Publications by authors named "Gerrit Wilms"

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Dyr726, a brain-penetrant inhibitor of PI3Kα, Type III receptor tyrosine kinases, and WNT signaling.
Vasudha Tandon, Alessandra Fistrovich, Joaquina Nogales, Febe Ferro, Samantha N Rokey, Gerrit Wilms

bioRxiv· March 2025

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Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B.
Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw

J Med Chem· October 2024

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Differential regulation of expression of the protein kinases DYRK1A and DYRK1B in cancer cells.
Vincent Andreas Vorwerk, Gerrit Wilms, Aaron Babendreyer, Walter Becker

Sci Rep· October 2024

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Elevated expression levels of the protein kinase DYRK1B induce mesenchymal features in A549 lung cancer cells.
Soraya Sester, Gerrit Wilms, Joana Ahlburg, Aaron Babendreyer, Walter Becker

BMC Cancer· October 2024

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Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B.
Marco Papenfuss, Svenja Lützow, Gerrit Wilms, Aaron Babendreyer, Maren Flaßhoff

Sci Rep· February 2022

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Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects.
Yasmeen T AlNajjar, Moustafa Gabr, Ahmed K ElHady, Mohamed Salah, Gerrit Wilms

Eur J Med Chem· January 2022

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Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases.
Youssef Aboushady, Moustafa Gabr, Ahmed K ElHady, Mohamed Salah, Ashraf H Abadi, Gerrit Wilms

ACS Chem Neurosci· November 2021

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A New Species-Specific Typing Method for Salivarius Group Streptococci Based on the Dephospho-Coenzyme A Kinase () Gene Sequencing.
Mohamed M H Abdelbary, Gerrit Wilms, Georg Conrads

Front Cell Infect Microbiol· August 2021

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