Publications by authors named "Gilbert Fruhwirth"

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Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential.
Ana-Rita Pedrosa, Alejandro Castillo-Kauil, Yuliia Kravchuk, Louise Reynolds, Bruce Williams, Gilbert O Fruhwirth

J Pathol· August 2025

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Stromal lipid species dictate melanoma metastasis and tropism.
Shilpa Gurung, Timothy Budden, Karthik Mallela, Benjamin Jenkins, Alex von Kriegsheim, Gilbert Fruhwirth

Cancer Cell· June 2025

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Meeting Report: The Sixth International Sam Strober Workshop on Clinical Immune Tolerance.
Helen Stark, Quan Yao Ho, Amy Cross, Alessandro Alessandrini, Alice Bertaina, Gilbert Fruhwirth

Transplantation· April 2025

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Gene editing enables non-invasive PET imaging of human induced pluripotent stem cell-derived liver bud organoids.
Candice Ashmore-Harris, Hiroaki Ayabe, Emi Yoshizawa, Tetsu Arisawa, Yuuki Takada, Gilbert O Fruhwirth

Mol Ther Methods Clin Dev· March 2025

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An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities.
Lais C G F Palhares, Melanie Grandits, Katie Stoker, Jitesh Chauhan, Heng Sheng Sow, Gilbert O Fruhwirth

J Exp Clin Cancer Res· February 2025

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Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis.
Oscar Maiques, Marta C Sallan, Roman Laddach, Pahini Pandya, Adrian Varela, Gilbert O Fruhwirth

Nat Commun· February 2025

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In Vitro and Preclinical Systematic Dose-Effect Studies of Auger Electron- and β Particle-Emitting Radionuclides and External Beam Radiation for Cancer Treatment.
Ines M Costa, George Firth, Jana Kim, Arshiya Banu, Truc T Pham, Gilbert O Fruhwirth

Int J Radiat Oncol Biol Phys· November 2024

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Validation of the plasmid study to relate DNA damaging effects of radionuclides to those from external beam radiotherapy.
Elise Verger, Jordan Cheng, Vittorio de Santis, Madeleine Iafrate, Jessica A Jackson, Gilbert O Fruhwirth

Nucl Med Biol· July 2024

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Combined Vorinostat and Chloroquine Inhibit Sodium-Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo.
Martin L Read, Katie Brookes, Ling Zha, Selvambigai Manivannan, Jana Kim, Gilbert O Fruhwirth

Clin Cancer Res· April 2024

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Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter system.
Piotr Dzien, Ximena Raffo Iraolagoitia, Stephanie May, David Stevenson, Lynn McGarry, Gilbert Fruhwirth

Res Sq· April 2024

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Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers.
R Sumanth Iyer, Sarah R Needham, Ioannis Galdadas, Benjamin M Davis, Selene K Roberts, Gilbert O Fruhwirth

Nat Commun· March 2024

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Co-delivery of PD-L1- and EGFR-targeting siRNAs by synthetic PEG-KL4 peptide to the lungs as potential strategy against non-small cell lung cancer.
Rico C H Man, Yingshan Qiu, Susan W S Leung, Gilbert O Fruhwirth, Jenny K W Lam

Eur J Pharm Biopharm· February 2024

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The Basics of Visualizing, Analyzing, and Reporting Preclinical PET/CT Imaging Data.
Christopher J Cawthorne, Alessia Volpe, Gilbert O Fruhwirth

Methods Mol Biol· November 2023

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Genetic Engineering of Therapeutic Cells with the Sodium Iodide Symporter (NIS) to Enable Noninvasive In Vivo Therapy Tracking.
Ben Grimsdell, Adeel Saleem, Alessia Volpe, Gilbert O Fruhwirth

Methods Mol Biol· November 2023

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Spatiotemporal quantitative microRNA-155 imaging reports immune-mediated changes in a triple-negative breast cancer model.
Elena Skourti, Alessia Volpe, Cameron Lang, Preeth Johnson, Fani Panagaki, Gilbert O Fruhwirth

Front Immunol· June 2023

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Radiolabelling of Polyclonally Expanded Human Regulatory T Cells (Treg) with Zr-oxine for Medium-Term Cell Tracking.
Jacinta Jacob, Alessia Volpe, Qi Peng, Robert I Lechler, Lesley A Smyth, Gilbert O Fruhwirth

Molecules· February 2023

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Radiolabelling Pt-based quadruplex DNA binders via click chemistry.
Rainbow Lo, Aatikah Majid, Gilbert O Fruhwirth, Ramon Vilar

Bioorg Med Chem· December 2022

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Generation of In Vivo Traceable Hepatocyte-Like Cells from Human iPSCs.
Candice Ashmore-Harris, Gilbert O Fruhwirth

Methods Mol Biol· September 2022

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Editorial to the Special Issue Entitled "Imaging in Immunooncology".
Gilbert O Fruhwirth, Bettina Weigelin, Heike E Daldrup-Link, Vladimir Ponomarev

Mol Imaging Biol· April 2022

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PET Imaging of Small Extracellular Vesicles [Zr]Zr(oxinate) Direct Radiolabeling.
Azalea A Khan, Francis Man, Farid N Faruqu, Jana Kim, Fahad Al-Salemee, Gilbert O Fruhwirth

Bioconjug Chem· March 2022

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Relationship of In Vitro Toxicity of Technetium-99m to Subcellular Localisation and Absorbed Dose.
Ines M Costa, Noor Siksek, Alessia Volpe, Francis Man, Katarzyna M Osytek, Gilbert O Fruhwirth

Int J Mol Sci· December 2021

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Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive.
Yasmin R Mohseni, Adeel Saleem, Sim L Tung, Caroline Dudreuilh, Cameron Lang, Gilbert O Fruhwirth

Eur J Immunol· October 2021

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Options for imaging cellular therapeutics in vivo: a multi-stakeholder perspective.
Brooke M Helfer, Vladimir Ponomarev, P Stephen Patrick, Philip J Blower, Alexandra Feitel, Gilbert O Fruhwirth

Cytotherapy· September 2021

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F-FDG PET/CT use in functional assessment of the testes: A systematic review.
Antoni Bochiński, Arunan Sujenthiran, Mohamed Al-Hussini, Gilbert O Fruhwirth, Majed Shabbir

Andrology· September 2021

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A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma.
Oscar Maiques, Bruce Fanshawe, Eva Crosas-Molist, Irene Rodriguez-Hernandez, Alessia Volpe, Gilbert O Fruhwirth

Br J Cancer· August 2021

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