Publications by authors named "Gary Landreth"

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Basic Science and Pathogenesis.
Israel Coronel, Henika Patel, Abigail Wallace, Disha Soni, Pablo Martinez, Gary E Landreth

Alzheimers Dement· December 2025

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Basic Science and Pathogenesis.
Evan J Messenger, Sydney Baar, Logan M Bedford, Andy P Tsai, Peter Bor-Chian Lin, Gary E Landreth

Alzheimers Dement· December 2025

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Neuroinflammation in Alzheimer disease.
Michael T Heneka, Wiesje M van der Flier, Frank Jessen, Jeroen Hoozemanns, Dietmar Rudolf Thal, Gary Landreth

Nat Rev Immunol· May 2025

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PLCG2 modulates TREM2 expression and signaling in response to Alzheimer's disease pathology.
Evan J Messenger, Sydney A Baar, Logan M Bedford, Andy P Tsai, Peter Bor-Chian Lin, Gary E Landreth

Alzheimers Dement· May 2025

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Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer's progression.
Juan F Codocedo, Claudia Mera-Reina, Peter Bor-Chian Lin, Paul B Fallen, Shweta S Puntambekar, Gary E Landreth

Cell Rep· July 2024

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Functional 3'-UTR Variants Identify Regulatory Mechanisms Impacting Alcohol Use Disorder and Related Traits.
Andy B Chen, Xuhong Yu, Kriti S Thapa, Hongyu Gao, Jill L Reiter, Gary E Landreth

bioRxiv· February 2024

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Deep learning-driven adaptive optics for single-molecule localization microscopy.
Peiyi Zhang, Donghan Ma, Xi Cheng, Andy P Tsai, Yu Tang, Gary E Landreth

Nat Methods· November 2023

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Therapeutic targeting of immunometabolism in Alzheimer's disease reveals a critical reliance on Hexokinase 2 dosage on microglial activation and disease progression.
Juan F Codocedo, Claudia Mera-Reina, Peter Bor-Chian Lin, Shweta S Puntambekar, Brad T Casali, Gary E Landreth

bioRxiv· November 2023

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Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease.
Andy P Tsai, Chuanpeng Dong, Peter Bor-Chian Lin, Adrian L Oblak, Gonzalo Viana Di Prisco, Gary E Landreth

Immunity· September 2023

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INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease.
Peter Bor-Chian Lin, Andy Po-Yi Tsai, Disha Soni, Audrey Lee-Gosselin, Miguel Moutinho, Gary E Landreth

Alzheimers Dement· June 2023

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Integrating multimodality magnetic resonance imaging to the Allen Mouse Brain Common Coordinate Framework.
Nian Wang, Surendra Maharjan, Andy P Tsai, Peter B Lin, Yi Qi, Gary E Landreth

NMR Biomed· May 2023

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Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis.
Season K Wyatt-Johnson, Holly N Kersey, Juan F Codocedo, Kathy L Newell, Gary E Landreth

J Neuroinflammation· March 2023

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TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation.
Miguel Moutinho, Israel Coronel, Andy P Tsai, Gonzalo Viana Di Prisco, Taylor Pennington, Gary E Landreth

Genome Med· February 2023

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Bassoon contributes to tau-seed propagation and neurotoxicity.
Pablo Martinez, Henika Patel, Yanwen You, Nur Jury, Abigail Perkins, Gary E Landreth

Nat Neurosci· December 2022

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The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model.
Christel Claes, Whitney E England, Emma P Danhash, Sepideh Kiani Shabestari, Amit Jairaman, Gary E Landreth

Alzheimers Dement· October 2022

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Corrigendum: Age-dependent microstructure alterations in 5xFAD mice by high-resolution diffusion tensor imaging.
Surendra Maharjan, Andy P Tsai, Peter B Lin, Cynthia Ingraham, Megan R Jewett, Gary E Landreth

Front Neurosci· October 2022

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The intersection of metabolism and inflammation is governed by the intracellular topology of hexokinases and the metabolic fate of glucose.
Juan F Codocedo, Gary E Landreth

Immunometabolism (Cobham)· October 2022

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Age-dependent microstructure alterations in 5xFAD mice by high-resolution diffusion tensor imaging.
Surendra Maharjan, Andy P Tsai, Peter B Lin, Cynthia Ingraham, Megan R Jewett, Gary E Landreth

Front Neurosci· August 2022

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CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease.
Shweta S Puntambekar, Miguel Moutinho, Peter Bor-Chian Lin, Vaishnavi Jadhav, Danika Tumbleson-Brink, Gary E Landreth

Mol Neurodegener· June 2022

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The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.
Miguel Moutinho, Shweta S Puntambekar, Andy P Tsai, Israel Coronel, Peter B Lin, Gary E Landreth

Sci Transl Med· March 2022

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PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer's disease.
Andy P Tsai, Chuanpeng Dong, Peter Bor-Chian Lin, Evan J Messenger, Brad T Casali, Gary E Landreth

Genome Med· February 2022

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TREM2 splicing emerges as crucial aspect to understand TREM2 biology.
Miguel Moutinho, Gary E Landreth

J Leukoc Biol· November 2021

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INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia.
Andy P Tsai, Peter Bor-Chian Lin, Chuanpeng Dong, Miguel Moutinho, Brad T Casali, Gary E Landreth

Neurobiol Dis· June 2021

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CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10.
Ian H Guldner, Qingfei Wang, Lin Yang, Samantha M Golomb, Zhuo Zhao, Gary E Landreth

Cell· November 2020

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Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice.
Vaishnavi S Jadhav, Peter B C Lin, Taylor Pennington, Gonzalo Viana Di Prisco, Asha Jacob Jannu, Gary E Landreth

Mol Neurodegener· October 2020

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