Publications by authors named "Geoffrey J Topping"

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Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging.
Athanasia Kaika, Luca Nagel, Ulrike Höckendorf, Bangwen Xie, Geoffrey J Topping

Adv Sci (Weinh)· December 2025

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3D virtual biopsy of in vivo pH and metabolism using PRESS and semi-LASER MRS of hyperpolarized C nuclei.
Wolfgang Gottwald, Luca Nagel, Martin Grashei, Sebastian Bauer, Nadine Setzer, Geoffrey J Topping

Magn Reson Med· September 2025

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Correction to: Functional biomarkers derived from computed tomography and magnetic resonance imaging differentiate PDAC subgroups and reveal gemcitabine‑induced hypo‑vascularization.
Irina Heid, Marija Trajkovic-Arsic, Fabian Lohöfer, Georgios Kaissis, Felix N Harder, Geoffrey J Topping

Eur J Nucl Med Mol Imaging· August 2025

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Temperature dependent chemical shifts of pyruvate and lactate enable in vivo hyperpolarized C MRSI thermometry.
Wolfgang Gottwald, Luca Nagel, Jason G Skinner, Martin Grashei, Sandra Sühnel, Geoffrey J Topping

Npj Imaging· May 2025

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Filter-exchange spectroscopy is sensitive to gradual cell membrane degradation.
Athanasia Kaika, Geoffrey J Topping, Luca Nagel, Franz Schilling

NMR Biomed· November 2024

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Novel Tumor Organoid-Based Mouse Model to Study Image Guided Radiation Therapy of Rectal Cancer After Noninvasive and Precise Endoscopic Implantation.
Hannah Felchle, Valentina Brunner, Tanja Groll, Caroline N Walther, Sophie M Nefzger, Geoffrey J Topping

Int J Radiat Oncol Biol Phys· March 2024

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Repeatability and reproducibility of apparent exchange rate measurements in yeast cell phantoms using filter-exchange imaging.
Mathias Schillmaier, Athanasia Kaika, Geoffrey J Topping, Rickmer Braren, Franz Schilling

MAGMA· December 2023

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Parahydrogen-Polarized [1- C]Pyruvate for Reliable and Fast Preclinical Metabolic Magnetic Resonance Imaging.
Luca Nagel, Martin Gierse, Wolfgang Gottwald, Zumrud Ahmadova, Martin Grashei, Geoffrey J Topping

Adv Sci (Weinh)· October 2023

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Spectrally selective bSSFP using off-resonant RF excitations permits high spatiotemporal resolution 3D metabolic imaging of hyperpolarized [1- C]Pyruvate-to-[1- C]lactate conversion.
Jason G Skinner, Geoffrey J Topping, Luca Nagel, Irina Heid, Christian Hundshammer

Magn Reson Med· September 2023

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Functional biomarkers derived from computed tomography and magnetic resonance imaging differentiate PDAC subgroups and reveal gemcitabine-induced hypo-vascularization.
Irina Heid, Marija Trajkovic-Arsic, Fabian Lohöfer, Georgios Kaissis, Felix N Harder, Geoffrey J Topping

Eur J Nucl Med Mol Imaging· December 2022

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Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma.
Irina Heid, Corinna Münch, Sinan Karakaya, Smiths S Lueong, Alina M Winkelkotte, Geoffrey J Topping

Cancer Metab· December 2022

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Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages.
Zohreh Varasteh, Miriam Braeuer, Sarajo Mohanta, Anna-Lena Steinsiek, Andreas Habenicht, Geoffrey J Topping

Front Cardiovasc Med· April 2022

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Proof of concept of a multimodal intravital molecular imaging system for tumour transpathology investigation.
Zhen Liu, Tao Cheng, Stephan Düwel, Ziying Jian, Geoffrey J Topping

Eur J Nucl Med Mol Imaging· March 2022

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Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties.
Marie N M Volmar, Jiying Cheng, Haitham Alenezi, Sven Richter, Alisha Haug, Geoffrey J Topping

Neuro Oncol· November 2021

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Visualization of USPIO-labeled melt-electrowritten scaffolds by non-invasive magnetic resonance imaging.
Kilian M A Mueller, Geoffrey J Topping, Sebastian P Schwaminger, Younzhe Zou, Diana M Rojas-González

Biomater Sci· July 2021

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pH Dependence of for Hyperpolarizable C-Labelled Small Molecules Enables Spatially Resolved pH Measurement by Magnetic Resonance Imaging.
Martin Grashei, Christian Hundshammer, Frits H A van Heijster, Geoffrey J Topping, Franz Schilling

Pharmaceuticals (Basel)· April 2021

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Hyperpolarized C Spectroscopy with Simple Slice-and-Frequency-Selective Excitation.
Geoffrey J Topping, Irina Heid, Marija Trajkovic-Arsic, Lukas Kritzner, Martin Grashei

Biomedicines· January 2021

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Acquisition strategies for spatially resolved magnetic resonance detection of hyperpolarized nuclei.
Geoffrey J Topping, Christian Hundshammer, Luca Nagel, Martin Grashei, Maximilian Aigner

MAGMA· April 2020

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SNR analysis of contrast-enhanced MR imaging for early detection of rheumatoid arthritis.
Florian T Gassert, Felix G Gassert, Geoffrey J Topping, Ernst J Rummeny, Moritz Wildgruber

PLoS One· November 2019

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Manganese concentration mapping in the rat brain with MRI, PET, and autoradiography.
Geoffrey J Topping, Andrew Yung, Paul Schaffer, Cornelia Hoehr, Rick Kornelsen

Med Phys· August 2017

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Manganese-52 positron emission tomography tracer characterization and initial results in phantoms and in vivo.
Geoffrey J Topping, Paul Schaffer, Cornelia Hoehr, Thomas J Ruth, Vesna Sossi

Med Phys· April 2013

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Positron emission tomography kinetic modeling algorithms for small animal dopaminergic system imaging.
Geoffrey J Topping, Katie Dinelle, Rick Kornelsen, Siobhan McCormick, James E Holden

Synapse· March 2010

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Dopamine transporter relation to levodopa-derived synaptic dopamine in a rat model of Parkinson's: an in vivo imaging study.
Vesna Sossi, Katherine Dinelle, Geoffrey J Topping, James E Holden, Doris Doudet

J Neurochem· April 2009

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In vivo measurement of density and affinity of the monoamine vesicular transporter in a unilateral 6-hydroxydopamine rat model of PD.
Vesna Sossi, James E Holden, Geoffrey J Topping, Marie-Laure Camborde, Rich A Kornelsen

J Cereb Blood Flow Metab· July 2007

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