Publications by authors named "Geoffrey Hart"

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Polymorphisms in Pfkelch13 domains before and after the introduction of artemisinin-based combination therapy in Southwest Nigeria.
Abiodun Amusan, Olugbenga Akinola, Kazeem Akano, María Hernández-Castañeda, Jenna K Dick, Geoffrey Hart

PLoS One· May 2025

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Phenotype and function of IL-10-producing NK cells in individuals with malaria experience.
Sarah A McNitt, Jenna K Dick, Maria Andrea Hernandez-Castaneda, Jules Sangala, Mark Pierson, Geoffrey T Hart

JCI Insight· May 2025

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Natural killer cell function in children with severe malaria differs according to malaria transmission intensity.
Grace Turyasingura, Kagan A Mellencamp, Ruth Namazzi, Robert O Opoka, Chandy C John, Geoffrey T Hart

bioRxiv· May 2025

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Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cells.
Jacob A Hildebrand, Noah R Daniels, Emma M Dehm, Benjamin D Fisher, Joseph K Guter, Geoffrey T Hart

PLoS Pathog· March 2025

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Frequency of chloroquine-resistant haplotype of Plasmodium falciparum (CVIET) in Ibadan, Southwest Nigeria 17 years post-chloroquine withdrawal.
Abiodun Amusan, Olugbenga Akinola, Kazeem Akano, María Hernández-Castañeda, Jenna K Dick, Geoffrey Hart

Acta Trop· December 2024

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NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children.
Jenna K Dick, Jules A Sangala, Venkatramana D Krishna, Aaron Khaimraj, Lydia Hamel, Geoffrey T Hart

J Immunol· November 2024

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Human ACE2 Gene Replacement Mice Support SARS-CoV-2 Viral Replication and Nonlethal Disease Progression.
Joshua M Thiede, Jenna K Dick, Nicholas N Jarjour, Venkatramana D Krishna, Lily Qian, Geoffrey T Hart

Immunohorizons· September 2024

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ACE2 decoy Fc-fusions and bi-specific killer engager (BiKEs) require Fc engagement for efficacy against SARS-CoV-2.
Jenna K Dick, Dustin Hicks, Venkatramana D Krishna, Jules A Sangala, Benjamin T Zandstra, Geoffrey T Hart

bioRxiv· June 2024

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Phenotype and function of IL-10 producing NK cells in individuals with malaria experience.
Sarah A McNitt, Jenna K Dick, Maria Hernandez Castaneda, Jules A Sangala, Mark Pierson, Geoffrey T Hart

bioRxiv· May 2024

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Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C).
Jenna K Dick, Jules A Sangala, Venkatramana D Krishna, Aaron Khaimraj, Lydia Hamel, Geoffrey T Hart

bioRxiv· April 2024

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iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting.
Kristin M Snyder, Kate J Dixon, Zachary Davis, Martin Hosking, Geoffrey Hart

J Immunother Cancer· December 2023

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NK cell subsets and dysfunction during viral infection: a new avenue for therapeutics?
Jacob C Bjorgen, Jenna K Dick, Ross Cromarty, Geoffrey T Hart, Joshua Rhein

Front Immunol· November 2023

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Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production.
James D Dahlvang, Jenna K Dick, Jules A Sangala, Philippa R Kennedy, Emily J Pomeroy, Geoffrey T Hart

J Immunol· April 2023

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Natural Killer Cell Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity Against Plasmodium falciparum-Infected Red Blood Cells.
Jenna Kelly Dick, Geoffrey Thomas Hart

Methods Mol Biol· July 2022

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Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial.
Jeffrey S Miller, Zachary B Davis, Erika Helgeson, Cavan Reilly, Ann Thorkelson, Geoffrey T Hart

Nat Med· February 2022

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Simultaneous Engagement of Tumor and Stroma Targeting Antibodies by Engineered NK-92 Cells Expressing CD64 Controls Prostate Cancer Growth.
Hallie M Hintz, Kristin M Snyder, Jianming Wu, Robert Hullsiek, James D Dahlvang, Geoffrey T Hart

Cancer Immunol Res· November 2021

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Contribution of Antibody-Mediated Effector Functions to the Mechanism of Efficacy of Vaccines for Opioid Use Disorders.
April M Huseby Kelcher, Carly A Baehr, Fatima A Hamid, Geoffrey T Hart, Marco Pravetoni

J Immunol· August 2021

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Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses.
Vineet Joag, Sathi Wijeyesinghe, J Michael Stolley, Clare F Quarnstrom, Thamotharampillai Dileepan, Geoffrey T Hart

J Immunol· March 2021

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Patients With Natural Killer (NK) Cell Chronic Active Epstein-Barr Virus Have Immature NK Cells and Hyperactivation of PI3K/Akt/mTOR and STAT1 Pathways.
Matthew K Howe, Kennichi Dowdell, Hye Sun Kuehn, Qingxue Li, Geoffrey T Hart

J Infect Dis· September 2020

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Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations.
Mary S Pampusch, Kumudhini Preethi Haran, Geoffrey T Hart, Eva G Rakasz, Aaron K Rendahl

Mol Ther Methods Clin Dev· March 2020

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A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation.
Tuan M Tran, Rajan Guha, Silvia Portugal, Jeff Skinner, Aissata Ongoiba, Geoffrey T Hart

Immunity· October 2019

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Contributions of natural killer cells to the immune response against Plasmodium.
Kristina S Burrack, Geoffrey T Hart, Sara E Hamilton

Malar J· September 2019

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Adaptive NK cells in people exposed to correlate with protection from malaria.
Geoffrey T Hart, Tuan M Tran, Jakob Theorell, Heinrich Schlums, Gunjan Arora

J Exp Med· June 2019

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NK cells inhibit growth in red blood cells via antibody-dependent cellular cytotoxicity.
Gunjan Arora, Geoffrey T Hart, Javier Manzella-Lapeira, Justin Ya Doritchamou, David L Narum

Elife· June 2018

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Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells.
Kristina S Burrack, Matthew A Huggins, Emily Taras, Philip Dougherty, Christine M Henzler, Geoffrey T Hart

Immunity· April 2018

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