Publications by authors named "George Harb"

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Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report.
Ashley M Fortress, Kiyoharu J Miyagishima, Amberlynn A Reed, Sally Temple, Dennis O Clegg, George Harb

Stem Cell Res Ther· March 2023

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A Dual Inhibitor of DYRK1A and GSK3β for β-Cell Proliferation: Aminopyrazine Derivative GNF4877.
Yahu A Liu, Qihui Jin, Qiang Ding, Xueshi Hao, Tingting Mo, George Harb

ChemMedChem· August 2020

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Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133.
Yahu A Liu, Qihui Jin, Yefen Zou, Qiang Ding, Shanshan Yan, George Harb

J Med Chem· March 2020

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Charting cellular identity during human in vitro β-cell differentiation.
Adrian Veres, Aubrey L Faust, Henry L Bushnell, Elise N Engquist, Jennifer Hyoje-Ryu Kenty, George Harb

Nature· May 2019

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Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.
Peng Wang, Esra Karakose, Hongtao Liu, Ethan Swartz, Courtney Ackeifi, George Harb

Cell Metab· March 2019

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The Safety and Tolerability of 5-Aminolevulinic Acid Phosphate with Sodium Ferrous Citrate in Patients with Type 2 Diabetes Mellitus in Bahrain.
Feryal Al-Saber, Waleed Aldosari, Mariam Alselaiti, Hesham Khalfan, Ahmed Kaladari, George Harb

J Diabetes Res· June 2017

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Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
Weijun Shen, Brandon Taylor, Qihui Jin, Van Nguyen-Tran, Shelly Meeusen, George Harb

Nat Commun· October 2015

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Cost-effectiveness of recombinant human hyaluronidase-facilitated subcutaneous versus intravenous rehydration in children with mild to moderate dehydration.
Sharon E Mace, George Harb, Keith Friend, Robin Turpin, Edward P Armstrong

Am J Emerg Med· June 2013

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Small-molecule inducer of β cell proliferation identified by high-throughput screening.
Weijun Shen, Matthew S Tremblay, Vishal A Deshmukh, Weidong Wang, Christophe M Filippi, George Harb

J Am Chem Soc· February 2013

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A randomized clinical trial of recombinant human hyaluronidase-facilitated subcutaneous versus intravenous rehydration in mild to moderately dehydrated children in the emergency department.
Philip R Spandorfer, Sharon E Mace, Pamela J Okada, Harold K Simon, Coburn H Allen, George Harb

Clin Ther· November 2012

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Techniques for hyaluronidase-facilitated subcutaneous fluid administration with recombinant human hyaluronidase: the increased flow utilizing subcutaneously enabled administration technique (INFUSE AT) study.
Sandra Connolly, Helen Korzemba, George Harb, Francois Lebel, Christine Syltevik

J Infus Nurs· January 2012

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Parathyroid hormone-related protein enhances human ß-cell proliferation and function with associated induction of cyclin-dependent kinase 2 and cyclin E expression.
Nagesha Guthalu Kondegowda, Sheela Joshi-Gokhale, George Harb, Katoura Williams, Xiao Ying Zhang

Diabetes· December 2010

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Safety and pharmacokinetics of subcutaneous ceftriaxone administered with or without recombinant human hyaluronidase (rHuPH20) versus intravenous ceftriaxone administration in adult volunteers.
George Harb, Francois Lebel, Jean Battikha, Jeffrey W Thackara

Curr Med Res Opin· February 2010

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Recombinant human hyaluronidase-enabled subcutaneous pediatric rehydration.
Coburn H Allen, Lisa S Etzwiler, Melissa K Miller, George Maher, Sharon Mace, George Harb

Pediatrics· November 2009

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The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.
George Harb, Rupangi C Vasavada, David Cobrinik, Andrew F Stewart

Diabetes· August 2009

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Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo.
Nathalie Fiaschi-Taesch, Todd A Bigatel, Brian Sicari, Karen K Takane, Fatima Salim, George Harb

Diabetes· April 2009

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Marginal mass islet transplantation with autologous mesenchymal stem cells promotes long-term islet allograft survival and sustained normoglycemia.
Mario G Solari, Suganya Srinivasan, Imene Boumaza, Jignesh Unadkat, George Harb

J Autoimmun· March 2009

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Prolonged survival of microencapsulated neonatal porcine islet xenografts in immune-competent mice without antirejection therapy.
Tsunehiro Kobayashi, Hossein Arefanian, George Harb, Eric B Tredget, Ray V Rajotte

Cell Transplant· February 2009

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Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines.
Irene Cozar-Castellano, George Harb, Karen Selk, Karen Takane, Rupangi Vasavada

Diabetes· November 2008

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Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels.
Nicola J Webster, Gavin J Searle, Patrick P L Lam, Ya-Chi Huang, Michael J Riedel, George Harb

Endocrinology· July 2008

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Treatment of obesity and diabetes in mice by transplant of gut cells engineered to produce leptin.
Sarah N Oosman, Ada W Lam, George Harb, Suraj Unniappan, Ni T Lam

Mol Ther· June 2008

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Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial.
Jinlin Hou, You-Kuan Yin, Daozhen Xu, Deming Tan, Junqi Niu, George Harb

Hepatology· February 2008

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Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial.
Henry L Y Chan, E Jenny Heathcote, Patrick Marcellin, Ching-Lung Lai, Mong Cho, George Harb

Ann Intern Med· December 2007

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Acute exposure to streptozotocin but not human proinflammatory cytokines impairs neonatal porcine islet insulin secretion in vitro but not in vivo.
George Harb, Jeff Toreson, Janette Dufour, Gregory Korbutt

Xenotransplantation· November 2007

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Effect of prolonged in vitro exposure to high glucose on neonatal porcine pancreatic islets.
George Harb, Gregory S Korbutt

J Endocrinol· October 2006

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