Publications by authors named "Geert Schenk"

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Age-impaired remyelination is associated with dysregulated microglial transitions.
Sameera Zia, Marianela E Traetta, Charbel S Baaklini, Brady P Hammond, Rebecca K John, Geert Schenk

Nat Commun· November 2025

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A focus on the normal-appearing white and gray matter within the multiple sclerosis brain: a link to smoldering progression.
Gema Muñoz González, Bert A T Hart, Marianna Bugiani, Jason R Plemel, Geert J Schenk

Acta Neuropathol· August 2025

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Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy.
Niels R C Meijns, Max Blokker, Sander Idema, Bert A 't Hart, Mitko Veta, Geert J Schenk

PLoS One· May 2025

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Thalamic atrophy in multiple sclerosis is associated with tract disconnection and altered microglia.
Carla Rodriguez-Mogeda, Ismail Koubiyr, Stefanos E Prouskas, Margarita Georgallidou, Susanne M A van der Pol, Geert J Schenk

Acta Neuropathol· May 2025

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Micro-diffusely abnormal white matter: An early multiple sclerosis lesion phase with intensified myelin blistering.
Antonio Luchicchi, Gema Muñoz-Gonzalez, Saar T Halperin, Eva Strijbis, Laura H M van Dijk, Geert J Schenk

Ann Clin Transl Neurol· April 2024

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Inhibitory synaptic loss drives network changes in multiple sclerosis: An ex vivo to in silico translational study.
Marijn Huiskamp, Svenja Kiljan, Shanna Kulik, Maarteen E Witte, Laura E Jonkman, Geert J Schenk

Mult Scler· November 2022

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Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination.
Samira Ghorbani, Emily Jelinek, Rajiv Jain, Benjamin Buehner, Cenxiao Li, Geert J Schenk

Nat Commun· May 2022

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The Forgotten Brother: The Innate-like B1 Cell in Multiple Sclerosis.
Saar T Halperin, Bert A 't Hart, Antonio Luchicchi, Geert J Schenk

Biomedicines· March 2022

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Myelin Quantification in White Matter Pathology of Progressive Multiple Sclerosis Post-Mortem Brain Samples: A New Approach for Quantifying Remyelination.
Marije J D Huitema, Eva M M Strijbis, Antonio Luchicchi, John G J M Bol, Jason R Plemel, Geert J Schenk

Int J Mol Sci· November 2021

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Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory.
Valeria Ramaglia, Mohit Dubey, M Alfonso Malpede, Naomi Petersen, Sharon I de Vries, Geert J Schenk

Acta Neuropathol· October 2021

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Mechanistic underpinning of an inside-out concept for autoimmunity in multiple sclerosis.
Bert A 't Hart, Antonio Luchicchi, Geert J Schenk, Peter K Stys, Jeroen J G Geurts

Ann Clin Transl Neurol· August 2021

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Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration.
Lynn van Olst, Carla Rodriguez-Mogeda, Carmen Picon, Svenja Kiljan, Rachel E James, Geert J Schenk

Acta Neuropathol· June 2021

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Multiple sclerosis and drug discovery: A work of translation.
Bert A 't Hart, Antonio Luchicchi, Geert J Schenk, Joep Killestein, Jeroen J G Geurts

EBioMedicine· June 2021

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Axon-Myelin Unit Blistering as Early Event in MS Normal Appearing White Matter.
Antonio Luchicchi, Bert't Hart, Irene Frigerio, Anne-Marie van Dam, Laura Perna, Geert J Schenk

Ann Neurol· April 2021

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Cortical axonal loss is associated with both gray matter demyelination and white matter tract pathology in progressive multiple sclerosis: Evidence from a combined MRI-histopathology study.
Svenja Kiljan, Paolo Preziosa, Laura E Jonkman, Wilma Dj van de Berg, Jos Twisk, Geert J Schenk

Mult Scler· March 2021

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Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity.
Wulin Teo, Andrew V Caprariello, Megan L Morgan, Antonio Luchicchi, Geert J Schenk

Proc Natl Acad Sci U S A· February 2021

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Engine Failure in Axo-Myelinic Signaling: A Potential Key Player in the Pathogenesis of Multiple Sclerosis.
Talia Bergaglio, Antonio Luchicchi, Geert J Schenk

Front Cell Neurosci· February 2021

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Cysteine Proteases and Mitochondrial Instability: A Possible Vicious Cycle in MS Myelin?
Anthony Poerwoatmodjo, Geert J Schenk, Jeroen J G Geurts, Antonio Luchicchi

Front Cell Neurosci· December 2020

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Endoplasmic reticulum stress in the dorsal root ganglia regulates large-conductance potassium channels and contributes to pain in a model of multiple sclerosis.
Muhammad Saad Yousuf, Samira Samtleben, Shawn M Lamothe, Timothy N Friedman, Ana Catuneanu, Geert J Schenk

FASEB J· September 2020

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Axonal degeneration as substrate of fractional anisotropy abnormalities in multiple sclerosis cortex.
Paolo Preziosa, Svenja Kiljan, Martijn D Steenwijk, Alessandro Meani, Wilma D J van de Berg, Geert J Schenk

Brain· July 2019

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Enhanced GABAergic Immunoreactivity in Hippocampal Neurons and Astroglia of Multiple Sclerosis Patients.
Svenja Kiljan, Marloes Prins, Bart M Baselmans, John G J M Bol, Geert J Schenk

J Neuropathol Exp Neurol· June 2019

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Structural network topology relates to tissue properties in multiple sclerosis.
Svenja Kiljan, Kim A Meijer, Martijn D Steenwijk, Petra J W Pouwels, Menno M Schoonheim, Geert J Schenk

J Neurol· January 2019

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Oscillatory brain activity associates with neuroligin-3 expression and predicts progression free survival in patients with diffuse glioma.
Jolanda Derks, Pieter Wesseling, Ellen W S Carbo, Arjan Hillebrand, Edwin van Dellen, Geert J Schenk

J Neurooncol· November 2018

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Insights into the Mechanisms That May Clarify Obesity as a Risk Factor for Multiple Sclerosis.
Marije J D Huitema, Geert J Schenk

Curr Neurol Neurosci Rep· March 2018

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Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis.
Jason R Plemel, Andrew V Caprariello, Michael B Keough, Tyler J Henry, Shigeki Tsutsui, Geert J Schenk

J Cell Biol· April 2017

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