Publications by authors named "Generosa Gomez"

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Diversity-Oriented Synthesis (DOS) Towards Calcitriol Analogs with Sulfur-Containing Side Chains.
Uxía Gómez-Bouzó, Generosa Gómez, Yagamare Fall

Int J Mol Sci· June 2025

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Design, synthesis and biological evaluation of a novel non-Gemini analog of UVB1 and crystal structure of its complex with the vitamin D receptor.
Uxía Gómez-Bouzó, Carole Peluso-Iltis, Hugo Santalla, Lieve Verlinden, Annemieke Verstuyf

Bioorg Chem· April 2025

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Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain.
Uxía Gómez-Bouzó, Carole Peluso-Iltis, Hugo Santalla, Mario Alfredo Quevedo, Lieve Verlinden

J Med Chem· June 2024

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Structural analysis and biological activities of C25-amino and C25-nitro vitamin D analogs.
Uxía Gómez-Bouzó, Anna Y Belorusova, Marcos L Rivadulla, Hugo Santalla, Lieve Verlinden

Bioorg Chem· July 2023

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On the mechanism of the dyotropic expansion of hydrindanes into decalins.
Hugo Santalla, Olalla Nieto Faza, Generosa Gómez, Yagamare Fall, Carlos Silva López

Org Biomol Chem· February 2022

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Synthesis, Characterization and Antimicrobial Activities of 1,4- Disubstituted 1,2,3-Triazole Compounds.
Seck Insa, Fall Alioune, Ba Lalla Aicha, Ndoye Samba Fama, Ka Seydou, Gomez Generosa

Curr Top Med Chem· June 2021

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Access to a Library of 1,3-disubstituted-1,2,3-triazenes and Evaluation of their Antimicrobial Properties.
Insa Seck, Samba F Ndoye, Lalla A Ba, Alioune Fall, Abdoulaye Diop, Generosa Gomez

Curr Top Med Chem· January 2021

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New Experimental and Computational Tools for Drug Discovery. Part - IX.
Generosa Gómez, Yagamare Fall, Humbert González-Díaz

Curr Top Med Chem· January 2021

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Easy Access to Polyfunctionalized Chiral Decalins.
Hugo Santalla, Zoila Gándara, Uxía Gómez-Bouzó, Generosa Gómez, Yagamare Fall

ACS Omega· October 2020

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Novel calcitriol analogue with an oxolane group: In vitro, in vivo, and in silico studies.
Diego J Obiol, Andrea Martínez, María J Ferronato, Mario A Quevedo, Silvina M Grioli

Arch Pharm (Weinheim)· May 2019

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Synthesis of a novel analog of calcitriol and its biological evaluation as antitumor agent.
María Julia Ferronato, Diego Javier Obiol, Eliana Noelia Alonso, Josefina Alejandra Guevara, Silvina Mariela Grioli

J Steroid Biochem Mol Biol· January 2019

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Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain.
Anna Y Belorusova, Andrea Martínez, Zoila Gándara, Generosa Gómez, Yagamare Fall

Eur J Med Chem· July 2017

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From Hydrindane to Decalin: A Mild Transformation through a Dyotropic Ring Expansion.
Hugo Santalla, Olalla Nieto Faza, Generosa Gómez, Yagamare Fall, Carlos Silva López

Org Lett· July 2017

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Use of surface plasmon resonance in the binding study of vitamin D, metabolites and analogues with vitamin D binding protein.
Pilar Canoa, Marcos L Rivadulla, Jonathan Popplewell, René van Oosten, Generosa Gómez

Anal Bioanal Chem· April 2017

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The UVB1 Vitamin D analogue inhibits colorectal carcinoma progression.
María Julia Ferronato, Eliana Noelia Alonso, Norberto Ariel Gandini, María Eugenia Fermento, María Emilia Villegas

J Steroid Biochem Mol Biol· October 2016

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New synthetic strategies to vitamin D analogues.
Isela García, Yagamare Fall, Generosa Gómez

Curr Top Med Chem· August 2015

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Vitamin D analogue: potent antiproliferative effects on cancer cell lines and lack of hypercalcemic activity.
María Julia Ferronato, Débora Gisele Salomón, María Eugenia Fermento, Norberto Ariel Gandini, Alejandro López Romero

Arch Pharm (Weinheim)· May 2015

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Review of synthesis, biological assay, and QSAR studies of HMGR inhibitors.
Isela García, Yagamare Fall, Generosa Gómez

Curr Top Med Chem· October 2012

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Synthesis and biological evaluation of a new vitamin D2 analogue.
Zoila Gándara, Manuel Pérez, Débora G Salomón, María J Ferronato, María E Fermento

Bioorg Med Chem Lett· October 2012

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Review of QSAR for DNA polymerase inhibitors and new models for heterogeneous series of compounds.
Isela García, Yagamare Fall, Generosa Gómez

Curr Comput Aided Drug Des· December 2011

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First computational chemistry multi-target model for anti-Alzheimer, anti-parasitic, anti-fungi, and anti-bacterial activity of GSK-3 inhibitors in vitro, in vivo, and in different cellular lines.
Isela García, Yagamare Fall, Generosa Gómez, Humberto González-Díaz

Mol Divers· May 2011

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QSAR, docking, and CoMFA studies of GSK3 inhibitors.
Isela García, Yagamare Fall, Generosa Gómez

Curr Pharm Des· March 2011

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An application of two MIFs-based tools (Volsurf+ and Pentacle) to binary QSAR: the case of a palinurin-related data set of non-ATP competitive glycogen synthase kinase 3β (GSK-3β) inhibitors.
Giuseppe Ermondi, Giulia Caron, Isela Garcia Pintos, Michela Gerbaldo, Manuel Pérez

Eur J Med Chem· March 2011

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Using topological indices to predict anti-Alzheimer and anti-parasitic GSK-3 inhibitors by multi-target QSAR in silico screening.
Isela García, Yagamare Fall, Generosa Gómez

Molecules· August 2010

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QSAR & complex network study of the HMGR inhibitors structural diversity.
Isela García, Yagamare Fall Diop, Generosa Gómez

Curr Drug Metab· May 2010

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