Publications by authors named "Gary Silkstone"

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Taming hemoglobin chemistry-a new hemoglobin-based oxygen carrier engineered with both decreased rates of nitric oxide scavenging and lipid oxidation.
Chris E Cooper, Michelle Simons, Alex Dyson, Nélida Leiva Eriksson, Gary G A Silkstone

Exp Mol Med· October 2024

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Stability of Maleimide-PEG and Mono-Sulfone-PEG Conjugation to a Novel Engineered Cysteine in the Human Hemoglobin Alpha Subunit.
Chris E Cooper, Matthew Bird, XiaoBo Sheng, Ji-Won Choi, Gary G A Silkstone

Front Chem· July 2021

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Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality.
Chris E Cooper, Gary G A Silkstone, Michelle Simons, Svetlana Gretton, Badri S Rajagopal

Biomater Sci· July 2020

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Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute.
Chris E Cooper, Gary G A Silkstone, Michelle Simons, Badri Rajagopal, Natalie Syrett

Free Radic Biol Med· April 2019

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Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers.
Michelle Simons, Svetlana Gretton, Gary G A Silkstone, Badri S Rajagopal, Victoria Allen-Baume

Biosci Rep· August 2018

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Engineering tyrosine electron transfer pathways decreases oxidative toxicity in hemoglobin: implications for blood substitute design.
Gary G A Silkstone, Rebecca S Silkstone, Michael T Wilson, Michelle Simons, Leif Bülow

Biochem J· October 2016

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A Further Investigation of the Effects of Extremely Low Frequency Magnetic Fields on Alkaline Phosphatase and Acetylcholinesterase.
Gary Silkstone, Michael T Wilson

PLoS One· July 2016

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Kinetic studies on the oxidation of semiquinone and hydroquinone forms of Arabidopsis cryptochrome by molecular oxygen.
Luuk J G W van Wilderen, Gary Silkstone, Maria Mason, Jasper J van Thor, Michael T Wilson

FEBS Open Bio· December 2015

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NO binding to the proapoptotic cytochrome c-cardiolipin complex.
Michael A Hough, Gary Silkstone, J A R Worrall, Michael T Wilson

Vitam Horm· April 2015

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The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant.
Badri S Rajagopal, Ann N Edzuma, Michael A Hough, Katie L I M Blundell, Valerian E Kagan, Gary G Silkstone

Biochem J· December 2013

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Haptoglobin binding stabilizes hemoglobin ferryl iron and the globin radical on tyrosine β145.
Chris E Cooper, Dominik J Schaer, Paul W Buehler, Michael T Wilson, Brandon J Reeder, Gary Silkstone

Antioxid Redox Signal· June 2013

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An investigation into a cardiolipin acyl chain insertion site in cytochrome c.
Badri S Rajagopal, Gary G Silkstone, Peter Nicholls, Michael T Wilson, Jonathan A R Worrall

Biochim Biophys Acta· May 2012

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Reexamination of magnetic isotope and field effects on adenosine triphosphate production by creatine kinase.
Darragh Crotty, Gary Silkstone, Soumya Poddar, Richard Ranson, Adriele Prina-Mello

Proc Natl Acad Sci U S A· January 2012

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Probing a complex of cytochrome c and cardiolipin by magnetic circular dichroism spectroscopy: implications for the initial events in apoptosis.
Justin M Bradley, Gary Silkstone, Michael T Wilson, Myles R Cheesman, Julea N Butt

J Am Chem Soc· December 2011

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Nitric oxide binds to the proximal heme coordination site of the ferrocytochrome c/cardiolipin complex: formation mechanism and dynamics.
Gary Silkstone, Sofia M Kapetanaki, Ivan Husu, Marten H Vos, Michael T Wilson

J Biol Chem· June 2010

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Interaction of carbon monoxide with the apoptosis-inducing cytochrome c-cardiolipin complex.
Sofia M Kapetanaki, Gary Silkstone, Ivan Husu, Ursula Liebl, Michael T Wilson

Biochemistry· February 2009

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Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells.
Luiz C Godoy, Cristina Muñoz-Pinedo, Laura Castro, Simone Cardaci, Christopher M Schonhoff, Gary G Silkstone

Proc Natl Acad Sci U S A· February 2009

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Ligand dynamics in an electron transfer protein. Picosecond geminate recombination of carbon monoxide to heme in mutant forms of cytochrome c.
Gary Silkstone, Audrius Jasaitis, Michael T Wilson, Marten H Vos

J Biol Chem· January 2007

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EPR and optical spectroscopic studies of Met80X mutants of yeast ferricytochrome c. Models for intermediates in the alkaline transition.
Gary G Silkstone, Christopher E Cooper, Dimitri Svistunenko, Michael T Wilson

J Am Chem Soc· January 2005

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Production and characterisation of Met80X mutants of yeast iso-1-cytochrome c: spectral, photochemical and binding studies on the ferrous derivatives.
Gary Silkstone, Glyn Stanway, Peter Brzezinski, Michael T Wilson

Biophys Chem· July 2002

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