Publications by authors named "Geoffrey Candy"

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Identification of differentially expressed genes and associated immune cell types in South African gallbladder cancer patients.
John Devar, Pavan Baichan, Phelelani T Mpangase, Nnenna Elebo, Geoffrey Patrick Candy

Sci Rep· November 2025

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Distinct Metabolomic and Lipoprotein Signatures in Gall Bladder Cancer Patients of Black African Ancestry.
John Devar, Nnenna Elebo, Ashna Makan, Ariel Pincus, Nicola Lahoud, Geoffrey Candy

Cancers (Basel)· September 2025

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Comparative immune profiling of pancreatic ductal adenocarcinoma progression among South African patients.
Nnenna Elebo, Ebtesam A Abdel-Shafy, Jones A O Omoshoro-Jones, Zanele Nsingwane, Ahmed A A Hussein, Geoffrey Candy

BMC Cancer· July 2024

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Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry.
Pavan Baichan, Previn Naicker, Tanya Nadine Augustine, Martin Smith, Geoffrey Candy

Clin Proteomics· March 2023

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Serum Metabolomic and Lipoprotein Profiling of Pancreatic Ductal Adenocarcinoma Patients of African Ancestry.
Nnenna Elebo, Jones Omoshoro-Jones, Pascaline N Fru, John Devar, Christiaan De Wet van Zyl, Geoffrey Candy

Metabolites· September 2021

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Targeting Growth Factor Signaling Pathways in Pancreatic Cancer: Towards Inhibiting Chemoresistance.
Ntombikayise Xelwa, Geoffrey Patrick Candy, John Devar, Jones Omoshoro-Jones, Martin Smith

Front Oncol· June 2021

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SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways.
Ekene Emmanuel Nweke, Previn Naicker, Shaun Aron, Stoyan Stoychev, John Devar, Geoffrey Candy

PLoS One· December 2020

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Breast Cancer Cells Induce a Pro-inflammatory Response to Mitigate Immune Mediation in a 3D Culture Model.
Tanya N Augustine, Raquel Duarte, Geoffrey P Candy

Anticancer Res· November 2020

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Immunotherapeutic strategies in pancreatic ductal adenocarcinoma (PDAC): current perspectives and future prospects.
Zanele Nsingwane, Geoffrey Candy, John Devar, Jones Omoshoro-Jones, Martin Smith

Mol Biol Rep· August 2020

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Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma.
Ekene Nweke, Monde Ntwasa, Martin Brand, John Devar, Martin Smith, Geoffrey Candy

Oncol Lett· June 2020

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Transient Expression of Interleukin-21 in the Second Hit of Acute Pancreatitis May Potentiate Immune Paresis in Severe Acute Pancreatitis.
John-Edwin Thomson, Ekene E Nweke, Martin Brand, Marietha Nel, Geoffrey P Candy

Pancreas· January 2019

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The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output.
Morten Smerup, Mads Damkjær, Emil Brøndum, Ulrik T Baandrup, Steen Buus Kristiansen, Geoffrey Candy

J Exp Biol· February 2016

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Cystatin C- and creatinine-based equations in the assessment of renal function in HIV-positive patients prior to commencing Highly Active Antiretroviral Therapy.
Tebogo Seape, Verena Gounden, Hendrick E van Deventer, Geoffrey P Candy, Jaya A George

Ann Clin Biochem· January 2016

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Establishment of a heterotypic 3D culture system to evaluate the interaction of TREG lymphocytes and NK cells with breast cancer.
Tanya N Augustine, Thérèse Dix-Peek, Raquel Duarte, Geoffrey P Candy

J Immunol Methods· November 2015

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Lumbar disc replacement for junctional decompensation after fusion surgery: clinical and radiological outcome at an average follow-up of 33 months.
Ulrich R Hähnle, Karen Sliwa, Ian R Weinberg, Barry Mbe Sweet, Malan de Villiers, Geoffrey P Candy

SAS J· March 2015

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Is Degenerative Spondylolisthesis a Contraindication for Total Disc Replacement? Kineflex Lumbar Disc Replacement in 7 Patients With 24-Month Follow-up.
Ulrich R Hähnle, Karen Sliwa, Malan de Villiers, Ian R Weinberg, Barry M B E Sweet, Geoffrey P Candy

SAS J· March 2015

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Enuresis in South African children: prevalence, associated factors and parental perception of treatment.
Margaret W Fockema, Geoffrey P Candy, Deirdré Kruger, Mohamed Haffejee

BJU Int· December 2012

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Prevalence of residual left ventricular structural changes after one year of antihypertensive treatment in patients of African descent: role of 24-hour pulse pressure.
Elena N Libhaber, Gavin R Norton, Carlos D Libhaber, Angela J Woodiwiss, Geoffrey P Candy

Cardiovasc J Afr· April 2012

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Modeling of cellular arginine uptake by more than one transporter.
Marietha J Nel, Angela J Woodiwiss, Geoffrey P Candy

J Membr Biol· January 2012

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Multimodality scar management program.
Alan D Widgerow, Laurence A Chait, Pieter J Stals, Rene Stals, Geoffrey Candy

Aesthetic Plast Surg· July 2009

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Assessment of the medial head of the gastrocnemius muscle in functional compression of the popliteal artery.
Jayandiran Pillai, Lewis J Levien, Mark Haagensen, Geoffrey Candy, Michelle D V Cluver

J Vasc Surg· November 2008

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Lavage drain extension for local anaesthetic instillation into abdominal wounds.
Alan D Widgerow, Craig Wittstock, Geoffrey P Candy

S Afr J Surg· February 2008

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Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin.
Angela J Woodiwiss, Benedicta Nkeh, Nilesh J Samani, Danelle Badenhorst, Muzi Maseko, Geoffrey P Candy

J Hypertens· June 2006

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Impact of initiating carvedilol before angiotensin-converting enzyme inhibitor therapy on cardiac function in newly diagnosed heart failure.
Karen Sliwa, Gavin R Norton, Ngalulawa Kone, Geoffrey Candy, John Kachope

J Am Coll Cardiol· November 2004

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Effect of slow-release indapamide and perindopril compared with amlodipine on 24-hour blood pressure and left ventricular mass in hypertensive patients of African ancestry.
Elena N Libhaber, Carlos D Libhaber, Geoffrey P Candy, Karen Sliwa, John Kachope

Am J Hypertens· May 2004

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