Publications by authors named "George P Luke"

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Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors.
Jian Lin, Wei Lu, Justin A Caravella, Ann Marie Campbell, R Bruce Diebold, George P Luke

J Med Chem· July 2019

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Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).
Matthew W Martin, David R Lancia, Hongbin Li, Shawn E R Schiller, Angela V Toms, George P Luke

Bioorg Med Chem Lett· April 2019

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Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains.
David S Millan, Katherine J Kayser-Bricker, Matthew W Martin, Adam C Talbot, Shawn E R Schiller, George P Luke

ACS Med Chem Lett· August 2017

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An efficient preparation of beta-aryl-beta-ketophosphonates by the TFAA/H3PO4-mediated acylation of arenes with phosphonoacetic acids.
George P Luke, Christopher K Seekamp, Zhe-Qing Wang, Bertrand L Chenard

J Org Chem· August 2008

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Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents.
Chi B Vu, George P Luke, Noriyuki Kawahata, William C Shakespeare, Yihan Wang

Bioorg Med Chem Lett· September 2003

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Reaction of Phosgeniminium Salts with Enolates Derived from Lewis Acid Complexes of 2'-Hydroxypropiophenones and Related beta-Diketones.
Joel Morris, George P. Luke, Donn G. Wishka

J Org Chem· May 1996

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