Publications by authors named "Geng-Lin Li"

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New CHARGE Syndrome Mouse Models Reveal the Contribution of the Enzymatic Activity of CHD7 in Pathogenesis.
Ze Wang, Shuhua Dong, Zhuxi Huang, Huiling Zhang, Shihang Mao, Geng-Lin Li

Genesis· December 2025

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Electroreceptors with a different kind of buzz.
Geng-Lin Li, Henrique von Gersdorff

J Physiol· November 2025

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In Vitro and Animal Studies of Human Natural Killer Cell-Derived Exosomes for the Treatment of Otitis Media.
Zirui Zhao, Liqin Wang, Zhen Guo, Kanglun Jiang, Jianghong Xu, Geng-Lin Li

Neurosci Bull· October 2025

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Comparative analysis of RNA versus protein splicing in dual AAV-mediated gene therapy in a mouse model of DFNB9 deafness.
Mengzhao Xun, Xintai Fan, Hui Wang, Jingjing Zhao, Gongrui Tang, Jianping Liu, Geng-Lin Li

Mol Ther· October 2025

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The X-Age Project to construct a Chinese aging clock.
Jiaming Li, Mengmeng Jiang, Qiaoran Wang, Zikai Zheng, Jianghua Shen, Jingyi Li, Yanling Fan, Lingling Geng, Lin Chen, Lingjing Jin, Geng-Lin Li, Ji Li, Jian Li, Mengfeng Li, Rong Li, Wei Li, Wei Li, Xiao-Jun Li, Xin Li, Qingfeng Liang, Zhen Liang, Haotian Lin, Baohua Liu, Cai-Yue Liu, Changsheng Liu, Feng Liu, Jianfeng Liu, Jun-Ping Liu, Ke Liu, Lin Liu, Pingsheng Liu, Qiang Liu, Qiang Liu, Tiemin Liu, Wenwen Liu, Xingguo Liu, Yajun Liu, Yong Liu, Youhua Liu, Youshuo Liu, Zhili Liu, Li Qiang, Liang Sun, Ling Tao, Xiao-Li Tian, Xiaolin Tong, Liheng Wang, Lin Wang, Songlin Wang, Lingyan Xu, Liying Yan, Liu Yang, Zhenglin Yang, Licheng Zhang, Lingqiang Zhang, Jialin C Zheng, Lili Zhou, Guang-Hui Liu

Nat Aging· September 2025

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Electrophysiological Characterization of Murine Vestibular Efferent Neurons and Modulation by Acute Peripheral Vestibular Deprivation.
Jinyu Wang, Mengfan Xu, Lei Zhang, Wenjie Liu, Siyue Wang, Liqin Wang, Geng-Lin Li

Neurosci Bull· September 2025

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Multifaceted Role of RIMBP2 in Promoting Hearing in Murine Cochlear Hair Cells.
Menghui Liao, Xin Chen, Ling Lu, Qing Liu, Rongrong Guo, Yige Li, Mingliang Tang, Huawei Li, Geng-Lin Li

Neurosci Bull· August 2025

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Combined AAV-mediated specific Gjb2 expression restores hearing in DFNB1 mouse models.
Qiuhan Sun, Fangzhi Tan, Liyan Zhang, Yicheng Lu, Hao Wei, Nianci Li, Ling Lu, Geng-Lin Li

Mol Ther· July 2025

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A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement.

