Publications by authors named "Geert van Loo"

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ATG9A-mediated autophagy prevents inflammatory skin disease by limiting TNFR1-driven STING activation and ZBP1-dependent cell death.
Dario Priem, Jon Huyghe, Barbara Gilbert, Simon Verdonck, Tom Delanghe, Geert van Loo

Immunity· December 2025

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Pyrin inflammasome-driven erosive arthritis caused by unprenylated RHO GTPase signaling.
Murali K Akula, Elisabeth Gilis, Pieter Hertens, Lieselotte Vande Walle, Mozes Sze, Geert van Loo

EMBO Mol Med· October 2025

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Correction: NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells.
Scott Layzell, Alessandro Barbarulo, Geert van Loo, Rudi Beyaert, Benedict Seddon

Cell Death Differ· May 2025

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Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway.
Monika Julia Wolf, Alexandra Hoos, Judith Bauer, Steffen Boettcher, Markus Knust, Geert van Loo

Cancer Cell· May 2025

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Author Correction: A20 controls intestinal homeostasis through cell-specific activities.
Lars Vereecke, Sara Vieira-Silva, Thomas Billiet, Johan H van Es, Conor Mc Guire, Geert van Loo

Nat Commun· March 2025

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NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells.
Scott Layzell, Alessandro Barbarulo, Geert van Loo, Rudi Beyaert, Benedict Seddon

Cell Death Differ· February 2025

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Interleukin-33-activated basophils promote asthma by regulating Th2 cell entry into lung tissue.
Martijn J Schuijs, Claudia M Brenis Gomez, Fabian Bick, Justine Van Moorleghem, Manon Vanheerswynghels, Geert van Loo

J Exp Med· December 2024

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Colibactin-driven colon cancer requires adhesin-mediated epithelial binding.
Maude Jans, Magdalena Kolata, Gillian Blancke, Aline D'Hondt, Claudia Gräf, Geert van Loo

Nature· November 2024

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Development of human innate immune responses in a humanized mouse model expressing four human myelopoiesis transgenes.
Hannah Stocks, Elisabeth De Leeuw, Bart N Lambrecht, Linos Vandekerckhove, Geert van Loo

Front Immunol· October 2024

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NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology.
Ine Paesmans, Kristof Van Kolen, Marc Vandermeeren, Pei-Yu Shih, Dirk Wuyts, Geert van Loo

Front Aging Neurosci· September 2024

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A20: a jack of all trades.
Pieter Hertens, Geert van Loo

Trends Cell Biol· May 2024

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Myeloid A20 is critical for alternative macrophage polarization and type-2 immune-mediated helminth resistance.
Ioanna Petta, Marie Thorp, Maarten Ciers, Gillian Blancke, Louis Boon, Geert van Loo

Front Immunol· April 2024

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Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease.
Sahana Srinivasan, Daliya Kancheva, Sofie De Ren, Takashi Saito, Maude Jans, Geert van Loo

Front Immunol· February 2024

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A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS.
Lisa Johann, Sasha Soldati, Kristin Müller, Josephine Lampe, Federico Marini, Geert van Loo

J Clin Invest· December 2023

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The autoinflammation-associated NLRC4 mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice.
Elien Eeckhout, Tomoko Asaoka, Hanne Van Gorp, Dieter Demon, Charlotte Girard-Guyonvarc'h, Geert van Loo

Front Immunol· December 2023

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Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation.
Lisette Van Hove, Annagiada Toniolo, Mohammad Ghiasloo, Kim Lecomte, Fleur Boone, Geert van Loo

Autophagy· November 2023

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Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion.
M Giulia Doglio, Lien Verboom, Emily Ruilova Sosoranga, Ulrika C Frising, Tomoko Asaoka, Geert van Loo

Sci Immunol· November 2023

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Sterile triggers drive joint inflammation in TNF- and IL-1β-dependent mouse arthritis models.
Alexandra Thiran, Ioanna Petta, Gillian Blancke, Marie Thorp, Guillaume Planckaert, Geert van Loo

EMBO Mol Med· October 2023

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Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice.
Karel F A Van Damme, Pieter Hertens, Arne Martens, Elisabeth Gilis, Dario Priem, Geert van Loo

Sci Rep· October 2023

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Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression.
Emily Van San, Angela C Debruyne, Geraldine Veeckmans, Yulia Y Tyurina, Vladimir A Tyurin, Geert van Loo

Cell Death Differ· September 2023

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OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection.
Lien Verboom, Christopher J Anderson, Maude Jans, Ioanna Petta, Gillian Blancke, Geert van Loo

Cell Death Dis· August 2023

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Colibactin-induced genotoxicity and colorectal cancer exacerbation critically depends on adhesin-mediated epithelial binding.
Maude Jans, Magdalena Kolata, Gillian Blancke, Maarten Ciers, Anders B Dohlman, Geert van Loo

bioRxiv· August 2023

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Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection.
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo

Cell Death Dis· April 2023

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ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway.
Jon Huyghe, Dario Priem, Lisette Van Hove, Barbara Gilbert, Jürgen Fritsch, Geert van Loo

Science· December 2022

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Glycyrrhizin-Based Hydrogels Accelerate Wound Healing of Normoglycemic and Diabetic Mouse Skin.
Maarten A Mees, Fleur Boone, Thomas Bouwen, Frederik Vanaerschot, Charlotte Titeca, Geert van Loo

Pharmaceutics· December 2022

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