Publications by authors named "Ge Chenxu"

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Metabolic insults-initialised nonalcoholic steatohepatitis promoted by fine particulate matter challenge: A mechanism involving RNF15-driven ASK1 degradation.
Minghui Chang, Junjie Zhao, Haonan Fan, Zongxin Shi, Minxuan Xu, Chenxu Ge

Free Radic Biol Med· November 2025

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Targeting PYK2 with heterobifunctional T6BP helps mitigate MASLD and MASH-HCC progression.
Minxuan Xu, Junjie Zhao, Liancai Zhu, Chenxu Ge, Yan Sun

J Hepatol· February 2025

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Radish red attenuates chronic kidney disease in obese mice through repressing oxidative stress and ferroptosis via Nrf2 signaling improvement.
Qiang Li, Yanbin Zheng, Jianyu Zhao, Xinyi Wei, Zongxin Shi, Chenxu Ge

Int Immunopharmacol· December 2024

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Exploring shared molecular signatures and regulatory mechanisms in nonalcoholic steatohepatitis and inflammatory bowel disease using integrative bioinformatics analysis.
Zixuan Zhong, Minxuan Xu, Chenxu Ge, Jun Tan

Sci Rep· May 2024

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Corrigendum to "Cynapanoside A exerts protective effects against obesity-induced diabetic nephropathy through ameliorating TRIM31-mediated inflammation, lipid synthesis and fibrosis" [Int. Immunopharmacol. 113 (Part B) (2022) 109395].
Jing Luo, Jun Tan, Junjie Zhao, Longyan Wang, Jin Liu, Chenxu Ge

Int Immunopharmacol· December 2023

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Corrigendum to "Mulberrin confers protection against hepatic fibrosis by Trim31/Nrf2 signaling" [Redox Biol. 51 (2022) 102274].
Chenxu Ge, Jun Tan, Deshuai Lou, Liancai Zhu, Zixuan Zhong

Redox Biol· December 2023

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Palmitoyltransferase ZDHHC3 Aggravates Nonalcoholic Steatohepatitis by Targeting S-Palmitoylated IRHOM2.
Minxuan Xu, Jun Tan, Liancai Zhu, Chenxu Ge, Yi Zhang

Adv Sci (Weinh)· December 2023

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Palmitoyltransferase ZDHHC3 Aggravates Nonalcoholic Steatohepatitis by Targeting S-Palmitoylated IRHOM2.
Minxuan Xu, Jun Tan, Liancai Zhu, Chenxu Ge, Yi Zhang

Adv Sci (Weinh)· October 2023

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Tripartite motif containing 26 prevents steatohepatitis progression by suppressing C/EBPδ signalling activation.
Minxuan Xu, Jun Tan, Xin Liu, Li Han, Chenxu Ge

Nat Commun· October 2023

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The deubiquitinating enzyme 13 retards non-alcoholic steatohepatitis blocking inactive rhomboid protein 2-dependent pathway.
Minxuan Xu, Jun Tan, Liancai Zhu, Chenxu Ge, Wei Dong

Acta Pharm Sin B· March 2023

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Tripartite motif-containing protein 31 confers protection against nonalcoholic steatohepatitis by deactivating mitogen-activated protein kinase kinase kinase 7.
Min-Xuan Xu, Jun Tan, Chen-Xu Ge, Wei Dong, Li-Ting Zhang

Hepatology· January 2023

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Cynapanoside A exerts protective effects against obesity-induced diabetic nephropathy through ameliorating TRIM31-mediated inflammation, lipid synthesis and fibrosis.
Jing Luo, Jun Tan, Junjie Zhao, Longyan Wang, Jin Liu, Chenxu Ge

Int Immunopharmacol· December 2022

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Hepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK.
Chenxu Ge, Jun Tan, Xianling Dai, Qin Kuang, Shaoyu Zhong

Nat Commun· October 2022

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Mulberrin confers protection against hepatic fibrosis by Trim31/Nrf2 signaling.
Chenxu Ge, Jun Tan, Deshuai Lou, Liancai Zhu, Zixuan Zhong

Redox Biol· May 2022

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The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes.
Minxuan Xu, Jun Tan, Wei Dong, Benkui Zou, Xuepeng Teng, Chenxu Ge

Nat Commun· February 2022

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Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction.
Ling Li, Bo Fang, Yinglei Zhang, Liuqing Yan, Yuxin He, Chenxu Ge

Biomed Pharmacother· January 2022

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Juglanin protects against high fat diet-induced renal injury by suppressing inflammation and dyslipidemia via regulating NF-κB/HDAC3 signaling.
Qiang Li, Chenxu Ge, Jun Tan, Yan Sun, Qin Kuang

Int Immunopharmacol· June 2021

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iRhom2 Promotes Hepatic Steatosis by Activating MAP3K7-Dependent Pathway.
Minxuan Xu, Chenxu Ge, Liancai Zhu, Yuting Qin, Chengjiang Du

Hepatology· April 2021

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Carminic acid supplementation protects against fructose-induced kidney injury mainly through suppressing inflammation and oxidative stress via improving Nrf-2 signaling.
Qiang Li, Qifei Xu, Jun Tan, Linfeng Hu, Chenxu Ge

Aging (Albany NY)· April 2021

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Fisetin protects against high fat diet-induced nephropathy by inhibiting inflammation and oxidative stress via the blockage of iRhom2/NF-κB signaling.
Ge Chenxu, Dai Xianling, Kuang Qin, Hu Linfeng, Sun Yan

Int Immunopharmacol· March 2021

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Dysfunctional Rhbdf2 of proopiomelanocortin mitigates ambient particulate matter exposure-induced neurological injury and neuron loss by antagonizing oxidative stress and inflammatory reaction.
Min-Xuan Xu, Xian-Ling Dai, Qin Kuang, Lian-Cai Zhu, Lin-Feng Hu

J Hazard Mater· December 2020

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Nrf2 mitigates prolonged PM2.5 exposure-triggered liver inflammation by positively regulating SIKE activity: Protection by Juglanin.
Chenxu Ge, Jun Tan, Shaoyu Zhong, Lili Lai, Geng Chen

Redox Biol· September 2020

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Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses.
Lu Liu, Shuaiyi Chen, Miao Yu, Chenxu Ge, Mengmeng Ren

Cell Death Dis· July 2020

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Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation.
Minxuan Xu, Chenxu Ge, Yuting Qin, Deshuai Lou, Qiang Li

Mol Metab· April 2020

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Nrf2 deficiency aggravates PM-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorder.
Chenxu Ge, Linfeng Hu, Deshuai Lou, Qiang Li, Jing Feng

Aging (Albany NY)· March 2020

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