Life Med· February 2025

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A base editor for the long-term restoration of auditory function in mice with recessive profound deafness.
Chong Cui, Shengyi Wang, Daqi Wang, Jingjing Zhao, Bowei Huang, Geng-Lin Li, Huawei Li

Nat Biomed Eng· January 2025

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The p. S178L mutation in Tbc1d24 disrupts endosome-mediated synaptic vesicle trafficking of cochlear hair cells and leads to hearing impairment in mice.
Penghui Chen, Shule Hou, Gen Li, Yuzhe Lin, Jiawen Lu, Geng-Lin Li

Clin Genet· January 2025

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Amitriptyline protects afferent synapses in the cochlea against excitotoxic trauma in vitro.
Liqin Wang, Mengfan Xu, Qing Zhang, Geng-Lin Li

FEBS J· September 2024

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Danshensu reduces neuronal excitability by enhancing potassium currents in bushy cells in the mouse cochlear nucleus.
Mengfan Xu, Liqin Wang, Geng-Lin Li, Zheng-Quan Tang

Neuroreport· July 2024

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Engineering of the AAV-Compatible Hair Cell-Specific Small-Size Myo15 Promoter for Gene Therapy in the Inner Ear.
Shao Wei Hu, Jun Lv, Zijing Wang, Honghai Tang, Hui Wang, Geng-Lin Li, Huawei Li

Research (Wash D C)· April 2024

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Hair cell-specific Myo15 promoter-mediated gene therapy rescues hearing in DFNB9 mouse model.
Hui Wang, MengZhao Xun, Honghai Tang, Jingjing Zhao, Shaowei Hu, Jianping Liu, Geng-Lin Li, Huawei Li

Mol Ther Nucleic Acids· March 2024

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P2X7 receptor is required for the ototoxicity caused by aminoglycoside in developing cochlear hair cells.
Cheng Cheng, Jiaoyao Ma, Xiaoling Lu, Panpan Zhang, Xiaohan Wang, Peifan Li, Geng-Lin Li, Huawei Li

Neurobiol Dis· July 2023

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Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Qianying Liu, Xiang Zhang, Hui Huang, Yuxin Chen, Fang Wang, Lin Han, Zhimin Liu, Geng-Lin Li

Nat Commun· May 2023

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Functional and developmental changes in the inner hair cell ribbon synapses caused by Myosin VI knockout and deafness-inducing point mutation.
Ning Yin, Jingjing Zhao, Panpan Zhang, Baofu Yu, Renjie Chai, Geng-Lin Li

Cell Death Discov· May 2023

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Estrogens rapidly shape synaptic and intrinsic properties to regulate the temporal precision of songbird auditory neurons.
Garrett B Scarpa, Joseph R Starrett, Geng-Lin Li, Colin Brooks, Yuichi Morohashi

Cereb Cortex· March 2023

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Generation of innervated cochlear organoid recapitulates early development of auditory unit.
Mingyu Xia, Jiaoyao Ma, Mingxuan Wu, Luo Guo, Yan Chen, Geng-Lin Li, Huawei Li, Wenyan Li

Stem Cell Reports· January 2023

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Comparative study of ionic currents and exocytosis in hair cells of the basilar and amphibian papilla in bullfrogs.
Jingjing Zhao, Ning Yin, Geng-Lin Li

Front Cell Neurosci· January 2023

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Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss.
Chong Cui, Daqi Wang, Bowei Huang, Fang Wang, Yuxin Chen, Dong Liu, Geng-Lin Li, Huawei Li

Mol Ther Nucleic Acids· September 2022

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Two-dimensional TiCT MXene promotes electrophysiological maturation of neural circuits.
Yige Li, Yangnan Hu, Hao Wei, Wei Cao, Yanru Qi, Huawei Li, Geng-Lin Li

J Nanobiotechnology· August 2022

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Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor.
Qingquan Xiao, Zhijiao Xu, Yuanyuan Xue, Chunlong Xu, Lei Han, Yuanhua Liu, Geng-Lin Li, Huawei Li

Sci Transl Med· July 2022

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Multiple Sevoflurane Exposures During the Neonatal Period Cause Hearing Impairment and Loss of Hair Cell Ribbon Synapses in Adult Mice.
Yufeng Li, Huiqian Yu, Xuehua Zhou, Lin Jin, Wen Li, Geng-Lin Li

Front Neurosci· July 2022

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