Publications by authors named "Genzui Setsu"

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Pharmacological inhibition of HPK1 synergizes with PD-L1 blockade to provoke antitumor immunity against tumors with low antigenicity.
Genzui Setsu, Megumi Goto, Kentaro Ito, Tomoe Taira, Masaya Miyamoto

Biochem Biophys Res Commun· June 2024

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Highly potent, orally active novel small-molecule HPK1 inhibitor DS21150768 induces anti-tumor responses in multiple syngeneic tumor mouse models.
Genzui Setsu, Megumi Goto, Kentaro Ito, Tomoe Taira, Masaya Miyamoto

Eur J Pharmacol· December 2023

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Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor.
Ryutaro Kanada, Yoshiko Kagoshima, Takashi Suzuki, Akifumi Nakamura, Hideaki Funami, Genzui Setsu

J Med Chem· January 2023

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Gpr19 is a circadian clock-controlled orphan GPCR with a role in modulating free-running period and light resetting capacity of the circadian clock.
Yoshiaki Yamaguchi, Iori Murai, Kaoru Goto, Shotaro Doi, Huihua Zhou, Genzui Setsu

Sci Rep· November 2021

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Identification and functional characterisation of N-linked glycosylation of the orphan G protein-coupled receptor Gpr176.
Tianyu Wang, Shumpei Nakagawa, Takahito Miyake, Genzui Setsu, Sumihiro Kunisue

Sci Rep· March 2020

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Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour.
Masao Doi, Iori Murai, Sumihiro Kunisue, Genzui Setsu, Naohiro Uchio

Nat Commun· February 2016

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