Publications by authors named "Gerhard Meissner"

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Structural and functional interactions between the EF hand domain and S2-S3 loop in the type-1 ryanodine receptor ion channel.
Venkat R Chirasani, Millar Elferdink, MacKenzie Kral, Jordan S Carter, Savannah Heitmann, Gerhard Meissner

J Biol Chem· February 2024

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Mapping co-regulatory interactions among ligand-binding sites in ryanodine receptor 1.
Venkat R Chirasani, Konstantin I Popov, Gerhard Meissner, Nikolay V Dokholyan

Proteins· February 2022

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Structural and functional interactions between the Ca-, ATP-, and caffeine-binding sites of skeletal muscle ryanodine receptor (RyR1).
Venkat R Chirasani, Daniel A Pasek, Gerhard Meissner

J Biol Chem· September 2021

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Single-channel properties of skeletal muscle ryanodine receptor pore ΔFF in two brothers with a lethal form of fetal akinesia.
Le Xu, Frederike L Harms, Venkat R Chirasani, Daniel A Pasek, Fanny Kortüm, Gerhard Meissner

Cell Calcium· May 2020

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A central core disease mutation in the Ca-binding site of skeletal muscle ryanodine receptor impairs single-channel regulation.
Venkat R Chirasani, Le Xu, Hannah G Addis, Daniel A Pasek, Nikolay V Dokholyan, Gerhard Meissner

Am J Physiol Cell Physiol· August 2019

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Ca-mediated activation of the skeletal-muscle ryanodine receptor ion channel.
Le Xu, Venkat R Chirasani, Jordan S Carter, Daniel A Pasek, Nikolay V Dokholyan, Gerhard Meissner

J Biol Chem· December 2018

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G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to cytosolic and luminal Ca.
Le Xu, David D Mowrey, Venkat R Chirasani, Ying Wang, Daniel A Pasek, Gerhard Meissner

J Biol Chem· February 2018

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The structural basis of ryanodine receptor ion channel function.
Gerhard Meissner

J Gen Physiol· December 2017

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Two EF-hand motifs in ryanodine receptor calcium release channels contribute to isoform-specific regulation by calmodulin.
Le Xu, Angela C Gomez, Daniel A Pasek, Gerhard Meissner, Naohiro Yamaguchi

Cell Calcium· September 2017

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Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor.
David D Mowrey, Le Xu, Yingwu Mei, Daniel A Pasek, Gerhard Meissner

J Biol Chem· August 2017

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IL-6/STAT3 signaling in mice with dysfunctional type-2 ryanodine receptor.
Tai-Qin Huang, Monte S Willis, Gerhard Meissner

JAKSTAT· May 2016

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Inhibition of CaMKII does not attenuate cardiac hypertrophy in mice with dysfunctional ryanodine receptor.
Asima Chakraborty, Daniel A Pasek, Tai-Qin Huang, Angela C Gomez, Naohiro Yamaguchi, Gerhard Meissner

PLoS One· November 2015

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Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor.
Yingwu Mei, Le Xu, David D Mowrey, Raul Mendez Giraldez, Ying Wang, Gerhard Meissner

J Biol Chem· July 2015

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PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.
Liang Xie, Xinchun Pi, W H Davin Townley-Tilson, Na Li, Xander H T Wehrens, Gerhard Meissner

J Clin Invest· July 2015

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Dyad content is reduced in cardiac myocytes of mice with impaired calmodulin regulation of RyR2.
Manuela Lavorato, Tai-Qin Huang, Venkat Ramesh Iyer, Stefano Perni, Gerhard Meissner

J Muscle Res Cell Motil· April 2015

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mTOR signaling in mice with dysfunctional cardiac ryanodine receptor ion channel.
Tai-Qin Huang, Min-Xu Zou, Daniel A Pasek, Gerhard Meissner

J Receptor Ligand Channel Res· January 2015

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Selecting ions by size in a calcium channel: the ryanodine receptor case study.
Dirk Gillespie, Le Xu, Gerhard Meissner

Biophys J· November 2014

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Pore dynamics and conductance of RyR1 transmembrane domain.
David Shirvanyants, Srinivas Ramachandran, Yingwu Mei, Le Xu, Gerhard Meissner

Biophys J· June 2014

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Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure.
Yi Yang, Tao Guo, Tetsuro Oda, Asima Chakraborty, Le Chen, Gerhard Meissner

Circ Res· January 2014

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Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia.
Carlo Manno, Lourdes Figueroa, Leandro Royer, Sandrine Pouvreau, Chang Seok Lee, Gerhard Meissner

J Physiol· September 2013

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Cardiac calcium signalling pathologies associated with defective calmodulin regulation of type 2 ryanodine receptor.
Juan José Arnáiz-Cot, Brooke James Damon, Xiao-Hua Zhang, Lars Cleemann, Naohiro Yamaguchi, Gerhard Meissner

J Physiol· September 2013

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Stabilization of the skeletal muscle ryanodine receptor ion channel-FKBP12 complex by the 1,4-benzothiazepine derivative S107.
Yingwu Mei, Le Xu, Henning F Kramer, Ginger H Tomberlin, Claire Townsend, Gerhard Meissner

PLoS One· July 2013

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Cardiac hypertrophy associated with impaired regulation of cardiac ryanodine receptor by calmodulin and S100A1.
Naohiro Yamaguchi, Asima Chakraborty, Tai-Qin Huang, Le Xu, Angela C Gomez, Gerhard Meissner

Am J Physiol Heart Circ Physiol· July 2013

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Structural determinants of skeletal muscle ryanodine receptor gating.
Srinivas Ramachandran, Asima Chakraborty, Le Xu, Yingwu Mei, Montserrat Samsó, Gerhard Meissner

J Biol Chem· March 2013

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Detection of calcium release via ryanodine receptors.
Jerry P Eu, Gerhard Meissner

Methods Mol Biol· April 2012

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