Publications by authors named "George Miles"

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Integrative Proteogenomics and Forward Genetics Reveal a Novel Mitotic Vulnerability in Triple-Negative Breast Cancer.
Nicholas J Neill, Shankha Satpathy, Karsten Krug, Jitendra K Meena, Nivetha Ramesh Babu, George Miles

Cancer Discov· November 2025

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Germline Cancer Predisposition Results From the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
Sarah Scollon, Sharon E Plon, Steven Joffe, Jaclyn A Biegel, Shashikant Kulkarni, George Miles

JCO Precis Oncol· October 2025

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Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization.
Fengshuo Liu, Yunfeng Ding, Zhan Xu, Xiaoxin Hao, Tianhong Pan, George Miles

Cell Genom· July 2025

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Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers.
Eric J Jaehnig, Aranzazu Fernandez-Martinez, Tanmayi D Vashist, Matthew V Holt, LaTerrica Williams, George Miles

Cell Rep Med· June 2025

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Anaplastic meningioma in a 6-year-old with somatic YAP1::MAML2 fusion and multiple endocrine neoplasia type 4 (MEN4) syndrome.
Lauren R Desrosiers-Battu, John H Lee, Izabela Tarasiewicz, Andrea R Gilbert, Eva M Galvan, George Miles

Cancer Genet· April 2025

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IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer.
Longyong Xu, Fanglue Peng, Qin Luo, Yao Ding, Fei Yuan, George Miles

Cell· December 2024

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Comparing the Diagnostic Yield of Germline Exome Versus Panel Sequencing in the Diverse Population of the Texas KidsCanSeq Pediatric Cancer Study.
Lauren R Desrosiers-Battu, Tao Wang, Jacquelyn Reuther, George Miles, Hongzheng Dai

JCO Precis Oncol· September 2024

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Validation of an Integrated Genetic-Epigenetic Test for the Assessment of Coronary Heart Disease.
Robert Philibert, Timur K Dogan, Stacey Knight, Ferhaan Ahmad, Stanley Lau, George Miles

J Am Heart Assoc· November 2023

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Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors.
Xiangdong Lv, Xuan Lu, Jin Cao, Qin Luo, Yao Ding, George Miles

Science· September 2023

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Proteogenomic Approaches for the Identification of NF1/Neurofibromin-depleted Estrogen Receptor-positive Breast Cancers for Targeted Treatment.
Beom-Jun Kim, Ze-Yi Zheng, Jonathan T Lei, Matthew V Holt, Anran Chen, George Miles

Cancer Res Commun· July 2023

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Short-term PI3K Inhibition Prevents Breast Cancer in Preclinical Models.
Amy T Ku, Adelaide I J Young, Ahmed Atef Ibrahim, Wen Bu, Weiyu Jiang, George Miles

Cancer Prev Res (Phila)· February 2023

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Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer.
Meenakshi Anurag, Eric J Jaehnig, Karsten Krug, Jonathan T Lei, Erik J Bergstrom, George Miles

Cancer Discov· November 2022

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Esomeprazole enhances the effect of ionizing radiation to improve tumor control.
Kassidy A Hebert, Sergio Jaramillo, Wangjie Yu, Min Wang, Ratna Veeramachaneni, George Miles

Oncotarget· July 2021

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Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma.
Chen Huang, Lijun Chen, Sara R Savage, Rodrigo Vargas Eguez, Yongchao Dou, George Miles

Cancer Cell· March 2021

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Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer.
Elizabeth A Bowling, Jarey H Wang, Fade Gong, William Wu, Nicholas J Neill, George Miles

Cell· January 2021

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Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.
Karsten Krug, Eric J Jaehnig, Shankha Satpathy, Lili Blumenberg, Alla Karpova, George Miles

Cell· November 2020

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Microscaled proteogenomic methods for precision oncology.
Shankha Satpathy, Eric J Jaehnig, Karsten Krug, Beom-Jun Kim, Alexander B Saltzman, George Miles

Nat Commun· January 2020

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Intergenerational effects of CO-induced stream acidification in the Trinidadian guppy ().
Hartley C P H George, George Miles, James Bemrose, Amelia White, Matthew N Bond

Ecol Evol· November 2019

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Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice.
Enrico M Novelli, Lynda Little-Ihrig, Heather E Knupp, Natasha M Rogers, Mingyi Yao, George Miles

Am J Physiol Lung Cell Mol Physiol· June 2019

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Genetic Testing and Tissue Banking for Personalized Oncology: Analytical and Institutional Factors.
George Miles, James Rae, Suresh S Ramalingam, John Pfeifer

Semin Oncol· October 2015

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Hemodynamic predictors of mortality in adults with sickle cell disease.
Alem Mehari, Shoaib Alam, Xin Tian, Michael J Cuttica, Christopher F Barnett, George Miles

Am J Respir Crit Care Med· April 2013

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Concurrent robotic partial adrenalectomy and extra-adrenal pheochromocytoma resection in a pediatric patient with von Hippel-Lindau disease.
Craig G Rogers, Adam M Blatt, George E Miles, W Marston Linehan, Peter A Pinto

J Endourol· July 2008

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Role of the amino latch of staphylococcal alpha-hemolysin in pore formation: a co-operative interaction between the N terminus and position 217.
Lakmal Jayasinghe, George Miles, Hagan Bayley

J Biol Chem· January 2006

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Assembly of the Bi-component leukocidin pore examined by truncation mutagenesis.
George Miles, Lakmal Jayasinghe, Hagan Bayley

J Biol Chem· January 2006

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Properties of Bacillus cereus hemolysin II: a heptameric transmembrane pore.
George Miles, Hagan Bayley, Stephen Cheley

Protein Sci· July 2002

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