Publications by authors named "Gerald Linette"

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LOXHD1 is an oncofusion-regulated antigen of ewing sarcoma.
Tatiana Blanchard, Pouya Faridi, Chong Xu, Adham S Bear, Reyaz Ur Rasool, Gerald P Linette

Sci Rep· April 2025

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EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models.
Patrizia Porazzi, Siena Nason, Ziqi Yang, Alberto Carturan, Guido Ghilardi, Gerald P Linette

Cancer Cell· March 2025

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Identification of Core Techniques That Enhance Genome Editing of Human T Cells Expressing Synthetic Antigen Receptors.
Ju-Fang Chang, Nils Wellhausen, Nils W Engel, Jack H Landmann, Caitlin R Hopkins, Gerald P Linette

Cancer Immunol Res· September 2024

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Natural TCRs targeting KRASG12V display fine specificity and sensitivity to human solid tumors.
Adham S Bear, Rebecca B Nadler, Mark H O'Hara, Kelsey L Stanton, Chong Xu, Gerald P Linette

J Clin Invest· September 2024

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CD5 deletion enhances the antitumor activity of adoptive T cell therapies.
Ruchi P Patel, Guido Ghilardi, Yunlin Zhang, Yi-Hao Chiang, Wei Xie, Gerald P Linette

Sci Immunol· July 2024

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Facts and Hopes in Immunotherapy Strategies Targeting Antigens Derived from KRAS Mutations.
Gerald P Linette, Adham S Bear, Beatriz M Carreno

Clin Cancer Res· May 2024

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A genetically encoded protein tag for control and quantitative imaging of CAR T cell therapy.
Iris K Lee, Nitika Sharma, Estela Noguera-Ortega, Maria Liousia, Miren L Baroja, Gerald P Linette

Mol Ther· December 2023

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Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma.
Payal D Shah, Alexander C Huang, Xiaowei Xu, Robert Orlowski, Ravi K Amaravadi, Gerald P Linette

Cancer Res Commun· May 2023

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Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy.
Alfred L Garfall, Adam D Cohen, Sandra P Susanibar-Adaniya, Wei-Ting Hwang, Dan T Vogl, Gerald P Linette

Blood Cancer Discov· March 2023

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Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
Anže Smole, Alexander Benton, Mathilde A Poussin, Monika A Eiva, Claudia Mezzanotte, Gerald P Linette

Cancer Cell· December 2022

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A Phase I Study of Apolizumab, an Anti-HLA-DR ß-chain Monoclonal Antibody, in Patients With Solid Tumor Malignancies.
Paula M Fracasso, Sherry A Goodner, Jonathan D Wildi, Michael J Naughton, Gerald P Linette

Am J Clin Oncol· July 2022

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BAMM (BRAF Autophagy and MEK Inhibition in Melanoma): A Phase I/II Trial of Dabrafenib, Trametinib, and Hydroxychloroquine in Advanced BRAFV600-mutant Melanoma.
Janice M Mehnert, Tara C Mitchell, Alexander C Huang, Tomas S Aleman, Benjamin J Kim, Gerald P Linette

Clin Cancer Res· March 2022

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On the Twentieth Anniversary of Dendritic Cell Vaccines - Riding the Next Wave.
Gerald P Linette, Beatriz M Carreno

Cancer Res· March 2022

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Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments.
Maulasri Bhatta, Gautam N Shenoy, Jenni L Loyall, Brian D Gray, Meghana Bapardekar, Gerald Linette

J Immunother Cancer· October 2021

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Health-related quality of life in patients with malignant melanoma by stage and treatment status.
Abby R Rosenberg, Sara J Weston, Teresa Deshields, Ryan C Fields, Gerald P Linette

J Am Acad Dermatol· August 2021

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Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
Adham S Bear, Tatiana Blanchard, Joseph Cesare, Michael J Ford, Lee P Richman, Gerald P Linette

Nat Commun· July 2021

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Preclinical evaluation of cancer immune therapy using patient-derived tumor antigen-specific T cells in a novel xenograft platform.
Gautam N Shenoy, Christopher J Greene, Maulasri Bhatta, Miren L Baroja, Jenni L Loyall, Gerald P Linette

Clin Transl Immunology· February 2021

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Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial.
Sandra P D'Angelo, Shailender Bhatia, Andrew S Brohl, Omid Hamid, Janice M Mehnert, Gerald P Linette

J Immunother Cancer· May 2020

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Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens.
Gerald P Linette, Michelle Becker-Hapak, Zachary L Skidmore, Miren Lorea Baroja, Chong Xu

Proc Natl Acad Sci U S A· November 2019

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Primary Bone Tumors: Challenges and Opportunities for CAR-T Therapies.
Ian W Folkert, Samir Devalaraja, Gerald P Linette, Kristy Weber, Malay Haldar

J Bone Miner Res· October 2019

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Tumor-Infiltrating Lymphocytes in the Checkpoint Inhibitor Era.
Gerald P Linette, Beatriz M Carreno

Curr Hematol Malig Rep· August 2019

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Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma.
Sandra P D'Angelo, Matthias Hunger, Andrew S Brohl, Paul Nghiem, Shailender Bhatia, Gerald P Linette

Cancer Immunol Immunother· April 2019

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A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma.
Alexander C Huang, Robert J Orlowski, Xiaowei Xu, Rosemarie Mick, Sangeeth M George, Gerald P Linette

Nat Med· March 2019

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RNA-seq for identification of therapeutically targetable determinants of immune activation in human glioblastoma.
Stephen J Bagley, Wei-Ting Hwang, Steven Brem, Gerald P Linette, Donald M O'Rourke

J Neurooncol· January 2019

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Selumetinib in Combination With Dacarbazine in Patients With Metastatic Uveal Melanoma: A Phase III, Multicenter, Randomized Trial (SUMIT).
Richard D Carvajal, Sophie Piperno-Neumann, Ellen Kapiteijn, Paul B Chapman, Stephen Frank, Gerald Linette

J Clin Oncol· April 2018

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