Publications by authors named "Gerard A Pinna"

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Therapeutic Potential of Tricyclic Pyridazinone-Based Molecules: An Overview.
Battistina Asproni, Gérard A Pinna, Paola Corona, Silvia Coinu, Sandra Piras

Int J Mol Sci· April 2025

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Novel Oxadiazole-Quinoxalines as Hybrid Scaffolds with Antitumor Activity.
Paola Corona, Stefania Gessi, Roberta Ibba, Stefania Merighi, Prisco Mirandola, Gérard Aimè Pinna

Int J Mol Sci· February 2025

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RNAseq Analysis of Novel 1,3,4-Oxadiazole Chalcogen Analogues Reveals Anti-Tubulin Properties on Cancer Cell Lines.
Stefano Zoroddu, Luca Sanna, Valentina Bordoni, Weidong Lyu, Gabriele Murineddu, Gerard A Pinna

Int J Mol Sci· July 2023

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Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT receptor interaction.
Battistina Asproni, Marco Catto, Giovanni Loriga, Gabriele Murineddu, Paola Corona, Gérard A Pinna

Bioorg Med Chem· April 2023

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Novel 1,3,4-oxadiazole chalcogen analogues: Synthesis and cytotoxic activity.
Stefano Zoroddu, Paola Corona, Luca Sanna, Federica Borghi, Valentina Bordoni, Gerard A Pinna

Eur J Med Chem· August 2022

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Biological Effects on μ-Receptors Affinity and Selectivity of Arylpropenyl Chain Structural Modification on Diazatricyclodecane Derivatives.
Sandra Piras, Gabriele Murineddu, Giovanni Loriga, Antonio Carta, Enrica Battistello, Gérard Aimè Pinna

Molecules· September 2021

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Target identification of a novel unsymmetrical 1,3,4-oxadiazole derivative with antiproliferative properties.
Lyu Weidong, Luca Sanna, Valentina Bordoni, Zeng Tiansheng, Li Chengxun, Gerard A Pinna

J Cell Physiol· May 2021

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Tricyclic Pyrazole-Based Compounds as Useful Scaffolds for Cannabinoid CB/CB Receptor Interaction.
Battistina Asproni, Gabriele Murineddu, Paola Corona, Gérard A Pinna

Molecules· April 2021

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Synthesis, biological evaluation and docking studies of a novel class of sulfur-bridged diazabicyclo[3.3.1]nonanes.
Gabriele Murineddu, Battistina Asproni, Paola Corona, Stefania Gessi, Stefania Merighi, Gerard A Pinna

Bioorg Chem· September 2020

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Novel N-aryl nicotinamide derivatives: Taking stock on 3,6-diazabicyclo[3.1.1]heptanes as ligands for neuronal acetylcholine receptors.
Gabriele Murineddu, Cecilia Gotti, Battistina Asproni, Paola Corona, Katiuscia Martinello, Gerard A Pinna

Eur J Med Chem· October 2019

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A diethylpyrocarbonate-based derivatization method for the LC-MS/MS measurement of plasma arginine and its chemically related metabolites and analogs.
Salvatore Sotgia, Angelo Zinellu, Panagiotis Paliogiannis, Gerard A Pinna, Arduino A Mangoni

Clin Chim Acta· May 2019

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Development of Oxygen-Bridged Pyrazole-Based Structures as Cannabinoid Receptor 1 Ligands.
Gabriele Murineddu, Battistina Asproni, Paola Corona, Sandra Piras, Paolo Lazzari, Gérard A Pinna

Molecules· April 2019

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Development of an LC⁻Tandem Mass Spectrometry Method for the Quantitative Analysis of Hercynine in Human Whole Blood.
Salvatore Sotgia, Rhys B Murphy, Angelo Zinellu, David Elliot, Panagiotis Paliogiannis, Gerard Aimè Pinna

Molecules· December 2018

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Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Type 2 Ligands.
Giulio Ragusa, Serena Bencivenni, Paula Morales, Tyra Callaway, Dow P Hurst, Gerard A Pinna

ChemMedChem· June 2018

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Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for αβ nACh receptors.
Francesco Deligia, Gabriele Murineddu, Cecilia Gotti, Giulio Ragusa, Francesca Fasoli, Gerard A Pinna

Eur J Med Chem· May 2018

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Novel pyrrolocycloalkylpyrazole analogues as CB ligands.
Battistina Asproni, Ilaria Manca, Giansalvo Pinna, Elena Cichero, Paola Fossa, Gérard A Pinna

Chem Biol Drug Des· January 2018

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Novel sulfenamides and sulfonamides based on pyridazinone and pyridazine scaffolds as CB receptor ligand antagonists.
Gabriele Murineddu, Francesco Deligia, Giulio Ragusa, Laura García-Toscano, María Gómez-Cañas, Gerard A Pinna

Bioorg Med Chem· January 2018

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New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking.
Giulio Ragusa, María Gómez-Cañas, Paula Morales, Carmen Rodríguez-Cueto, María R Pazos, Gerard A Pinna

Eur J Med Chem· February 2017

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Correction to Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles.
Valentina Nieddu, Giansalvo Pinna, Irene Marchesi, Luca Sanna, Battistina Asproni, Gerard A Pinna

J Med Chem· February 2017

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Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles.
Valentina Nieddu, Giansalvo Pinna, Irene Marchesi, Luca Sanna, Battistina Asproni, Gerard A Pinna

J Med Chem· December 2016

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Synthesis, molecular modeling and SAR study of novel pyrazolo[5,1-f][1,6]naphthyridines as CB receptor antagonists/inverse agonists.
Antonio Dore, Battistina Asproni, Alessia Scampuddu, Stefania Gessi, Gabriele Murineddu, Gérard A Pinna

Bioorg Med Chem· November 2016

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A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives.
Paolo Lazzari, Rita Distinto, Ilaria Manca, Gemma Baillie, Gabriele Murineddu, Gérard Aimè Pinna

Eur J Med Chem· October 2016

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Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties.
Valeria Deiana, María Gómez-Cañas, M Ruth Pazos, Javier Fernández-Ruiz, Battistina Asproni, Gerard A Pinna

Eur J Med Chem· April 2016

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Design of novel 3,6-diazabicyclo[3.1.1]heptane derivatives with potent and selective affinities for α4β2 neuronal nicotinic acetylcholine receptors.
Francesco Deligia, Valeria Deiana, Cecilia Gotti, Paolo Lazzari, Mirko E H Bottazzi, Gerard A Pinna

Eur J Med Chem· October 2015

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Novel diazabicycloalkane delta opioid agonists.
Giovanni Loriga, Paolo Lazzari, Ilaria Manca, Stefania Ruiu, Matteo Falzoi, Giovanni Pinna, Gérard Aimè Pinna

Bioorg Med Chem· September 2015

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