Publications by authors named "Gerwald Jogl"

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Rapid DNA cleavage by the LINE-1 endonuclease proximal to DNA ends and at mismatches.
Bryant D Miller, Benedict A Smail, Trevor Van Eeuwen, Hanna Kodama, Kazuma Kondo, Gerwald Jogl

J Biol Chem· November 2025

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Structural and dynamic impacts of single-atom disruptions to guide RNA interactions within the recognition lobe of Cas9.
Helen B Belato, Alexa L Knight, Alexandra M D'Ordine, Chinmai Pindi, Zhiqiang Fan, Gerwald Jogl

Elife· May 2025

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Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Cas9.
Helen B Belato, Alexa L Knight, Alexandra M D'Ordine, Chinmai Pindi, Zhiqiang Fan, Gerwald Jogl

bioRxiv· March 2025

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Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease.
Alexandra M D'Ordine, Gerwald Jogl, John M Sedivy

Nat Commun· May 2024

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High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9.
Erin Skeens, Souvik Sinha, Mohd Ahsan, Alexandra M D'Ordine, Gerwald Jogl

Sci Adv· March 2024

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Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain.
Nathaniel E Clark, Adam Katolik, Pascal Gallant, Anastasia Welch, Eileen Murphy, Gerwald Jogl

J Biol Chem· September 2023

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High-Fidelity, Hyper-Accurate, and Evolved Mutants Rewire Atomic Level Communication in CRISPR-Cas9.
Erin Skeens, Souvik Sinha, Mohd Ahsan, Alexandra M D'Ordine, Gerwald Jogl

bioRxiv· August 2023

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Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage.
Helen B Belato, Carmelissa Norbrun, Jinping Luo, Chinmai Pindi, Souvik Sinha, Gerwald Jogl

J Chem Phys· December 2022

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Structural and dynamic insights into the HNH nuclease of divergent Cas9 species.
Helen B Belato, Alexandra M D'Ordine, Lukasz Nierzwicki, Pablo R Arantes, Gerwald Jogl

J Struct Biol· March 2022

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A Survey of Spontaneous Antibiotic-Resistant Mutants of the Halophilic, Thermophilic Bacterium .
Sophia Silvia, Samantha A Donahue, Erin E Killeavy, Gerwald Jogl, Steven T Gregory

Antibiotics (Basel)· November 2021

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Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain.
Jocelyn C Newton, Mandar T Naik, Grace Y Li, Eileen L Murphy, Nicolas L Fawzi, Gerwald Jogl

Biophys J· June 2021

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Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Eileen L Murphy, Kavindra V Singh, Bryant Avila, Torsten Kleffmann, Steven T Gregory, Gerwald Jogl

Sci Rep· October 2020

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Tiamulin-Resistant Mutants of the Thermophilic Bacterium .
Erin E Killeavy, Gerwald Jogl, Steven T Gregory

Antibiotics (Basel)· June 2020

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Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics.
Kyle W East, Jocelyn C Newton, Uriel N Morzan, Yogesh B Narkhede, Atanu Acharya, Gerwald Jogl

J Am Chem Soc· January 2020

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The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism.
Lian Duan, Gerwald Jogl, David E Cane

J Am Chem Soc· September 2016

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Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation.
Guray Kuzu, Emily G Kaye, Jessica Chery, Trevor Siggers, Lin Yang, Gerwald Jogl

PLoS Genet· July 2016

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Phenotypic Suppression of Streptomycin Resistance by Mutations in Multiple Components of the Translation Apparatus.
Jennifer F Carr, Hannah J Lee, Joshua B Jaspers, Albert E Dahlberg, Gerwald Jogl

J Bacteriol· September 2015

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Phenotypic interactions among mutations in a Thermus thermophilus 16S rRNA gene detected with genetic selections and experimental evolution.
Steven T Gregory, Jacqueline L Connetti, Jennifer F Carr, Gerwald Jogl, Albert E Dahlberg

J Bacteriol· November 2014

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Structural analysis of base substitutions in Thermus thermophilus 16S rRNA conferring streptomycin resistance.
Hasan Demirci, Frank V Murphy, Eileen L Murphy, Jacqueline L Connetti, Albert E Dahlberg, Gerwald Jogl

Antimicrob Agents Chemother· August 2014

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The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Hasan Demirci, Leyi Wang, Frank V Murphy, Eileen L Murphy, Jennifer F Carr, Gerwald Jogl

RNA· December 2013

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Serial femtosecond X-ray diffraction of 30S ribosomal subunit microcrystals in liquid suspension at ambient temperature using an X-ray free-electron laser.
Hasan Demirci, Raymond G Sierra, Hartawan Laksmono, Robert L Shoeman, Sabine Botha, Gerwald Jogl

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2013

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A structural basis for streptomycin-induced misreading of the genetic code.
Hasan Demirci, Frank Murphy, Eileen Murphy, Steven T Gregory, Albert E Dahlberg, Gerwald Jogl

Nat Commun· June 2013

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Crystal structure of decaprenylphosphoryl-β- D-ribose 2'-epimerase from Mycobacterium smegmatis.
Hua Li, Gerwald Jogl

Proteins· March 2013

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Identification and characterization of the Thermus thermophilus 5-methylcytidine (m5C) methyltransferase modifying 23 S ribosomal RNA (rRNA) base C1942.
Line H G Larsen, Anette Rasmussen, Anders M B Giessing, Gerwald Jogl, Finn Kirpekar

J Biol Chem· August 2012

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High-resolution neutron crystallographic studies of the hydration of the coenzyme cob(II)alamin.
Gerwald Jogl, Xiaoping Wang, Sax A Mason, Andrey Kovalevsky, Marat Mustyakimov

Acta Crystallogr D Biol Crystallogr· June 2011

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