Publications by authors named "Gerard D Wright"

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Sterol-C4-methyl-oxidase Erg251 governs Candida albicans hypoxic growth, commensalism and virulence.
Zhongle Liu, Bonnie Yiu, Pauline Basso, Xuefei Chen, Disha Patel, Gerard D Wright

Nat Commun· December 2025

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The Histidine Kinase VraS Interacts with Vancomycin and Penicillins Through its Membrane-Anchored N-terminal Domain.
Melisa B Antinori, Melani D Peralta, Irina P Suárez, David Sychantha, Kalinka Koteva, Gerard D Wright

Angew Chem Int Ed Engl· November 2025

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Fragment-based drug design of a bacterial kinase inhibitor capable of increasing the antibiotic sensitivity of clinical isolates.
Julien Kowalewski, Robin Deutscher, Marion Richardoz, Mathilde Tomaszczyk, Muriel Gelin, Gerard D Wright

Commun Chem· November 2025

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Author Correction: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome.
Manoj Jangra, Dmitrii Y Travin, Elena V Aleksandrova, Manpreet Kaur, Lena Darwish, Gerard D Wright

Nature· September 2025

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Coniontins, lipopetaibiotics active against Candida auris identified from a microbial natural product fractionation library.
Xuefei Chen, Kalinka Koteva, Sommer Chou, Allison Guitor, Daniel Pallant, Gerard D Wright

Nat Commun· August 2025

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Butyrolactol A potentiates caspofungin efficacy against resistant fungi via phospholipid flippase inhibition.
Xuefei Chen, H Diessel Duan, Michael J Hoy, Kalinka Koteva, Michaela Spitzer, Gerard D Wright

bioRxiv· July 2025

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A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome.
Manoj Jangra, Dmitrii Y Travin, Elena V Aleksandrova, Manpreet Kaur, Lena Darwish, Gerard D Wright

Nature· April 2025

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CARPDM: cost-effective antibiotic resistome profiling of metagenomic samples using targeted enrichment.
Dirk Hackenberger, Hamna Imtiaz, Amogelang R Raphenya, Brian P Alcock, Hendrik N Poinar, Gerard D Wright

Appl Environ Microbiol· March 2025

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Revisiting the potential of natural products in antimycobacterial therapy: advances in drug discovery and semisynthetic solutions.
Maya George, Gerard D Wright

Curr Opin Microbiol· February 2025

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Fungal impacts on Earth's ecosystems.
Nicola T Case, Sarah J Gurr, Matthew C Fisher, David S Blehert, Charles Boone, Gerard D Wright

Nature· February 2025

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The Janus Effect: The Biochemical Logic of Antibiotic Resistance.
Gerard D Wright

Biochemistry· January 2025

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Identification and characterization of the siderochelin biosynthetic gene cluster coculture.
Adam J Schaenzer, Wenliang Wang, Dirk Hackenberger, Gerard D Wright

mBio· October 2024

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Diversity, functional classification and genotyping of SHV β-lactamases in .
Kara K Tsang, Margaret M C Lam, Ryan R Wick, Kelly L Wyres, Michael Bachman, Gerard D Wright

Microb Genom· October 2024

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Efficacy of aspergillomarasmine A/meropenem combinations with and without avibactam against bacterial strains producing multiple β-lactamases.
Caitlyn M Rotondo, Gerard D Wright

Antimicrob Agents Chemother· September 2024

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Minimal Impact on the Resistome of Children in Botswana After Azithromycin Treatment for Acute Severe Diarrheal Disease.
Allison K Guitor, Anna Katyukhina, Margaret Mokomane, Kwana Lechiile, David M Goldfarb, Gerard D Wright

J Infect Dis· July 2024

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Antibiotic resistance: A key microbial survival mechanism that threatens public health.
Amna Abbas, Alexandra Barkhouse, Dirk Hackenberger, Gerard D Wright

Cell Host Microbe· June 2024

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Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes.
David Sychantha, Xuefei Chen, Kalinka Koteva, Gerd Prehna, Gerard D Wright

Nat Commun· May 2024

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Seeing the whole elephant: designing 'one health' governance to fight antimicrobial resistance.
Ian Brunskill, Deborah S Somanader, Maureen Perrin, Herman W Barkema, Sean Hillier, Gerard D Wright

Clin Microbiol Infect· April 2024

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Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity.
Emily Puumala, David Sychantha, Elizabeth Lach, Shawn Reeves, Sunna Nabeela, Gerard D Wright

Cell Chem Biol· April 2024

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Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance.
Emily Bordeleau, Peter J Stogios, Elena Evdokimova, Kalinka Koteva, Alexei Savchenko, Gerard D Wright

Nat Chem Biol· February 2024

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Angucyclinones rescue PhLOPS antibiotic activity by inhibiting Cfr-dependent antibiotic resistance.
Adam J Schaenzer, Annia Rodriguez Hernandez, Kaitlyn Tsai, Christian Hobson, Danica Galonić Fujimori, Gerard D Wright

mBio· December 2023

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susceptibility to complestatin and corbomycin depends on the VraSR two-component system.
Carmen Gómez-Arrebola, Sara B Hernandez, Elizabeth J Culp, Gerard D Wright, Cristina Solano

Microbiol Spectr· August 2023

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Toward a Universal Unit for Quantification of Antibiotic Resistance Genes in Environmental Samples.
Xiaole Yin, Xi Chen, Xiao-Tao Jiang, Ying Yang, Bing Li, Gerard D Wright

Environ Sci Technol· July 2023

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Synthetic Biology Facilitates Semisynthetic Development of Type V Glycopeptide Antibiotics Targeting Vancomycin-Resistant .
Kalinka Koteva, Min Xu, Wenliang Wang, Aline A Fiebig-Comyn, Michael A Cook, Gerard D Wright

J Med Chem· July 2023

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Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory.
Michael A Cook, Daniel Pallant, Linda Ejim, Arlene D Sutherland, Xiaodong Wang, Gerard D Wright

J Ind Microbiol Biotechnol· February 2023

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