Publications by authors named "George Procopiou"

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Synthesis, SAR, and biophysical mechanism of action of cyclopropabenzindole-pyridinobenzodiazepine (CBI-PDD) guanine-adenine DNA cross-linking agents.
George Procopiou, Paul J M Jackson, Daniella di Mascio, Jennifer L Auer, Paolo Andriollo

Eur J Med Chem· January 2026

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A novel DNA sequence-selective, guanine mono-alkylating ADC payload suitable for solid tumour treatment.
Paolo Andriollo, Daniella di Mascio, Paul J M Jackson, Md Mahbub Hasan, Ilona Pysz-Hosey, George Procopiou

RSC Med Chem· July 2025

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Synthesis of novel pyrrolobenzodiazepine (PBD) C1-substituted monomers and dimers with DNA-binding activity and cytotoxicity.
George Procopiou, Paul J M Jackson, Paolo Andriollo, Md Mahbub Hasan, Nicolas Veillard

Bioorg Med Chem Lett· April 2025

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DNA sequence-selective G-A cross-linking ADC payloads for use in solid tumour therapies.
George Procopiou, Paul J M Jackson, Daniella di Mascio, Jennifer L Auer, Chris Pepper

Commun Biol· July 2022

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Two-directional synthesis and biological evaluation of alkaloid 5-epi-cis-275B'.
George Procopiou, Pooja Aggarwal, Annabella F Newton, David Richards, Ian R Mellor

Chem Commun (Camb)· December 2014

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Cycloaddition of chiral tert-butanesulfinimines with trimethylenemethane.
George Procopiou, William Lewis, Gareth Harbottle, Robert A Stockman

Org Lett· April 2013

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