Publications by authors named "Georg Halder"

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Steatotic liver disease induces YAP/TAZ-driven cell competition that can suppress tumor initiation.
Ana Algueró-Nadal, Hasse Mol, Elena Zoppolato, Weronika Kowalczyk, Leticia Sansores-García, Georg Halder

J Hepatol· November 2025

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In Vivo Tracking and 3D Mapping of Cell Death in Regeneration and Cancer Using Trypan Blue.
Nicole Procel, Karen Camacho, Elisabeth Verboven, Isabel Baroja, Priscila A Guerrero, Georg Halder

Cells· August 2024

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Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer.
Isabel Baroja, Nikolaos C Kyriakidis, Georg Halder, Iván M Moya

Nat Commun· March 2024

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A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models.
Hanne Hillen, Aurélie Candi, Bart Vanderhoydonck, Weronika Kowalczyk, Leticia Sansores-Garcia, Georg A Halder

Mol Cancer Ther· January 2024

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Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation.
Carmen Bravo González-Blas, Irina Matetovici, Hanne Hillen, Ibrahim Ihsan Taskiran, Roel Vandepoel, Georg Halder

Nat Cell Biol· January 2024

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Shared enhancer gene regulatory networks between wound and oncogenic programs.
Swann Floc'hlay, Ramya Balaji, Dimitrije Stanković, Valerie M Christiaens, Carmen Bravo González-Blas, Georg Halder

Elife· May 2023

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Initiation of hepatic stellate cell activation extends into chronic liver disease.
Vincent De Smet, Nathalie Eysackers, Vincent Merens, Mina Kazemzadeh Dastjerd, Georg Halder

Cell Death Dis· November 2021

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A Mouse Model of Cholangiocarcinoma Uncovers a Role for Tensin-4 in Tumor Progression.
Mickaël Di-Luoffo, Sophie Pirenne, Thoueiba Saandi, Axelle Loriot, Claude Gérard, Georg Halder

Hepatology· September 2021

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Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis.
Elisabeth Verboven, Iván M Moya, Leticia Sansores-Garcia, Jun Xie, Hanne Hillen, Georg Halder

Gastroenterology· February 2021

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Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.
Iván M Moya, Stéphanie A Castaldo, Laura Van den Mooter, Soheil Soheily, Leticia Sansores-Garcia, Georg Halder

Science· November 2019

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Hippo-YAP/TAZ signalling in organ regeneration and regenerative medicine.
Iván M Moya, Georg Halder

Nat Rev Mol Cell Biol· April 2019

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Comparison of the and Drivers in Bile Ducts of Normal and Injured Mouse Livers.
Bram Lesaffer, Elisabeth Verboven, Leen Van Huffel, Iván M Moya, Leo A van Grunsven, Georg Halder

Cells· April 2019

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YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role.
Matthias Van Haele, Iván M Moya, Ruçhan Karaman, Guy Rens, Janne Snoeck, Georg Halder

Int J Mol Sci· February 2019

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Modulation of the Hippo pathway and organ growth by RNA processing proteins.
Jana Mach, Mardelle Atkins, Kathleen M Gajewski, Violaine Mottier-Pavie, Leticia Sansores-Garcia, Georg Halder

Proc Natl Acad Sci U S A· October 2018

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The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models.
Carmen Vicente, Rocco Stirparo, Sofie Demeyer, Charles E de Bock, Olga Gielen, Georg Halder

J Hematol Oncol· August 2018

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The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes.
Jelle Jacobs, Mardelle Atkins, Kristofer Davie, Hana Imrichova, Lucia Romanelli, Georg Halder

Nat Genet· July 2018

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Cell Junctions in Hippo Signaling.
Ruchan Karaman, Georg Halder

Cold Spring Harb Perspect Biol· May 2018

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YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis.
Xiaohong Wang, Aida Freire Valls, Géza Schermann, Ying Shen, Ivan M Moya, Georg Halder

Dev Cell· September 2017

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Hippo Reprograms the Transcriptional Response to Ras Signaling.
Justine Pascual, Jelle Jacobs, Leticia Sansores-Garcia, Malini Natarajan, Julia Zeitlinger, Georg Halder

Dev Cell· September 2017

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The Hippo pathway in cellular reprogramming and regeneration of different organs.
Iván M Moya, Georg Halder

Curr Opin Cell Biol· December 2016

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An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model.
Mardelle Atkins, Delphine Potier, Lucia Romanelli, Jelle Jacobs, Jana Mach, Georg Halder

Curr Biol· August 2016

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MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway.
Zhipeng Meng, Toshiro Moroishi, Violaine Mottier-Pavie, Steven W Plouffe, Carsten G Hansen, Georg Halder

Nat Commun· October 2015

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The Hippo pathway effector YAP controls mouse hepatic stellate cell activation.
Inge Mannaerts, Sofia Batista Leite, Stefaan Verhulst, Sofie Claerhout, Nathalie Eysackers, Georg Halder

J Hepatol· September 2015

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Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state.
Annelien Verfaillie, Hana Imrichova, Zeynep Kalender Atak, Michael Dewaele, Florian Rambow, Georg Halder

Nat Commun· April 2015

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Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling.
Kristofer Davie, Jelle Jacobs, Mardelle Atkins, Delphine Potier, Valerie Christiaens, Georg Halder

PLoS Genet· February 2015

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