Publications by authors named "Gaurav Swarnkar"

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inhibits the NLRP3 inflammasome in macrophages during the early phases of intracellular infection, but not the late phases.
Saumya Bhagat, Khushpreet Kaur, Luke O'Connor, Chun Wang, Yongjia Li, Gaurav Swarnkar

bioRxiv· September 2025

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IĸBζ as a Central Modulator of Inflammatory Arthritis Pathogenesis.
Gaurav Swarnkar, Musarrat Naaz, Dorothy Mims, Prashant Gupta, Timothy Peterson

Arthritis Rheumatol· February 2025

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DNA hypomethylation ameliorates erosive inflammatory arthritis by modulating interferon regulatory factor-8.
Gaurav Swarnkar, Nicholas P Semenkovich, Manoj Arra, Dorothy K Mims, Syeda Kanwal Naqvi

Proc Natl Acad Sci U S A· February 2024

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STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice.
Susan MacLauchlan, Priyanka Kushwaha, Albert Tai, Sijia Chen, Catherine Manning, Gaurav Swarnkar

Proc Natl Acad Sci U S A· April 2023

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Glutamine metabolism modulates chondrocyte inflammatory response.
Manoj Arra, Gaurav Swarnkar, Naga Suresh Adapala, Syeda Kanwal Naqvi, Lei Cai

Elife· August 2022

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IκB-ζ signaling promotes chondrocyte inflammatory phenotype, senescence, and erosive joint pathology.
Manoj Arra, Gaurav Swarnkar, Yael Alippe, Gabriel Mbalaviele, Yousef Abu-Amer

Bone Res· February 2022

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Methods to Analyze the Roles of TAK1, TRAF6, and NEMO in the Regulation of NF-κB Signaling by RANK Stimulation During Osteoclastogenesis.
Gaurav Swarnkar, Manoj Arra, Suresh Adapala, Yousef Abu-Amer

Methods Mol Biol· January 2022

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Gasdermin D deficiency attenuates arthritis induced by traumatic injury but not autoantibody-assembled immune complexes.
Tong Yang, Kai Sun, Chun Wang, Gaurav Swarnkar, Songtao Quan

Arthritis Res Ther· November 2021

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Targeting angiogenesis for fracture nonunion treatment in inflammatory disease.
Cuicui Wang, Jun Ying, Xiaolei Nie, Tianhong Zhou, Ding Xiao, Gaurav Swarnkar

Bone Res· June 2021

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LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis.
Manoj Arra, Gaurav Swarnkar, Ke Ke, Jesse E Otero, Jun Ying

Nat Commun· July 2020

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Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO.
Naga Suresh Adapala, Gaurav Swarnkar, Manoj Arra, Jie Shen, Gabriel Mbalaviele

Elife· March 2020

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Attenuation of NF-κB in Intestinal Epithelial Cells Is Sufficient to Mitigate the Bone Loss Comorbidity of Experimental Mouse Colitis.
Ke Ke, Tim Hung-Po Chen, Manoj Arra, Gabriel Mbalaviele, Gaurav Swarnkar

J Bone Miner Res· October 2019

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Inflammatory Responses Reprogram T Through Impairment of Neuropilin-1.
Tim Hung-Po Chen, Manoj Arra, Gabriel Mbalaviele, Gaurav Swarnkar, Yousef Abu-Amer

Sci Rep· July 2019

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Targeting vascular endothelial growth factor ameliorates PMMA-particles induced inflammatory osteolysis in murine calvaria.
Wahid Abu-Amer, Manoj Arra, John C F Clohisy, Yousef Abu-Amer, Gaurav Swarnkar

Bone· June 2019

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Corrigendum to "A novel flavonoid isolated from the steam-bark of Ulmus wallichiana planchon stimulates osteoblast function and inhibits osteoclast and adipocyte differentiation" [Eur. J. Pharmacol. 658(2-3) 2011 65-73].
Gaurav Swarnkar, Kunal Sharan, Jawed Siddiqui, Bandana Chakravarti, Preeti Rawat

Eur J Pharmacol· July 2018

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NUMBL Interacts with TAK1, TRAF6 and NEMO to Negatively Regulate NF-κB Signaling During Osteoclastogenesis.
Gaurav Swarnkar, Tim Hung-Po Chen, Manoj Arra, Amjad M Nasir, Gabriel Mbalaviele

Sci Rep· October 2017

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Myeloid Deletion of Nemo Causes Osteopetrosis in Mice Owing to Upregulation of Transcriptional Repressors.
Gaurav Swarnkar, Kyuhwan Shim, Amjad M Nasir, Kuljeet Seehra, Hung-Po Tim Chen

Sci Rep· July 2016

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Regulation of NF-κB signaling in osteoclasts and myeloid progenitors.
Gaurav Swarnkar, Yousef Abu-Amer

Methods Mol Biol· November 2015

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Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development.
Gaurav Swarnkar, Kaihua Zhang, Gabriel Mbalaviele, Fanxin Long, Yousef Abu-Amer

PLoS One· May 2015

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Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling.
Gaurav Swarnkar, Kannan Karuppaiah, Gabriel Mbalaviele, Tim Hung-Po Chen, Yousef Abu-Amer

Proc Natl Acad Sci U S A· January 2015

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Co-expression of Arabidopsis transcription factor, AtMYB12, and soybean isoflavone synthase, GmIFS1, genes in tobacco leads to enhanced biosynthesis of isoflavones and flavonols resulting in osteoprotective activity.
Ashutosh Pandey, Prashant Misra, Mohd P Khan, Gaurav Swarnkar, Mahesh C Tewari

Plant Biotechnol J· January 2014

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RhoA-mediated signaling in mechanotransduction of osteoblasts.
Kazunori Hamamura, Gaurav Swarnkar, Nancy Tanjung, Eunhye Cho, Jiliang Li

Connect Tissue Res· June 2013

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Identification of novel 2-((1-(benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)benzoic acid analogues as BMP-2 stimulators.
Vishal M Balaramnavar, Imran A Khan, Jawed Akhtar Siddiqui, Mohd Parvez Khan, Bandana Chakravarti, Gaurav Swarnkar

J Med Chem· October 2012

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EGb 761 promotes osteoblastogenesis, lowers bone marrow adipogenesis and atherosclerotic plaque formation.
Jyoti Gautam, Priyanka Kushwaha, Gaurav Swarnkar, Vikram Khedgikar, Geet K Nagar

Phytomedicine· September 2012

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A naturally occurring naringenin derivative exerts potent bone anabolic effects by mimicking oestrogen action on osteoblasts.
Gaurav Swarnkar, Kunal Sharan, Jawed A Siddiqui, Jay Sharan Mishra, Kainat Khan

Br J Pharmacol· March 2012

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