Publications by authors named "George Grosu"

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The fractal brain: scale-invariance in structure and dynamics.
George F Grosu, Alexander V Hopp, Vasile V Moca, Harald Bârzan, Andrei Ciuparu

Cereb Cortex· April 2023

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The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists.
Wayne E Childers, Lisa M Havran, Magda Asselin, James J Bicksler, Dan C Chong, George T Grosu

J Med Chem· May 2010

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The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1).
Thomas Nittoli, Russell G Dushin, Charles Ingalls, Katherine Cheung, M Brawner Floyd, George Grosu

Eur J Med Chem· April 2010

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Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR).
Hwei-Ru Tsou, Gloria MacEwan, Gary Birnberg, George Grosu, Matthew G Bursavich

Bioorg Med Chem Lett· April 2010

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(4-Substituted-phenyl)-(5H-10,11-dihydro-pyrrolo [2,1-c][1,4] benzodiazepin-10-yl)-methanone derivatives as vasopressin receptor modulators.
Aranapakam M Venkatesan, George T Grosu, Amedeo A Failli, Peter S Chan, Joseph Coupet

Bioorg Med Chem Lett· November 2005

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Synthesis and structure-activity relationships of 4-alkynyloxy phenyl sulfanyl, sulfinyl, and sulfonyl alkyl hydroxamates as tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase inhibitors.
Aranapakam M Venkatesan, Jamie M Davis, George T Grosu, Jannie Baker, Arie Zask

J Med Chem· December 2004

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Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists.
Fuk Wah Sum, John Dusza, Efren Delos Santos, George Grosu, Marvin Reich

Bioorg Med Chem Lett· July 2003

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Synthesis and structure-activity relationship of alpha-sulfonylhydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis.
Venkatesan Aranapakam, George T Grosu, Jamie M Davis, Baihua Hu, John Ellingboe

J Med Chem· June 2003

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Synthesis and structure-activity relationship of N-substituted 4-arylsulfonylpiperidine-4-hydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis.
Venkatesan Aranapakam, Jamie M Davis, George T Grosu, Jannie Baker, John Ellingboe

J Med Chem· June 2003

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