Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors.
Ran He, Gordon Sandford, Gary S Hayward, William H Burns, Gary H Posner

Virol J· January 2011

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α-Chloro-β,γ-ethylenic esters: enantiocontrolled synthesis and substitutions.
Douglas T Genna, Christopher P Hencken, Maxime A Siegler, Gary H Posner

Org Lett· October 2010

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Apc(MIN) modulation of vitamin D secosteroid growth control.
Haibo Xu, Gary H Posner, Michael Stevenson, Frederick C Campbell

Carcinogenesis· August 2010

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