Publications by authors named "Geoffrey Matthews"

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Highly specific intracellular ubiquitination of a small molecule.
Weicheng Li, Enrique M Garcia-Rivera, Dylan C Mitchell, Joel M Chick, Micah Maetani, Geoffrey M Matthews

Nat Chem Biol· August 2025

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Highly specific intracellular ubiquitination of a small molecule.
Weicheng Li, Enrique M Garcia-Rivera, Dylan C Mitchell, Joel M Chick, Micah Maetani, Geoffrey M Matthews

bioRxiv· January 2024

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Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L Downey-Kopyscinski, Geoffrey M Matthews, Benjamin G Barwick

Nat Cancer· May 2023

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Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins.
Ryosuke Shirasaki, Geoffrey M Matthews, Sara Gandolfi, Ricardo de Matos Simoes, Dennis L Buckley

Cell Rep· January 2021

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Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.
Marcus Lefebure, Richard W Tothill, Elizabeth Kruse, Edwin D Hawkins, Jake Shortt, Geoffrey M Matthews

Nat Commun· March 2017

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Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.
Najoua Lalaoui, Kay Hänggi, Gabriela Brumatti, Diep Chau, Nhu-Y N Nguyen, Geoffrey M Matthews

Cancer Cell· September 2016

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NF-κB dysregulation in multiple myeloma.
Geoffrey M Matthews, Ricardo de Matos Simoes, Eugen Dhimolea, Michal Sheffer, Sara Gandolfi

Semin Cancer Biol· August 2016

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Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.
Najoua Lalaoui, Kay Hänggi, Gabriela Brumatti, Diep Chau, Nhu-Y N Nguyen, Geoffrey M Matthews

Cancer Cell· February 2016

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Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Geoffrey M Matthews, Parinaz Mehdipour, Leonie A Cluse, Katrina J Falkenberg, Eric Wang

Blood· November 2015

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Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers.
Jennifer A Westwood, Geoffrey M Matthews, Jake Shortt, David Faulkner, Hollie J Pegram

Leuk Res· August 2014

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The drug vehicle and solvent N-methylpyrrolidone is an immunomodulator and antimyeloma compound.
Jake Shortt, Andy K Hsu, Benjamin P Martin, Karen Doggett, Geoffrey M Matthews

Cell Rep· May 2014

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Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities.
Andrea Newbold, Geoffrey M Matthews, Michael Bots, Leonie A Cluse, Christopher J P Clarke

Mol Cancer Ther· December 2013

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A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.
Fabio Santoro, Oronza A Botrugno, Roberto Dal Zuffo, Isabella Pallavicini, Geoffrey M Matthews

Blood· April 2013

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Intrinsic and extrinsic apoptotic pathway signaling as determinants of histone deacetylase inhibitor antitumor activity.
Geoffrey M Matthews, Andrea Newbold, Ricky W Johnstone

Adv Cancer Res· March 2013

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Short-chain fatty acids induce apoptosis in colon cancer cells associated with changes to intracellular redox state and glucose metabolism.
Geoffrey M Matthews, Gordon S Howarth, Ross N Butler

Chemotherapy· October 2012

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NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.
Stephen R Mattarollo, Alison C West, Kim Steegh, Helene Duret, Christophe Paget, Geoffrey M Matthews

Blood· October 2012

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Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy.
Marta Chesi, Geoffrey M Matthews, Victoria M Garbitt, Stephen E Palmer, Jake Shortt

Blood· July 2012

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Rapid hypnosis as an anaesthesia adjunct for evacuation of postpartum vulval haematoma.
Lufee Wong, Allan M Cyna, Geoffrey Matthews

Aust N Z J Obstet Gynaecol· June 2011

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Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine.
Sandra Hodge, Geoffrey Matthews, Violet Mukaro, Jessica Ahern, Aruna Shivam

Am J Respir Cell Mol Biol· May 2011

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Therapeutic role for mannose-binding lectin in cigarette smoke-induced lung inflammation? Evidence from a murine model.
Sandra Hodge, Geoffrey Matthews, Melinda M Dean, Jessica Ahern, Michael Djukic

Am J Respir Cell Mol Biol· February 2010

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Glucose absorption and gastric emptying in critical illness.
Marianne J Chapman, Robert J L Fraser, Geoffrey Matthews, Antonietta Russo, Max Bellon

Crit Care· January 2010

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Azithromycin improves macrophage phagocytic function and expression of mannose receptor in chronic obstructive pulmonary disease.
Sandra Hodge, Greg Hodge, Hubertus Jersmann, Geoffrey Matthews, Jessica Ahern

Am J Respir Crit Care Med· July 2008

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Association between intrarenal arterial resistance and diastolic dysfunction in type 2 diabetes.
Richard J MacIsaac, Merlin C Thomas, Sianna Panagiotopoulos, Trudy J Smith, Huming Hao, D Geoffrey Matthews

Cardiovasc Diabetol· May 2008

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Short-chain fatty acid modulation of apoptosis in the Kato III human gastric carcinoma cell line.
Geoffrey M Matthews, Gordon S Howarth, Ross N Butler

Cancer Biol Ther· July 2007

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Is nonalbuminuric renal insufficiency in type 2 diabetes related to an increase in intrarenal vascular disease?
Richard J MacIsaac, Sianna Panagiotopoulos, Karen J McNeil, Trudy J Smith, Con Tsalamandris, P Geoffrey Matthews

Diabetes Care· July 2006

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