Publications by authors named "Geoff Macintyre"

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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes.
Stefan C Dentro, Ignaty Leshchiner, Kerstin Haase, Maxime Tarabichi, Jeff Wintersinger, Amit G Deshwar, Kaixian Yu, Yulia Rubanova, Geoff Macintyre, Jonas Demeulemeester

Cell· April 2021

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A comprehensive genetic catalog of human double-strand break repair.
Ernesto López de Alba, Israel Salguero, Daniel Giménez-Llorente, Javier Montes-Torres, Ángel Fernández-Sanromán, Geoff Macintyre

Science· October 2025

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Predicting resistance to chemotherapy using chromosomal instability signatures.
Joe Sneath Thompson, Laura Madrid, Barbara Hernando, Carolin M Sauer, Maria Vias, Geoff Macintyre

Nat Genet· July 2025

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Inherited genome instability.
Jayne Y Hehir-Kwa, Geoff Macintyre

Science· January 2025

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scAbsolute: measuring single-cell ploidy and replication status.
Michael P Schneider, Amy E Cullen, Justina Pangonyte, Jason Skelton, Harvey Major, Geoff Macintyre

Genome Biol· March 2024

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Author Correction: The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma.
Philip Smith, Thomas Bradley, Lena Morrill Gavarró, Teodora Goranova, Darren P Ennis, Geoff Macintyre

Nat Commun· September 2023

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The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma.
Philip Smith, Thomas Bradley, Lena Morrill Gavarró, Teodora Goranova, Darren P Ennis, Geoff Macintyre

Nat Commun· July 2023

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High-grade serous ovarian carcinoma organoids as models of chromosomal instability.
Maria Vias, Lena Morrill Gavarró, Carolin M Sauer, Deborah A Sanders, Anna M Piskorz, Geoff Macintyre

Elife· May 2023

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A medley of resistance in ovarian cancers.
Barbara Hernando, Geoff Macintyre

Nat Genet· March 2023

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Author Correction: The evolutionary history of 2,658 cancers.
Moritz Gerstung, Clemency Jolly, Ignaty Leshchiner, Stefan C Dentro, Santiago Gonzalez, Geoff Macintyre

Nature· February 2023

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Author Correction: Inferring structural variant cancer cell fraction.
Marek Cmero, Ke Yuan, Cheng Soon Ong, Jan Schröder, , Geoff Macintyre

Nat Commun· December 2022

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Prognostic markers of inflammation in endometrioid and clear cell ovarian cancer.
Alejandro Gallego, Marta Mendiola, Barbara Hernando, Alberto Berjon, Alice Cadiz, Geoff Macintyre

Int J Gynecol Cancer· August 2022

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CNpare: matching DNA copy number profiles.
Blas Chaves-Urbano, Barbara Hernando, Maria J Garcia, Geoff Macintyre

Bioinformatics· July 2022

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A pan-cancer compendium of chromosomal instability.
Ruben M Drews, Barbara Hernando, Maxime Tarabichi, Kerstin Haase, Tom Lesluyes, Geoff Macintyre

Nature· June 2022

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MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer.
Patrick McCoy, Stefano Mangiola, Geoff Macintyre, Ryan Hutchinson, Ben Tran

Prostate Cancer Prostatic Dis· December 2021

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Loss of in Prostate Cancer Correlates With Clinical Response to Androgen Deprivation Therapy.
Marek Cmero, Natalie J Kurganovs, Ryan Stuchbery, Patrick McCoy, Corrina Grima, Geoff Macintyre

JCO Precis Oncol· June 2021

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FrenchFISH: Poisson Models for Quantifying DNA Copy Number From Fluorescence In Situ Hybridization of Tissue Sections.
Geoff Macintyre, Anna M Piskorz, Adam Berman, Edith Ross, David B Morse

JCO Clin Cancer Inform· February 2021

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Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).
Aline Talhouk, Joshy George, Chen Wang, Timothy Budden, Tuan Zea Tan, Geoff Macintyre

Clin Cancer Res· October 2020

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Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.
Alejandro Jiménez-Sánchez, Paulina Cybulska, Katherine LaVigne Mager, Simon Koplev, Oliver Cast, Geoff Macintyre

Nat Genet· June 2020

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Genomic landscape of platinum resistant and sensitive testicular cancers.
Chey Loveday, Kevin Litchfield, Paula Z Proszek, Alex J Cornish, Flavia Santo, Geoff Macintyre

Nat Commun· May 2020

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Inferring structural variant cancer cell fraction.
Marek Cmero, Ke Yuan, Cheng Soon Ong, Jan Schröder, , Geoff Macintyre

Nat Commun· February 2020

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Copy number signatures and mutational processes in ovarian carcinoma.
Geoff Macintyre, Teodora E Goranova, Dilrini De Silva, Darren Ennis, Anna M Piskorz

Nat Genet· September 2018

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Periprostatic fat tissue transcriptome reveals a signature diagnostic for high-risk prostate cancer.
Stefano Mangiola, Ryan Stuchbery, Geoff Macintyre, Michael J Clarkson, Justin S Peters

Endocr Relat Cancer· May 2018

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How Subclonal Modeling Is Changing the Metastatic Paradigm.
Geoff Macintyre, Peter Van Loo, Niall M Corcoran, David C Wedge, Florian Markowetz

Clin Cancer Res· February 2017

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