Publications by authors named "Ghazl Al Hamwi"

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Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in human mast cells and disease models.
Ghazl Al Hamwi, Mohamad Wessam Alnouri, Sven Verdonck, Piotr Leonczak, Shaswati Chaki

Signal Transduct Target Ther· April 2025

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Design, Synthesis, and Unprecedented Interactions of Covalent Dipeptide-Based Inhibitors of SARS-CoV-2 Main Protease and Its Variants Displaying Potent Antiviral Activity.
Philipp Flury, Nadine Krüger, Katharina Sylvester, Julian Breidenbach, Ghazl Al Hamwi

J Med Chem· February 2025

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Nonpeptidic Irreversible Inhibitors of SARS-CoV-2 Main Protease with Potent Antiviral Activity.
Angelo Oneto, Ghazl Al Hamwi, Laura Schäkel, Nadine Krüger, Katharina Sylvester

J Med Chem· September 2024

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Proinflammatory chemokine CXCL14 activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2.
Ghazl Al Hamwi, Vigneshwaran Namasivayam, Beatriz Büschbell, Robin Gedschold, Stefan Golz

Commun Biol· January 2024

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Discovery of Potent Agonists for the Predominant Variant of the Orphan MAS-Related G Protein-Coupled Receptor X4 (MRGPRX4).
Daniel Marx, Mohamed Wessam Alnouri, Sophie Clemens, Robin Gedschold, Yvonne Riedel, Ghazl Al Hamwi

J Med Chem· December 2023

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MAS-related G protein-coupled receptors X (MRGPRX): Orphan GPCRs with potential as targets for future drugs.
Ghazl Al Hamwi, Yvonne K Riedel, Sophie Clemens, Vigneshwaran Namasivayam, Dominik Thimm

Pharmacol Ther· October 2022

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Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors.
Julian Breidenbach, Carina Lemke, Thanigaimalai Pillaiyar, Laura Schäkel, Ghazl Al Hamwi

Angew Chem Int Ed Engl· April 2021

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