Publications by authors named "George Grayson"

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Synthesis and evaluation of 2-amido-3-carboxamide thiophene CB₂ receptor agonists for pain management.
Derek W Nelson, Jennifer M Frost, Karin R Tietje, Alan S Florjancic, Keith Ryther, George K Grayson

Bioorg Med Chem Lett· April 2012

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Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity.
Jennifer M Frost, Michael J Dart, Karin R Tietje, Tiffany R Garrison, George K Grayson

J Med Chem· January 2010

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A study of the adhesion between dental cement and dentin using a nondestructive acoustic microscopy approach.
Liudmila A Denisova, Roman Gr Maev, Valery K Leontjev, Alexandre F Denisov, George G Grayson

Dent Mater· May 2009

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Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models, and pharmacological magnetic resonance imaging.
Betty B Yao, Gin Hsieh, Anthony V Daza, Yihong Fan, George K Grayson

J Pharmacol Exp Ther· January 2009

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Characterization of human cannabinoid CB2 receptor coupled to chimeric Galpha(qi5) and Galpha(qo5) proteins.
John Malysz, Anthony V Daza, Karen Kage, George K Grayson, Betty B Yao

Eur J Pharmacol· January 2009

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Structure-activity relationship studies on N'-aryl carbohydrazide P2X7 antagonists.
Derek W Nelson, Kathy Sarris, Douglas M Kalvin, Marian T Namovic, George Grayson

J Med Chem· May 2008

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Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists.
Alan S Florjancic, Sridhar Peddi, Arturo Perez-Medrano, Biqin Li, Marian T Namovic, George Grayson

Bioorg Med Chem Lett· March 2008

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Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity.
Jennifer M Frost, Michael J Dart, Karin R Tietje, Tiffany R Garrison, George K Grayson

J Med Chem· March 2008

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Novel and potent 3-(2,3-dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 antagonists.
William A Carroll, Douglas M Kalvin, Arturo Perez Medrano, Alan S Florjancic, Ying Wang, George Grayson

Bioorg Med Chem Lett· July 2007

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Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists.
Derek W Nelson, Robert J Gregg, Michael E Kort, Arturo Perez-Medrano, Eric A Voight, George Grayson

J Med Chem· June 2006

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Preclinical profiling and safety studies of ABT-769: a compound with potential for broad-spectrum antiepileptic activity.
William J Giardina, Michael J Dart, Richard R Harris, Robert S Bitner, Richard J Radek, George K Grayson

Epilepsia· September 2005

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ABT-963 [2-(3,4-difluoro-phenyl)-4-(3-hydroxy-3-methyl-butoxy)-5-(4-methanesulfonyl-phenyl)-2H-pyridazin-3-one], a highly potent and selective disubstituted pyridazinone cyclooxgenase-2 inhibitor.
Richard R Harris, Lawrence Black, Sekhar Surapaneni, Teodozyj Kolasa, Sandra Majest, George Grayson

J Pharmacol Exp Ther· December 2004

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Identification and characterization of novel antagonists of the CCR3 receptor.
Usha Warrior, Evelyn M McKeegan, Susan M Rottinghaus, Lora Garcia, Linda Traphagen, George Grayson

J Biomol Screen· June 2003

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