Publications by authors named "Gerald Appel"

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A meta-analysis of albuminuria as a surrogate endpoint for kidney failure.
Hiddo J L Heerspink, Willem H Collier, Juhi Chaudhari, Shiyuan Miao, Hocine Tighiouart, Gerald B Appel

Nat Med· November 2025

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Author Correction: Exome analysis links kidney malformations to developmental disorders and reveals causal genes.
Hila Milo Rasouly, Sarath Babu Krishna Murthy, Natalie Vena, Gundula Povysil, Andrew Beenken, Gerald B Appel

Nat Commun· October 2025

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Efficacy of Acthar gel and Tacrolimus in DNA-JB9 Positive Fibrillary Glomerulopathy.
James A Tumlin, Amber Podoll, Nelson Kopyt, Brad Rovin, Richard Lafayette, Gerald B Appel

Kidney Int Rep· September 2025

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Exome analysis links kidney malformations to developmental disorders and reveals causal genes.
Hila Milo Rasouly, Sarath Babu Krishna Murthy, Natalie Vena, Gundula Povysil, Andrew Beenken, Gerald B Appel

Nat Commun· August 2025

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Natural History and Clinicopathological Associations of TRPC6-Associated Podocytopathy.
Benjamin Wooden, Andrew Beenken, Elena Martinelli, Ken Saida, Andrea L Knob, Gerald B Appel

J Am Soc Nephrol· February 2025

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Genome-wide studies define new genetic mechanisms of IgA vasculitis.
Lili Liu, Li Zhu, Sara Monteiro-Martins, Aaron Griffin, Lukas J Vlahos, Gerald B Appel

medRxiv· October 2024

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A Randomized Controlled Clinical Trial Testing Effects of Lademirsen on Kidney Function Decline in Adults with Alport Syndrome.
Daniel P Gale, Oliver Gross, Fang Wang, Rafael José Esteban de la Rosa, Matthew Hall, Gerald Appel

Clin J Am Soc Nephrol· August 2024

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C3 Glomerulopathy Recurs Early after Kidney Transplantation in Serial Biopsies Performed within the First 2 Years after Transplantation.
Blanca Tarragón, Yonatan Peleg, Geetha Jagannathan, Miroslav Sekulic, Jae-Hyung Chang, Gerald B Appel

Clin J Am Soc Nephrol· August 2024

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Pathologic-genomic correlation identified a novel variant in FN1 and established the diagnosis of recurrent fibronectin glomerulopathy in the kidney allograft.
Ibrahim Batal, Samih H Nasr, Surendra Dasari, Astrid Weins, Natalie Vena, Gerald B Appel

Am J Transplant· March 2024

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Mayo Clinic consensus report on membranous nephropathy: proposal for a novel classification.
Sanjeev Sethi, Laurence H Beck, Richard J Glassock, Mark Haas, An S De Vriese, Gerald B Appel

Kidney Int· December 2023

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Mayo Clinic Consensus Report on Membranous Nephropathy: Proposal for a Novel Classification.
Sanjeev Sethi, Laurence H Beck, Richard J Glassock, Mark Haas, An S De Vriese, Gerald B Appel

Mayo Clin Proc· November 2023

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Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.
Yask Gupta, David J Friedman, Michelle T McNulty, Atlas Khan, Brandon Lane, Gerald B Appel

Nat Commun· November 2023

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Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy.
Sean J Barbour, Fernando C Fervenza, Dilshani Induruwage, Paul E Brenchley, Brad Rovin, Gerald B Appel

Clin J Am Soc Nephrol· October 2023

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Implementation and Feasibility of Clinical Genome Sequencing Embedded Into the Outpatient Nephrology Care for Patients With Proteinuric Kidney Disease.
Maddalena Marasa, Dina F Ahram, Atteeq U Rehman, Adele Mitrotti, Avinash Abhyankar, Gerald B Appel

Kidney Int Rep· August 2023

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Strong protective effect of the p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.
Yask Gupta, David J Friedman, Michelle McNulty, Atlas Khan, Brandon Lane, Gerald B Appel

medRxiv· August 2023

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A meta-analysis of GFR slope as a surrogate endpoint for kidney failure.
Lesley A Inker, Willem Collier, Tom Greene, Shiyuan Miao, Juhi Chaudhari, Gerald B Appel

Nat Med· July 2023

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Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.
Krzysztof Kiryluk, Elena Sanchez-Rodriguez, Xu-Jie Zhou, Francesca Zanoni, Lili Liu, Gerald B Appel

Nat Genet· July 2023

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Change in Albuminuria and GFR Slope as Joint Surrogate End Points for Kidney Failure: Implications for Phase 2 Clinical Trials in CKD.
Hiddo J L Heerspink, Lesley A Inker, Hocine Tighiouart, Willem H Collier, Benjamin Haaland, Gerald B Appel

J Am Soc Nephrol· June 2023

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Rare Single Nucleotide and Copy Number Variants and the Etiology of Congenital Obstructive Uropathy: Implications for Genetic Diagnosis.
Dina F Ahram, Tze Y Lim, Juntao Ke, Gina Jin, Miguel Verbitsky, Gerald B Appel

J Am Soc Nephrol· June 2023

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Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis.
Laura H Mariani, Sean Eddy, Fadhl M AlAkwaa, Phillip J McCown, Jennifer L Harder, Gerald B Appel

Kidney Int· March 2023

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Glomerular diseases in pregnancy: pragmatic recommendations for clinical management.
Fadi Fakhouri, Nora Schwotzer, Gianfranca Cabiddu, Jonathan Barratt, Hélène Legardeur, Gerald Appel

Kidney Int· February 2023

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Evaluation of Variation in the Performance of GFR Slope as a Surrogate End Point for Kidney Failure in Clinical Trials that Differ by Severity of CKD.
Willem Collier, Lesley A Inker, Benjamin Haaland, Gerald B Appel, Sunil V Badve

Clin J Am Soc Nephrol· February 2023

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Baseline Clinical Characteristics and Complement Biomarkers of Patients with C3 Glomerulopathy Enrolled in Two Phase 2 Studies Investigating the Factor D Inhibitor Danicopan.
Steven D Podos, Howard Trachtman, Gerald B Appel, Andrew S Bomback, Bradley P Dixon

Am J Nephrol· January 2023

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Clinical Outcomes of Patients with C3G or IC-MPGN Treated with the Factor D Inhibitor Danicopan: Final Results from Two Phase 2 Studies.
Carla Nester, Gerald B Appel, Andrew S Bomback, Koenraad Peter Bouman, H Terence Cook

Am J Nephrol· January 2023

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Effects of Bardoxolone Methyl in Alport Syndrome.
Bradley A Warady, Pablo E Pergola, Rajiv Agarwal, Sharon Andreoli, Gerald B Appel

Clin J Am Soc Nephrol· December 2022

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