Publications by authors named "Genzoh Tanabe"

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Exploring the Substrate Flexibility of GrsB Thioesterase Leads to the Structural Reassignment of a Gramicidin S Variant.
Sho Konno, Tomoe Mizuguchi, Atsuko Suzuki, Miyu Tanaka, Fumihiro Ishikawa, Genzoh Tanabe

Chembiochem· November 2025

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Design and Synthesis of Sulfonium and Selenonium Derivatives Bearing 3',5'-O-Benzylidene Acetal Side Chains as Potent α-Glucosidase Inhibitors.
Yaojia Li, Jiahui Zhou, Xiaoxing Wu, Wei Li, Zhe Wang, Genzoh Tanabe

ChemMedChem· November 2025

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Synthesis of Neokotalanol and Its Derivatives as Potent α-Glucosidase Inhibitors.
Yaojia Li, Dan Liu, Xuezheng Zhao, Jiahui Zhou, Yu Li, Genzoh Tanabe

Org Lett· October 2025

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Design and Synthesis of Sulfonium and Selenonium Derivatives Bearing 3',5'--Benzylidene Acetal Side Chain Structure as Potent α-Glucosidase Inhibitors.
Xiaosong He, Jiahao Yi, Jianchen Yang, Genzoh Tanabe, Osamu Muraoka

Molecules· July 2025

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Calcium/Calmodulin-Dependent Protein Kinase II Inhibitors Mitigate High-Fat Diet-Induced Obesity in Mice.
Naoyuki Kawao, Ryosuke Satoh, Yuya Mizukami, Katsumi Okumoto, Genzoh Tanabe

J Obes· July 2025

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Degradation of Nonribosomal Peptide Synthetase Megasynthetases SrfAA and SrfAB by Acyldepsipeptide-Activated ClpP in Bacillus Subtilis.
Fumihiro Ishikawa, Chiharu Uchida, Rina Ohnishi, Taketo Imai, Genzoh Tanabe

Chembiochem· June 2025

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Inhibition of Surfactin Biosynthesis in Bacillus Subtilis Using Cell-Permeable Adenylation Domain Inhibitors.
Fumihiro Ishikawa, Sho Konno, Hideaki Kakeya, Genzoh Tanabe

Chembiochem· June 2025

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Synthesis and biological evaluation of γ-alkylidenebutenolides isolated from : the role of the propylidene-type side chain structure on anti-melanogenic activity.
Katsuki Takashima, Yoshiaki Manse, Riko Suzuki, Nanami Masuda, Yuki Fukuda, Genzoh Tanabe

Org Biomol Chem· May 2025

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Synthesis of trans-Fused 3,6-Anhydro Hexofuranose Frameworks via Catalytic Hydrogenolysis Triggered Debenzylative Intramolecular Acetalation.
Yu Li, Zhi-Mei Wang, Wen-Xiang Tao, Jian-Chen Yang, Genzoh Tanabe

ChemMedChem· April 2025

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Dynamic Oligomerization Processes of ClpP Protease Induced by ADEP1 Studied with High-Speed Atomic Force Microscopy.
Fumihiro Ishikawa, Kanji Takahashi, Akiko Takaya, Genzoh Tanabe, Michio Homma

ACS Omega· February 2025

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Biosynthetic Incorporation of Non-native Aryl Acid Building Blocks into Peptide Products Using Engineered Adenylation Domains.
Fumihiro Ishikawa, Maya Nohara, Akimasa Miyanaga, Satoki Kuramoto, Natsuki Miyano, Genzoh Tanabe

ACS Chem Biol· December 2024

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Protein degradation by a component of the chaperonin-linked protease ClpP.
Fumihiro Ishikawa, Michio Homma, Genzoh Tanabe, Takayuki Uchihashi

Genes Cells· September 2024

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Probing for optimal photoaffinity linkers of benzophenone-based photoaffinity probes for adenylating enzymes.
Sho Konno, Fumihiro Ishikawa, Hideaki Kakeya, Genzoh Tanabe

Bioorg Med Chem· August 2024

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Proteolytic Regulation in the Biosynthesis of Natural Product Via a ClpP Protease System.
Fumihiro Ishikawa, Chiharu Uchida, Genzoh Tanabe

ACS Chem Biol· August 2024

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Recent progress in the reprogramming of nonribosomal peptide synthetases.
Fumihiro Ishikawa, Shinya Nakamura, Isao Nakanishi, Genzoh Tanabe

J Pept Sci· March 2024

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Radical Nitrososulfonation of Propargyl Alcohols: Thiazolidine-2,4-dione-Assisted Synthesis of 5-Alykyl-4-sulfonylisoxazoles.
Tomoki Nakano, Nami Kousaka, Aoi Nakayama, Yoshiaki Kato, Katsuki Takashima, Genzoh Tanabe

Org Lett· March 2024

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ACA-28, an ERK MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic Cancer Cells.
Teruaki Takasaki, Yasuyuki Hamabe, Kenta Touchi, Golam Iftakhar Khandakar, Takeshi Ueda, Genzoh Tanabe

Oxid Med Cell Longev· March 2024

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[Protein degradation in bacteria: focus on the ClpP protease].
Fumihiro Ishikawa, Michio Homma, Genzoh Tanabe, Takayuki Uchihashi

Nihon Saikingaku Zasshi· February 2024

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Development of a chemical scaffold for inhibiting nonribosomal peptide synthetases in live bacterial cells.
Fumihiro Ishikawa, Sho Konno, Hideaki Kakeya, Genzoh Tanabe

Beilstein J Org Chem· February 2024

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Role of the thiosugar ring in the inhibitory activity of salacinol, a potent natural α-glucosidase inhibitor.
Katsuki Takashima, Shinya Nakamura, Maiko Nagayama, Shinsuke Marumoto, Fumihiro Ishikawa, Genzoh Tanabe

RSC Adv· January 2024

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Total Synthesis of Calanthoside, a Potential Hair Growth Stimulant: A Facile Synthetic Approach via One-Pot - and -Glucosidic Bond Formation.
Katsuki Takashima, Akane Asai, Mina Ashidate, Riko Suzuki, Shinsuke Marumoto, Genzoh Tanabe

J Nat Prod· December 2023

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Biosynthetic diversification of non-ribosomal peptides through activity-based protein profiling of adenylation domains.
Fumihiro Ishikawa, Natsumi Tsukumo, Erika Morishita, Shumpei Asamizu, Saaya Kusuhara, Genzoh Tanabe

Chem Commun (Camb)· August 2023

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ACAGT-007a, an anti-cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells.
Golam Iftakhar Khandakar, Yoichi Miyamoto, Ryosuke Satoh, Kenta Kishimoto, Mingzuo Xie, Genzoh Tanabe

Genes Cells· June 2023

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Chemoproteomic Profiling of Adenylation Domain Functions in Gramicidin S-Producing Non-ribosomal Peptide Synthetases.
Fumihiro Ishikawa, Genzoh Tanabe

Methods Mol Biol· May 2023

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Chemical Labeling of Protein 4'-Phosphopantetheinylation in Surfactin-Producing Nonribosomal Peptide Synthetases.
Fumihiro Ishikawa, Genzoh Tanabe

Methods Mol Biol· May 2023

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