Publications by authors named "Geert Geeven"

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Nanopore long-read sequencing for the critically ill facilitates ultrarapid diagnostics and urgent clinical decision making.
Daphne J Smits, Federico Ferraro, Mark Drost, Herma C van der Linde, Bianca M de Graaf, Geert Geeven

Eur J Hum Genet· October 2025

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Re-analysis of whole genome sequencing ends a diagnostic odyssey: Case report of an RNU4-2 related neurodevelopmental disorder.
Rachel Schot, Federico Ferraro, Geert Geeven, Karin E M Diderich, Tahsin Stefan Barakat

Clin Genet· October 2024

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The role of confined placental mosaicism in fetal growth restriction: A retrospective cohort study.
Geerke M Eggenhuizen, Attie T J I Go, Zoë Sauter, Mariëtte J V Hoffer, Monique C Haak, Geert Geeven

Prenat Diagn· March 2024

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Evaluation of Circulating Tumor DNA as a Liquid Biomarker in Uveal Melanoma.
Daniel P de Bruyn, Natasha M van Poppelen, Tom Brands, Susanne C van den Boom, Ellis Eikenboom, Geert Geeven

Invest Ophthalmol Vis Sci· February 2024

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Early detection of active Human CytomegaloVirus (hCMV) infection in pregnant women using data generated for noninvasive fetal aneuploidy testing.
Brigitte H W Faas, Galuh Astuti, Willem J G Melchers, Annette Reuss, Christian Gilissen, Geert Geeven

EBioMedicine· February 2024

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AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model.
Ruizhi Deng, Eva Medico-Salsench, Anita Nikoncuk, Reshmi Ramakrishnan, Kristina Lanko, Geert Geeven

Acta Neuropathol· August 2023

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Pyruvate metabolism controls chromatin remodeling during CD4 T cell activation.
Enric Mocholi, Laura Russo, Keshav Gopal, Andrew G Ramstead, Sophia M Hochrein, Geert Geeven

Cell Rep· June 2023

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Web-accessible application for identifying pathogenic transcripts with RNA-seq: Increased sensitivity in diagnosis of neurodevelopmental disorders.
Jordy Dekker, Rachel Schot, Michiel Bongaerts, Walter G de Valk, Monique M van Veghel-Plandsoen, Geert Geeven

Am J Hum Genet· February 2023

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Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation.
Amelia Weber Hall, Mark Chaffin, Carolina Roselli, Honghuang Lin, Steven A Lubitz, Geert Geeven

Circ Genom Precis Med· December 2020

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Recently Evolved Enhancers Emerge with High Interindividual Variability and Less Frequently Associate with Disease.
Bas Castelijns, Mirna L Baak, Geert Geeven, Marit W Vermunt, Caroline R M Wiggers

Cell Rep· June 2020

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Multi-contact 4C: long-molecule sequencing of complex proximity ligation products to uncover local cooperative and competitive chromatin topologies.
Carlo Vermeulen, Amin Allahyar, Britta A M Bouwman, Peter H L Krijger, Marjon J A M Verstegen, Geert Geeven

Nat Protoc· February 2020

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4C-seq from beginning to end: A detailed protocol for sample preparation and data analysis.
Peter H L Krijger, Geert Geeven, Valerio Bianchi, Catharina R E Hilvering, Wouter de Laat

Methods· January 2020

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Bayesian mixture regression analysis for regulation of Pluripotency in ES cells.
Mehran Aflakparast, Geert Geeven, Mathisca C M de Gunst

BMC Bioinformatics· January 2020

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Hominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patients.
Bas Castelijns, Mirna L Baak, Ilia S Timpanaro, Caroline R M Wiggers, Marit W Vermunt, Geert Geeven

Nat Commun· January 2020

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Chromatin Conformation Links Putative Enhancers in Intracranial Aneurysm-Associated Regions to Potential Candidate Genes.
Melanie D Laarman, Geert Geeven, Phil Barnett, , Gabriël J E Rinkel

J Am Heart Assoc· May 2019

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peakC: a flexible, non-parametric peak calling package for 4C and Capture-C data.
Geert Geeven, Hans Teunissen, Wouter de Laat, Elzo de Wit

Nucleic Acids Res· September 2018

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Enhancer hubs and loop collisions identified from single-allele topologies.
Amin Allahyar, Carlo Vermeulen, Britta A M Bouwman, Peter H L Krijger, Marjon J A M Verstegen, Geert Geeven

Nat Genet· August 2018

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Sensitive Monogenic Noninvasive Prenatal Diagnosis by Targeted Haplotyping.
Carlo Vermeulen, Geert Geeven, Elzo de Wit, Marjon J A M Verstegen, Rumo P M Jansen

Am J Hum Genet· September 2017

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Enhancers reside in a unique epigenetic environment during early zebrafish development.
Lucas J T Kaaij, Michal Mokry, Meng Zhou, Michael Musheev, Geert Geeven

Genome Biol· July 2016

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Epigenomic annotation of gene regulatory alterations during evolution of the primate brain.
Marit W Vermunt, Sander C Tan, Bas Castelijns, Geert Geeven, Peter Reinink

Nat Neurosci· March 2016

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Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments.
Patrick J Wijchers, Peter H L Krijger, Geert Geeven, Yun Zhu, Annette Denker

Mol Cell· February 2016

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Local compartment changes and regulatory landscape alterations in histone H1-depleted cells.
Geert Geeven, Yun Zhu, Byung Ju Kim, Boris A Bartholdy, Seung-Min Yang

Genome Biol· December 2015

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YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers.
Giorgio G Galli, Matteo Carrara, Wei-Chien Yuan, Christian Valdes-Quezada, Basanta Gurung, Geert Geeven

Mol Cell· October 2015

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Characterization and dynamics of pericentromere-associated domains in mice.
Patrick J Wijchers, Geert Geeven, Michael Eyres, Atze J Bergsma, Mark Janssen

Genome Res· July 2015

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Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA.
Nicolas Léveillé, Carlos A Melo, Koos Rooijers, Angel Díaz-Lagares, Sonia A Melo, Geert Geeven

Nat Commun· March 2015

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